CAS: 6283-24-5; Acetyloxy-(4-Aminophenyl)Mercury

上下游产品

mercury(II) diacetate aniline4,4'-diaminobenzophenone p,p'-diaminobiphenyl p-aminoiodobenzene 1-methyl-3-[N-(p-iodophenyl)carbamoyl]-1,4-dihydropyridine

专利信息

专利号:US-12129222-B2
优先权日:2016-08-11
标题:Production of bitter principle derivatives
发明人：WYRWA RALF; RODE CLAUDIA; SEEMANN THOMAS; MEINEL LORENZ; RITZER JENNIFER; SCHNABELRAUCH MATTHIAS
权利人:UNIV WUERZBURG J MAXIMILIANS; JULIUS MAXIMILIANS UNIV
摘要:It is an object of the present invention to introduce carboxylic acid-functionalities suitable for coupling into the denatonium structure by means of simple synthesis, namely the synthesis of bitter principle derivatives based on the denatonium structure according to formula 1:For example, according to the invention, lidocaine derivatives may be reacted with carboxylated benzyl halogenides. The carboxylated denatonium derivatives of the present invention are especially applied in medicine, biology, medical engineering as well as cosmetics, the pharmaceutical, chemical, and foodstuff industry.

专利号:US-5856356-A
优先权日:1996-06-17
标题:Use of strontium salts and pharmaceutical compositions thereof for the treatment of arthrosis
发明人：TSOUDEROS YANNIS; DELOFFRE PASCALE; WIERZBICKI MICHEL
权利人:ADIR
摘要:The invention relates to the use of strontium salts and pharmaceutical compositions thereof for the treatment of arthrosis through stimulation of the synthesis of proteoglycans and type II collagen by chondrocytes.

专利号:US-10934343-B2
优先权日:2016-05-13
标 题 :Polypeptide derived from tropoelastin and biocompatible material comprising same
发明人：DEBRET ROMAIN; FAYE CLÉMENT; SOHIER JÉRÔME; SOMMER PASCAL
权利人:CENTRE NAT RECH SCIENT; UNIV CLAUDE BERNARD LYON
摘要:The present invention provides a tropoelastin-derived polypeptide and an elastic composite biocompatible material comprising the polypeptide. The object of the invention is also a method for the synthesis of such a biocompatible material, a cell culture support comprising such a biocompatible material and the use of this material, in particular in the biological and medical field, in particular for cell culture and tissue regeneration.

专利号:US-6458822-B2
优先权日:2000-03-13
标题 :2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases
发明人：ROBINSON RALPH P; LAIRD ELLEN R
权利人:PFIZER
摘要:The present invention relates to a compound of the formula n wherein R 1 , R 2 , R 3 and R 4 are as defined above, and pharmaceutically acceptable salts and solvates thereof, that are useful, for example, as matrix metalloproteinase inhibitors. The present invention is also directed to pharmaceutical compositions comprising such compounds and methods of treatment for diseases such as osteoarthritis, rheumatoid arthritis, cancer, osteoporosis, tissue ulceration, restinosis, periodontal disease, inflammation, epidermolysis bullosa, scleritis, stroke, Alzheimer's disease, and the like, characterized by inappropriate matrix metalloproteinase activity. Processes for the synthesis of compounds of formula (I) are also disclosed.

专利号:US-9115212-B2
优先权日:2012-02-01
标题 :Bifunctional peptide
发明人：HORNEBECK WILLIAM; ATTIA JOAN; LORIMIER SANDRINE; ANTONICELLI FRANK
权利人:REGENTIS INTERNAT; UNIV REIMS CHAMPAGNE ARDENNE; CENTRE NAT RECH SCIENT
摘要:The bifunctional peptide is capable of activating collagen synthesis and inhibiting the production of matrix metallo-proteinases. The peptide has a sequence including three peptide parts A, B and C. The first peptide part A corresponds to a hexapeptide repeated at least three times, the part A being capable of bonding to a receptor elastin-binding protein in order to stimulate collagen synthesis. The second peptide part B corresponds to a tetrapeptide capable of acting as a competitive inhibitor of urokinase protease and of being cleaved by said protease. The third peptide part C corresponds to a tripeptide occupying at least one active site of the matrix metallo-proteinases in order to enable inhibition of the proteinases. The present invention further concerns a cosmetic and/or pharmaceutical composition incorporating the bifunctional peptide.

专利号:US-2003087863-A1
优先权日:2001-06-28
标 题:Methods for diagnosing and treating a disease mediated by decreased MMP-2 function
发明人：MARTIGNETTI JOHN A; DESNICK ROBERT J
权利人:SINAI SCHOOL MEDICINE
摘要:The present invention relates to a method for the prevention or treatment of a disease mediated by decreased MMP-2 function. This may result from an aberrant interaction of molecules that stimulate or inhibit MMP-2 protein synthesis, stability, or function, as well as from mutations in the coding or regulatory regions of the gene encoding MMP-2. The invention also provides a method for identifying a substance useful in this context. It further contemplates a method for diagnosing such a disease.