CAS: 2055-97-2; 4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodobenzoic Acid
该化合物是有机化合物,其复杂结构特征为多种碘替代物和苯球氢氧基组,该化合物属于碘化苯酸类,因其在药用化学中的潜在用途和成像技术中的对比剂而闻名;碘原子的存在增强了其放射性,使其在各种诊断程序中有用;氢氧基化合物有助于其溶解性和再活性,允许生物系统中的潜在互动;此外,该化合物的结构特征可能会影响其生物活动,包括抗微生物或抗癌特性;其合成通常涉及多步反应,包括卤化和化过程;与许多碘化化合物一样,必须注意其环境影响和生物影响,特别是碘在甲状腺功能中的作用;
- 英文名称4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodobenzoic Acid
- 中文名称左旋甲状腺素EP杂质H
- IUPAC名称4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzoic acid
- 其它别名3,3',5,5'-Tetraiodo Thyroformic Acid, >90Per Cent; 3,3',5,5'-Tetraiodothyroformic Acid; Levothyroxine Sodium Impurity H [ep Impurity]; Hkjuompympxlfs-Uhfffaoysa-N; Levothyroxine T4 Benzoic Acid; 3,3',5,5'-Tetraiodothyroformic Acid; A
- CAS编号2055-97-2
- MFCD编号:MFCD00016514
- FDA UNII编号:069P3V0KG2
- 分子式:C13H6I4O4分子量:733.8
- 产品CID: 1042300
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
物理性质
合成工艺路线路线简述
海关参考信息
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专利信息
专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.
专利号:CN-112094324-B
优先权日:2020-09-21
标 题 :Synthesis method of carbetocin
