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2-氯甲基苯并咪唑置于水体系中,化学反应生成 2-羟甲基苯并咪唑
参考文献:The Allylic Character Of 2-(α-Chloroalkyl)-Benzimidazoles1
标题:The Allylic Character Of 2-(α-Chloroalkyl)-Benzimidazoles1
摘要:
DOI:10.1021/ja01250A019

专利信息

专利号:WO-2012011793-A1
优先权日:2010-07-19
标 题:Surfactants for the modification of clay, method of synthesis and the nanocomposites produced
发明人：BOUSMINA MOSTAPHA; ESSASSI EL MOKHTAR; BOUHFID RACHID; ENNAJIH HAMID
权利人:MOROCCAN FOUNDATION FOR ADVANCED SCIENCE INNOVATION & RES MASCIR; BOUSMINA MOSTAPHA; ESSASSI EL MOKHTAR; BOUHFID RACHID; ENNAJIH HAMID
摘要:A surfactant, a clay modified with a surfactant, the preparation processes described, and also the polymer nanocomposites produced from the modified clay. The surfactant of formula (I), characterized in that: R 1 : C n H 2n+1 with n = 1-20; C n H 2n -OH with n = 1-4; or C n H 2n -SO 3 H with n = 1-4; R 2 : C n H 2n+1 with n = 0-20; C n H 2n -OH with n = 1-4; or C n H 2n -SH with n = 1-4; R 3 : C n H 2n+1 with n = 1-20; C n H 2n -OH with n = 1-4; or C n H 2n -SO 3 H with n = 1-4; R 5 : H, Cl, CH 3 , NO 2 , CN, SO 3 H, Br, NH 2 or CO 2 H; R 6 : H, Cl, CH 3 , NO 2 , CN, SO 3 H, Br, NH 2 or CO 2 H; R 7 : H, Cl, CH 3 , NO 2 , CN, SO 3 H, Br, NH 2 or CO 2 H; R 8 : H, Cl, CH 3 , NO 2 , CN, SO 3 H, Br, NH 2 or CO 2 H; and X - : Cl - , Br - , I - , CH 3 SO 4 n - , C 6 H 5 SO 3 n - , or CH 3 COC - .

专利号:WO-2024216075-A1
优先权日:2023-04-13
标题 :Synthesis of mavorixafor and intermediates thereof
发明人：SEKIRNIK ANGELINA ROBERTA; TAVERAS ART; GAO FENG; ZHAO ZHIGANG
权利人:X4 PHARMACEUTICALS INC
摘要:The present invention relates to methods for synthesizing C-X-C receptor type 4 (CXCR4) inhibitor mavorixafor and to intermediates thereto.

专利号:WO-2024216114-A1
优先权日:2023-04-13
标题 :Synthesis of mavorixafor and intermediates thereof
发明人：SEKIRNIK ANGELINA ROBERTA; TAVERAS ART; GAO FENG; ZHAO ZHIGANG
权利人:X4 PHARMACEUTICALS INC
摘要:The present invention relates to methods for synthesizing C-X-C receptor type 4 (CXCR4) inhibitor mavorixafor and to intermediates thereto.

专利号:WO-2024216095-A1
优先权日:2023-04-13
标 题 :Synthesis of mavorixafor and intermediates thereof
发明人：SEKIRNIK ANGELINA ROBERTA; TAVERAS ART; HANSELMANN ROGER; GAO FENG; ZHAO ZHIGANG
权利人:X4 PHARMACEUTICALS INC
摘要:The present invention relates to methods for synthesizing the C-X-C receptor type 4 (CXCR4) inhibitor mavorixafor and to intermediates thereto.