CAS: 6933-47-7; Methyl 4-Amino-2-Methylbenzoate

该化合物是一种苯甲酸酯衍生物,其成分为氨基氨基氨基酯和芳香环上的甲基替代物,该化合物主要用作有机合成的中间体,特别是在生产药品,农用化学品和特殊化学品方面,其结构特性,包括电子捐赠氨基氨基组和酯功能,使它成为进一步功能化的多用途构件.该化合物在标准条件下具有良好稳定性,与一系列合成变异相容.其定义明确的再活性和纯度使其适合研究和工业工艺的精确应用.建议适当的处理和储存保持其完整性.

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欧盟法规

ECHA物质C&L通报

上下游产品

4-氨基-2-甲基苯甲酸 4-Amino-2-Methylbenzoic Acid 2486-75-1
4-乙酰基氨基-2-甲基-苯甲酸甲酯 Methyl 4-Acetamido-2-Methylbenzoate 91133-71-0
2-甲基-4-硝基苯甲酸甲酯 Methyl 2-Methyl-4-Nitrobenzoate 62621-09-4
4-乙酰氨基-2-甲基苯甲酸 4-Acetamido-2-Methylbenzoic Acid 103204-69-9

合成工艺路线路线简述

    📜4-乙酰基氨基-2-甲基-苯甲酸甲酯置于盐酸,甲醇,水体系中,化学反应 2.0H,反应生成 4-氨基-2-甲基苯甲酸甲酯
    参考文献:Wo2007/144379
    标题:Wo2007/144379

    海关参考信息

    专利信息


    专利号:US-2024092821-A1
    优先权日:2020-03-31
    标题:Synthesis of oligonucleotides and related compounds
    发明人:ZHONG MINGHONG; JIN YI; GALA DINESH; PRHAVC MARIJA
    权利人:JANSSEN BIOPHARMA INC
    摘要:Methods of synthesizing oligonucleotides via new intermediates on a cleavable support having an azidomethyl moiety are disclosed. The method comprises multiple reaction cycles, each of which comprises sequential coupling a nucleoside or oligonucleotide subunit on a cleavable support having an azidomethyl moiety and a nucleoside phosphoramidite or an oligonucleotide phosphoramidite, capping, oxidation/thiolation and deblocking; followed by orthogonal cleavage of the azidomethyl support while keeping all other protecting groups intact. The method can be used in combination with a support moiety for either solid phase or liquid phase oligo synthesis. The soluble support facilitates homogeneous reactions and efficient separations by simple precipitation. The methods also provide novel intermediates useful in the synthesis of oligonucleotide conjugates.

    专利号:CN-115843299-A
    优先权日:2020-03-31
    标 题 :Synthesis of oligonucleotides and related compounds

    专利号:IL-296862-A
    优先权日:2020-03-31
    标 题:Synthesis of oligonucleotides and related compounds

    专利号:AU-2021247043-A1
    优先权日:2020-03-31
    标题:Synthesis of oligonucleotides and related compounds

    专利号:KR-20220161436-A
    优先权日:2020-03-31
    标 题 :Synthesis of oligonucleotides and related compounds

    专利号:EP-4126894-A1
    优先权日:2020-03-31
    标题:Synthesis of oligonucleotides and related compounds

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:A. de Courville. Compt. Rend., C 262, 1196 (1966).
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