CAS: 104-28-9; Cinoxate

上下游产品

2-ethoxy-ethanol 3-(4'-methoxyphenyl)propenoic acid

📜乙二醇乙醚,4-甲氧基肉桂酸置于咪唑,Carboxylic Acid Reductase From Mycobacterium Marinum,5'-三磷酸腺苷,Magnesium Chloride体系中,用 Aq. Buffer 用作溶剂,化学反应 45.0H,以32%的收率获得西诺沙酯
参考文献:羧酸还原酶可以在水性环境中催化酯的合成
标题:羧酸还原酶可以在水性环境中催化酯的合成
摘要:大多数众所周知的催化酯化的酶都需要尽量减少水或活化底物的活性.这项工作报告了一种新的反应,该反应是由羧酸还原酶(car)催化的,该酶已知是利用atp,Mg 2+将多种羧酸转化为醛的酶.和nadph作为共同底物.当nadph被亲核醇替代时,来自海洋分枝杆菌的car可以在室温下在水性条件下催化酯化反应.尤其是在ph 10.0时,添加咪唑可显着提高酯的产生.与其他酯化酶(如酰基转移酶和脂肪酶)相比,Car在水性条件下的直接酯化反应中具有更高的酯化收率.证明了car催化酯化反应的可扩展性,可合成防晒霜中的活性成分cinoxate.Car酯化为高水分条件下的绿色酯化提供了一种新方法.
Doi:10.1002/anie.202013962

专利信息

专利号:US-7662401-B2
优先权日:2002-04-08
标 题 :Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase
发明人：MAHE YANN; MEYBECK ALAIN
权利人:OREAL
摘要:The present invention relates to the cosmetic or pharmaceutical use of an extract of a nonfruiting nonphotosynthetic filamentous bacterium in a composition containing a cosmetically or pharmaceutically acceptable medium, as an agent increasing the endogenous synthesis of superoxide dismutase, in particular for preventing and/or limiting the formation of free radicals and/or removing the free radicals present in cells; in addition, the invention relates to a composition comprising at least one extract of Vitreoscilla filiformis and lycopene.

专利号:US-4348525-A
优先权日:1981-04-09
标题 :Composition and a process for the preparation of [hydroxy(organosulfonyloxy)iodo]arenes and their use in a regiospecific synthesis of diaryliodonium salts
发明人：KOSER GERALD F; WETTACH RICHARD H
权利人:UNIV AKRON
摘要:[Hydroxy(organosulfonyloxy)iodo]arenes are synthesized in neutral organic solvents by the reaction of ring-substituted [hydroxy(organosulfonyloxy)iodo]benzenes with iodoarenes via ligand transfer. The produced compounds are reacted with (triorganosilyl) arenes or (trihalosilyl)arenes in neutral organic solvents to produce diaryliodonium salts. The diaryliodonium salt synthesis proceeds in regiospecific fashion, aryliodination occurring at the point of attachment of the silicon atom in the silylarenes.

专利号:US-3694464-A
优先权日:1968-07-10
标 题 :PREPARATION OF 1-ACETOXY-3-(ALKYL)-6,6,9-TRIMETHYL-7,8,9,10-TETRAHYDRO-6H-DIBENZO{8 b,d{9 {0 PYRAN ISOMERS
发明人：AARON HERBERT S; FERGUSON CLYDE PARKER JR
权利人:US ARMY
摘要:A novel process and novel intermediates in the synthesis of the novel optically-active isomers of 1-acetoxy-3(alkyl)-9-methyl7,8,9,10-tetrahydro-6H-dibenzo (b,d)pyran as incapacitating agents. Those intermediates are prepared by reducing a mixture comprising a ketone, an alcohol and borohydride to the carbinol, treating said carbinol with a trihalide and converting the trihalide product to a malonic ester, hydrolyzing said ester and separating the aqueous phase, acidifying said aqueous phase results in the preparation of an isomeric mixture of alkyldialkoxyhydrocinnamic acid.

专利号:EP-1354593-B1
优先权日:2002-04-08
标题 :use of an extract of a non-photosynthetic filamentous bacterium as an agent for enhancing the endogenous synthesis of superoxide dismutase
发明人：MAHE YANN; MEYBECK ALAIN
权利人:OREAL
摘要:Promoting endogenous production of superoxide dismutase (SOD) comprises the use of an extract (I) of non-photosynthetic, non-fruiting filamentous bacteria in cosmetic, dermatological or pharmaceutical applications. Use of an extract (I) of non-photosynthetic, non-fruiting filamentous bacteria: (1) in a composition based on a cosmetic medium, as an agent for promoting endogenous production of superoxide dismutase (SOD); or (2) for production of a pharmaceutical or dermatological composition for promoting endogenous production of SOD. Independent claim are also included for: (1) a composition comprising a physiological medium containing Vitreoscilla filliformis extract (Ia) and lycopene (specifically at 0.000000001-0.1 wt. %) or a compound having catalase activity and/or a compound having peroxidase activity; and (2) cosmetic treatment methods for treating loss of firmness and/or elasticity of the skin or for treating skin exposed to sunlight, involving application of compositions containing (Ia).

专利号:US-2003224077-A1
优先权日:2002-04-08
标 题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase

专利号:US-2007237746-A1
优先权日:2002-04-08
标题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase