CAS: 102-49-8; 3,4-Dichlorobenzylamine

相似化合物

2670-38-4 4152-90-3 39989-43-0

上下游产品

CAS号102-47-6 3,4-二氯氯苄 | CAS号108011-92-3 N-(3,4-dichloro... | CAS号5331-92-0 3,4-二氯苯甲醛肟 | CAS号6287-38-3 3,4-二氯苯甲醛 | CAS号540-69-2 甲酸铵 | CAS号20907-55-5 3,5-dibromo-N-[... | CAS号23749-87-3 Thiourea,N,N'-b... | CAS号18967-42-5 3,4-二氯苄基异硫氰酸酯 | CAS号6574-99-8 3,4-二氯苯甲腈 | CAS号133338-58-6 N(2)-(3,4-dichl... | CAS号146579-22-8 N-[(3,4-dichlor... | CAS号19752-09-1 异氰酸3,4-二氯苯甲酯 | CAS号36458-26-1 3,4-Cl2C6H3CH2N... | CAS号554-68-7 三乙胺盐酸盐 | CAS号73728-65-1 N-(2-Ethoxyethy...

3,4-二氯氯苄置于potassium Carbonate,一水合肼体系中,用 乙醇,N,N-二甲基甲酰胺 用作溶剂,化学反应生成3,4-二氯苄胺
参考文献:N-取代的磷酰胺酸酯的合成,作为"反向"磷霉素类似物
标题:N-取代的磷酰胺酸酯的合成,作为"反向"磷霉素类似物
摘要:从取代的苄胺开始,已经开发了一种有效的合成途径,可以合成一系列新型的"反向"磷霉素类似物.在这些类似物中,膦酰胺异羟肟酸酯部分被颠倒,与膦酸酯部分相邻的四面体亚甲基碳被带有不同苄基的氮原子取代.所得的膦酸酯被设计为潜在的抗疟"前药".
Doi:10.1016/j.Tet.2019.02.003

专利信息

专利号:US-8735391-B2
优先权日:2008-09-26
标 题 :Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods
发明人：AUBE JEFFREY; ROTH BRYAN L; GHOSH PARTHA; FRANKOWSKI KEVIN J
权利人:AUBE JEFFREY; ROTH BRYAN L; GHOSH PARTHA; FRANKOWSKI KEVIN J; UNIV KANSAS
摘要:A functionalized polycyclic compound can have a structure of Formula 1 or salt, prodrug, analog, or derivative thereof, which compound can be prepared by providing a diene; reacting the diene with a dienophile under sufficient conditions for a combined Diels-Alder/acylation reaction so as to provide a polycyclic compound having a carboxylic acid; and coupling the carboxylic acid with an amine-containing compound or a hydroxyl-containing compound so as to form an amide or an ester and producing a compound having a structure of Formula 1. The compound can be used for modulating an opioid receptor, which can be conducted by administering to an opioid receptor a functionalized polycyclic compound as described herein in an effective amount to modulate the functionality of the opioid receptor. Such opioid modulation can provide a biological benefit to a subject.

专利号:US-4388310-A
优先权日:1982-03-01
标 题:6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
发明人：CHRISTENSEN BURTON G; DININNO FRANK P; MUTHARD DAVID A; RATCLIFFE RONALD W
权利人:MERCK & CO INC
摘要:Disclosed are 6-amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids (I) which are useful as antibiotics and as intermediates in the synthesis of substituted pen-2-em-3-carboxylic acids: I wherein: R1 is H or acyl; R2 is hydrogen or methoxyl; R3 is alkyl having from 1-6 carbon atoms; phenylalkyl having 7-12 carbon atoms; and cycloalkyl having 3-6 carbon atoms; and R4 is hydrogen, a removable protecting group or a pharmaceutically acceptable salt or ester moiety.

专利号:US-2005137391-A1
优先权日:1999-02-04
标题 :Process for the synthesis of oligomeric compounds

专利号:US-7186822-B2
优先权日:1999-02-04
标 题 :Process for the synthesis of oligomeric compounds

专利号:US-7199236-B2
优先权日:1999-02-04
标 题 :Process for the synthesis of oligomeric compounds

专利号:US-7227016-B2
优先权日:1999-02-04
标 题 :Process for the synthesis of oligomeric compounds
发明人：RAVIKUMAR VASULINGA T; MANOHARAN MUTHIAH; CAPALDI DANIEL C; KROTZ ACHIM; COLE DOUGLAS L; GUZAEV ANDREI
权利人:ISIS PHARMACEUTICALS INC
摘要:Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants.