CAS: 5815-08-7; Tert-Butoxy Bis(Dimethylamino)Methane

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CAS号865-47-4 叔丁醇钾 | CAS号2013-91-4 [(dimethylamino... | CAS号3218-35-7 N,N,N',N'-Tetra... | CAS号5762-56-1 三(二甲氨基)甲烷 | CAS号36805-97-7 N,N-二甲基甲酰胺二叔丁基缩醛 | CAS号2214-82-6 bis(dimethylami... | CAS号36805-97-7 N,N-二甲基甲酰胺二叔丁基缩醛 | CAS号143547-74-4 5-二苯甲基-1H-吡唑 | CAS号924-99-2 3-(二甲氨基)丙烯酸乙酯 | CAS号124-40-3 二甲胺 | CAS号75-65-0 叔丁醇 | CAS号20973-83-5 N,N-dimethyl-2-... | CAS号2214-82-6 bis(dimethylami... | CAS号21203-79-2 2-甲基-4-苯基嘧啶 | CAS号20488-07-7 ethyl 3-(dimeth... | CAS号27159-75-7 N'-benzyl-N,N-d...

Potassium Tert-Butylate,N,N,N',N'-Tetramethylformamidinium Hexafluorophosphate 以 四氢呋喃 作为反应溶剂,化学反应 4.5H,反应生成 Bredereck 试剂
参考文献:Method Of Preparing Aza-Pyridone Compounds
标题:Method Of Preparing Aza-Pyridone Compounds
摘要:本文披露了一种获取氮杂吡啶酮化合物的方法,该方法可用于改善和/或治疗疾病和/或病况,包括流感病毒感染.

专利信息

专利号:US-11274081-B2
优先权日:2016-05-30
标 题:Process for the synthesis of ivacaftor
发明人：REDDY DUMBALA SRINIVASA; KULKARNI AMOL ARVIND; NATARAJAN VASUDEVAN; SHARMA MRITYUNJAY KESHAVPRASAD
权利人:COUNCIL SCIENT IND RES
摘要:The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.

专利号:US-4376207-A
优先权日:1980-08-18
标 题 :Chiral synthesis of amino sugars
发明人：USKOKOVIC MILAN R; WOVKULICH PETER M
权利人:HOFFMANN LA ROCHE
摘要:A simple and economic chiral synthesis of optically active methyl L-acosaminide and methyl L-daunosaminide from propenyl acetate, said methyl L-acosaminide and methyl L-daunosaminide being coupling agents for the production of known antitumor agents.

专利号:US-4324726-A
优先权日:1979-07-25
标题 :Chiral synthesis of amino sugars
发明人：USKOKOVIC MILAN R; WOVKULICH PETER M
权利人:HOFFMANN LA ROCHE
摘要:A simple and economic chiral synthesis of optically active methyl L-acosaminide and methyl L-daunosaminide from propenyl acetate, said methyl L-acosaminide and methyl L-daunosaminide being coupling agents for the production of known antitumor agents.

专利号:US-2025066296-A1
优先权日:2021-12-14
标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof
发明人：HASHIMOTO AKIHIRO; PHADKE AVINASH; RAI U SANKAPPA; CHANDRAN PRABU
权利人:ALEXION PHARMA INC
摘要:The present disclosure provides methods for the synthesis of complement factor D inhibitors and intermediates thereof.

专利号:US-4414402-A
优先权日:1981-12-02
标 题:[2S-(2β,2S*, 3β)]-3-Aminotetrahydro-5-methoxy-α-methyl-2-furanmethanol, an intermediate in the chiral synthesis of amino sugars
发明人：USKOKOVIC MILAN R; WOVKULICH PETER M
权利人:HOFFMANN LA ROCHE
摘要:A simple and economic chiral synthesis of optically active methyl L-acosaminide and methyl L-daunosaminide from propenyl acetate, said methyl L-acosaminide and methyl L-daunosaminide being coupling agents for the production of known antitumor agents.

专利号:WO-2012100419-A1
优先权日:2011-01-26
标 题 :Process for synthesis of 3-(n,n-disubstituted-amino)-2- substituted acrylate
发明人：GU HAINING; LI XIAOLING; ZHANG PENGFEI; ZHANG XIKUN; CHEN LIANG
权利人:HANGZHOU GREAT FOREST BIOMEDICAL LTD; GU HAINING; LI XIAOLING; ZHANG PENGFEI; ZHANG XIKUN; CHEN LIANG
摘要:Disclosed is a process for synthesis of 3-(N,N-disubstituted-amino)-2-substituted acrylate, which comprises carrying out amine-substitution reaction and elimination reaction for 2-substituted formylacetate alkali metal salt represented by formula (III) and amine complex represented by formula (II) in organic solvent 1 to obtain 3-(N,N-disubstituted-amino)-2-substituted acrylate represented by formula (I). The process uses N,N-disubstituted amine and carbon dioxide, or a liquid complex obtained by N,N-disubstituted amine and carbon dioxide as raw material, thereby it doesn't produce a side product influencing environment. The process has the advantages of reacting simply and operating easily.