CAS: 10030-73-6; (E)-Hexadec-9-Enoic Acid

该化合物是一种脂肪酸,其特点是长碳链,在第九碳原子上是一种双联,是一种不饱和的脂肪酸,与分子分子式C16H30O2有二分之一的分子式C16H30O2,该化合物通常以少量的脂肪和油质找到,特别是在工业应用和研究方面.棕榈酸在研究跨脂肪中具有显著作用,因为它可以影响脂肪的物理特性,如熔点和流体.它存在于食品中,由于跨脂肪对心血管健康的潜在影响,引起健康问题.在溶性方面,棕榈酸一般在有机溶剂中溶解,但水中的溶性有限.该化合物可以通过各种化学过程合成,包括棕榈油酸的氢化.

结构式图片

上下游产品

棕榈油酸 Palmitoleic Acid 373-49-9
9-Hexadecenoic Acid Methyl Ester 3913-63-1
9,10-二羟基十六烷酸 9,10-Dihydroxy-Hexadecanoic Acid 29242-09-9

合成工艺路线路线简述

  • 合成目标产物 Palmitelaidic Acid 主要起始原料 Ethyl Heptanoate
  • (文献来源)合成步骤主要原料 Ethyl Heptanoate
📜15-Ethoxy-Pentadecane-7,8-Diol 反应生成(9E)-9-十六烯酸
参考文献:Baudart,1945,Vol. 29,P. 75
标题:Baudart,1945,Vol. 29,P. 75

海关参考信息

专利信息


专利号:US-2009099061-A1
优先权日:2006-01-27
标 题:Synthesis of carotenoid analogs or derivatives with improved antioxidant characteristics
发明人:FOSS BENTE J; NADOLSKI GEOFFRY T; LOCKWOOD SAMUEL F
权利人:FOSS BENTE J; NADOLSKI GEOFFRY T; LOCKWOOD SAMUEL F
摘要:A method is described for synthesizing and administering carotenoid compounds with improved antioxidant characteristics. In some embodiments, extension or improvement of conjugation may be employed in structural modification of carotenoids. In other embodiments, reduction of ring/chain steric hindrance may improve the lambda max, and hence, the overall antioxidant capability, of particular compounds. In other embodiments, introduction and/or increase in synthetic handles for conjugation may improve the stoichiometric ratios of conjugating moieties to the polyene backbone. The methods may be used to improve natural and/or synthetic compounds for medicinal application in the treatment of disease.

专利号:US-9453037-B2
优先权日:2011-07-28
标 题 :Methylphenidate-prodrugs, processes of making and using the same
发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
权利人:KEMPHARM INC; KEMPHARM INC
摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

专利号:US-2012282652-A1
优先权日:2011-02-28
标题 :Preparation of peptide mixtures by protease catalysis designed to provide useful biological and physical properties
发明人:GROSS RICHARD A; VISWANATHAN KODANDARAMAN; QIN XU
权利人:GROSS RICHARD A; VISWANATHAN KODANDARAMAN; QIN XU; POLITECHNIC INST UNIV NEW YORK
摘要:A process for preparing unique peptide mixtures with a broad range of uses using combinations of natural and non-natural amino acid alkyl ester monomers and specific combinations of these monomers as dimers, trimers and higher oligomers selected from the large group of structural motifs that lead to useful physical and/or biological properties and that have been or may be identified from solid state peptide synthesis, isolation of peptides from natural sources, and production of peptides by recombinant DNA methods, or identification of peptides by recombinant methods such as phage display, the method of peptide synthesis comprising a) admixing one or more natural and non-natural amino acid alkyl ester monomer, dimer, trimer and higher oligomers with one or more proteases in a reaction medium; b) heating the mixture to between about 5° C. to about 90° C. for between 5 minutes and 24 hours; and c) recovering the formed oligopeptide.

专利号:US-2014256904-A1
优先权日:2011-08-15
标 题:Biotechnological synthesis process of omega-functionalized carbon acids and carbon acid esters from simple carbon sources
发明人:SCHAFFER STEFFEN; DECKER NICOLE; GIELEN JASMIN; HAEGER HARALD; HAAS THOMAS; POETTER MARKUS; HENNEMANN HANS-GEORG; WESSEL MIRJA; VOLLAND MICHAEL
权利人:SCHAFFER STEFFEN; DECKER NICOLE; GIELEN JASMIN; HAEGER HARALD; HAAS THOMAS; POETTER MARKUS; HENNEMANN HANS-GEORG; WESSEL MIRJA; VOLLAND MICHAEL; EVONIK DEGUSSA GMBH
摘要:The subject of the invention is a biotechnological process for the production of ω-functionalized carboxylic acids and of ω-functionalized carboxylate esters from simple carbon sources.

专利号:US-9585890-B2
优先权日:2012-09-26
标题 :Modulators of androgen synthesis
发明人:DILLY SUZANNE; STOLOFF GREGORY; TAYLOR PAUL
权利人:TANGENT REPROFILING LTD
摘要:The present specification discloses compositions comprising at least one therapeutic compound capable of modulating androgen production and methods and uses for treating a disorder associated with androgen production using such compositions and/or compounds.

专利号:US-9808462-B2
优先权日:2012-09-26
标题 :Modulators of androgen synthesis
发明人:DILLY SUZANNE; STOLOFF GREGORY; TAYLOR PAUL
权利人:TANGENT REPROFILING LTD
摘要:The present specification discloses compositions comprising at least one therapeutic compound capable of modulating androgen production and methods and uses for treating a disorder associated with androgen production using such compositions and/or compounds.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Nolte, J. C.; Urlacher, V. B., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 29.
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
参考文献:10.1007/bf02535836
摘要:Mohamed HF, Andreone TL, Dryer RL. Mitochondrial metabolism of (D,L)-threo-9, 10-dibromo plamitic acid. Lipids. 1980 Apr;15(4):255–62. doi: 10.1007/bf02535836.
参考文献:10.1007/s10886-008-9456-9
摘要:Urbanová K, Cahlíková L, Hovorka O, Ptáček V, Valterová I. Age-Dependent Changes in the Chemistry of Exocrine Glands of Bombus terrestris Queens. Journal of Chemical Ecology. 2008 Mar 28;34(4):458–66. doi: 10.1007/s10886-008-9456-9.
参考文献:10.1186/gm115
摘要:Roberts LD, Hassall DG, Winegar DA, Haselden JN, Nicholls AW, Griffin JL. Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse. Genome Med. 2009 Dec 07;1(12):115.
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