CAS: 123639-56-5; L-N-Benzylserine Methyl Ester

相似化合物

131110-76-4 1676-81-9 2766-43-0

上下游产品

N-benzylidene-L-serine methyl ester methyl (2S)-2-amino-3-hydroxypropanoate hydr°Chloride benzaldehyde benzyl bromidemethyl (2S,4S)-2-thiomethyl-2-oxo-3-benzyl-1,3,2-oxazaphospholidine-4-carboxylate methyl (2R,4S)-2-thiomethyl-2-oxo-3-benzyl-1,3,2-oxazaphospholidine-4-carboxylate methyl N-benzyl-N-(tert-butoxycarbonyl)-L-serinate Methyl (2S,4S)-2-Chloro-2-oxo-(syn)-3-benzyl-1,3,2-oxazaphospholidine-4-carboxylate

📜苯甲醛置于sodium Tetrahydroborate,Magnesium Sulfate,三乙胺体系中,用 甲醇,二氯甲烷 用作溶剂,化学反应 28.0H,反应生成L-N-苄基丝氨酸甲酯
参考文献:A Hypervalent Iodine-Mediated Spirocyclization Of 2-(4-Hydroxybenzamido)Acrylates-Unexpected Formation Of δ-Spirolactones
标题:A Hypervalent Iodine-Mediated Spirocyclization Of 2-(4-Hydroxybenzamido)Acrylates-Unexpected Formation Of δ-Spirolactones
摘要:在(S)-芳香酸的新总合成过程中,发现了一种新型的芳基-λ3-碘酸盐介导的氧化螺环化反应,适用于对位取代的酚衍生物.我们从易于获取的2-(4-羟基苯酰氨基)丙烯酸酯出发,成功构建了高达52%产率的螺环内酰胺.在不同的反应条件下,同样的前体经历了意想不到的氧化螺环化反应,生成了一种新型的δ-螺内酯,产率高达70%.
Doi:10.1039/c2Ob26815A

专利信息

专利号:EP-0631581-A1
优先权日:1992-03-16
标题 :Intermediates and a process for synthesis of tetrahydropteridine c6-stereoisomers, including (6s)-tetrahydrofolate and n5-formyl-(6s)-tetrhydrofolate

专利号:AU-3804193-A
优先权日:1992-03-16
标 题:Intermediates and a process for synthesis of tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolate and N5-formyl-(6S)-tetrhydrofolate