CAS: 205319-10-4; Dichloro[9,9-Dimethyl-4,5-Bis(Diphenylphosphino)Xanthene]Palladium(Ii)

4,5-双二苯基膦-9,9-二甲基氧杂蒽,Palladium Dichloride 以 二氯甲烷,乙腈 用作溶剂,化学反应生成二氯[9,9-二甲基-4,5-二(二苯基膦基)氧杂蒽]钯
参考文献:P,P和p,S型双齿配体的钯配合物:对suzuki-Miyaura交叉偶联反应的影响
标题:P,P和p,S型双齿配体的钯配合物:对suzuki-Miyaura交叉偶联反应的影响
摘要:类型[的pdcl的新钯络合物2(η 2-(p∩p)]图1A,1B)和[的pdcl 2(η 2-P∩s)](1C,1D)已经通过的pdcl反应合成2具有1:1摩尔比的p,P和p,S型双齿配体,其中p∩p= 9,9-二甲基-4,5-双(二苯基膦基)氧杂蒽{xantphos}(a)或bis(2-二苯基膦基苯基)醚{dpephos}(b); P∩s= 9,9-二甲基-4,5-双(二苯基-膦基)氧杂蒽硫醚{xantphos(S)} (c)或双(2-二苯基膦基苯基)醚单硫化物(dpephos(S)}(d).配合物的特征在于元素分析,质谱,1 H,13 C和31 P NMR光谱以及1A和1D的单晶x射线结构测定.所有配合物中的钯原子占据由p原子,P / S原子和两个cl原子形成的略微扭曲的方形平面环境的中心.在室温下,Suzuki-Miyaura交叉偶联反应研究的1A-1D的催化活性比pdcl
Doi:10.1016/j.Jorganchem.2011.10.001

专利信息

专利号:WO-2025104624-A1
优先权日:2023-11-14
标题 :Synthesis of 1,5-anhydro-3-({5-chloro-4-[4-fluoro-2-(2-hydroxypropan-2-yl)-1-(propan-2-yl)-1h-benzimidazol-6-yl]pyrimidin-2-yl}amino)-2,3-dideoxy-d-threo-pentitol
发明人：ALEXANDER KATY LOUISE; ANSARI ZARRIN FAZAL KHADIJA; DANIELS DAVID SYDNEY BERNARD; HASSEL LUKE HARRY; KEEN STEPHEN PHILIP; SCOTT JEREMY PETER; SCOTT REUBEN JOHN; SIMMONS JOHATHAN ANDREW; STOLL EMMA LOUISE; TRINDADE ALEXANDRE FONSECA; VICINI ANNA CHIARA
权利人:PFIZER
摘要:This disclosure relates novel methods to prepare 1,5-anhydro-3-({5-chloro-4-[4- fluoro-2-(2-hydroxypropan-2-yl)-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2- yl}amino)-2,3-dideoxy-D-threo-pentitol, and hydrates and stereoisomers thereof, as well as intermediates, including solid forms of the intermediates, useful for the preparation of such compounds and the synthesis of said intermediates.

专利号:US-11767302-B2
优先权日:2020-10-01
标题 :Reagents and methods for tetrazine synthesis
发明人：FOX JOSEPH M; LAMBERT WILLIAM; FANG YINZHI; AM ENDE CHRISTOPHER WILLIAM; MAHAPATRA SUBHAM; XIE YIXIN; WANG CHUANQI
权利人:UNIV DELAWARE
摘要:Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine.

专利号:CN-117897379-A
优先权日:2021-08-30
标 题:Process for the synthesis of naphthyridine derivatives and intermediates thereof