CAS: 26734-09-8; 3-Amino-2,2-Dimethyl-1-Propanol

该化合物是有机化合物,其特征是氨基氨基化合物和氢氧基化合物,使其成为氨基酒精;其结构特征是第三级碳原子,该原子与两个甲基组和氢基化合物相连,具有独特的特性;该化合物一般是无色的,可粉黄,具有典型的有矿泉味;由于氢氧组,可溶于水中,这增加了其极度;氨基混合物可参与氢的结合,影响其反应和与其他物质的互动;3-Amino-2-2-2-二甲基-1-丙醇经常用于各种用途,包括作为有机合成的建筑块,表面活性剂的配制和制药生产的潜在中间体;它作为核素的特性,在化学反应中,特别是在合成较复杂的分子方面,其作用非常宝贵;在处理和储存方面,应参考安全数据,如任何化学物质.

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184357-44-6 177269-37-3 80253-38-9

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2,2-dimethyl-3-hydroxypropionaldehyde bis-(3-hydroxy-2,2-dimethyl-propylidene)-hydrazine 2-cyano-2-methyl-propionic acid ethyl ester 3-azido-2,2-dimethyl-1-propanol 2,2-dimethyltrimethylenecyclourethane N-(3-hydroxy-2,2-dimethylpropyl)benzamide 2-(bis-(2-chloroethyl)amino)-2-oxo-5,5-dimethyl-1,3,2-oxazaphosphorinane 5,5-Dimethyl-2-phenoxy-[1,3,2]oxazaphosphinane 2-oxide

合成工艺路线路线简述

    📜2,2-二甲基-3-羟基丙醛置于甲醇,氨,镍体系中,化学反应生成3-氨基-2,2-二甲基-1-丙醇
    参考文献:De726387
    标题:De726387

    海关参考信息

    专利信息


    专利号:WO-0140193-A1
    优先权日:1999-12-03
    标题:Method for the synthesis of pyrazolines
    发明人:BOLDI ARMEN M
    权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
    摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

    专利号:US-2002103381-A1
    优先权日:2000-11-30
    标 题 :Method for the synthesis of pyrazolines
    发明人:BOLDI ARMEN M
    摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

    专利号:EP-0830136-B1
    优先权日:1995-03-07
    标 题:New cryptophycins from synthesis
    发明人:MOORE RICHARD E; TIUS MARCUS A; BARROW RUSSELL A; LIANG JIAN; CORBETT THOMAS H; VALERIOTE FREDERICK A; HEMSCHEIDT THOMAS K; GOLAKOTI TRIMURTULU
    权利人:UNIV HAWAII; UNIV WAYNE STATE
    摘要:Novel cryptophycin compounds are disclosed, together with methods of producing cryptophycins by total synthesis and methods for the use of such cryptophycins in pharmaceuticals to inhibit the proliferation of mammalian cells and to treat neoplasia.

    专利号:US-6013626-A
    优先权日:1993-12-21
    标题 :Cryptophycins from synthesis
    发明人:MOORE RICHARD E; TIUS MARCUS A; BARROW RUSSELL A; LIANG JIAN; CORBETT THOMAS H; VALERIOTE FREDERICK A; GOLAKOTI TRIMURTULU; HEMSCHEIDT THOMAS K
    权利人:UNIV HAWAII; UNIV WAYNE STATE
    摘要:A cryptophycin compound is provided having the structure: ##STR1## Further provided are methods of producing cryptophycins by total synthesis and methods of using cryptophycins in pharmaceuticals. It is a further object of this invention to use cryptophycins to inhibit the proliferation of mammalian cells. Moreover, methods of using cryptophycins to treat neoplasia is also provided.

    专利号:EP-0844261-A1
    优先权日:1996-11-21
    标题:Dispersions containing polyurethanes with carbonyl groups in ketone function
    发明人:KOKEL NICOLAS DR; GULBINS ERICH DR; RAU MARIA GYOPAR DR; FISCHER GERHARD
    权利人:BASF AG
    摘要:R 1 , R 2 , R 3 jeweils Wasserstoff, C 1 - bis C 24 -Alkyl oder C 6 - bisnC 24 -Alkenyl R 4 Wasserstoff R 5 , R 6 a) gemeinsam C 4 - bis C 10 -Alkandiyl, b) jeweils C 2 - bis C 10 -Alkyl, C 5 - bis C 8 -Cycloalkylnoder C 7 - bis C 20 -Aralkyl, c) jeweils ein hydroxylterminiertes Poly-(C 2 - bisnC 4 -alkylenoxid), oder d) ein Rest R 5 oder R 6 die unter (a) bis (c) angegebenenBedeutung und der andere Rest Wasserstoffnoder ein Rest der Formel IIn nin der X C 2 - bis C 6 -Alkandiyl bedeutet und R 7 gleichbedeutend ist mit R 5 oder R 6 mit der Ausnahme,ndaß R 7 nicht ein Rest der Formel II bedeutet, nwobei n die Reste R 5 und R 6 in jedem der Fälle (a) bis (d) insgesamtneine (1) an ein aliphatisches C-Atom gebundene Hydroxylgruppenntragen, gegebenenfalls der Rest R 5 und/oder R 6 1 oder 2 aromatischngebundene Hydroxylgruppen oder 1 Nitril-, tertiäre Amino-,nCarbonsäure- oder Sulfonsäuregruppe, die gegebenenfalls innForm ihrer Salze vorliegen, trägt, und die mittlere Funktionalität (F) aller Aufbaukomponenten desnPolyurethans (A), bezogen auf die Funktionalitäten, die beimnAufbau des Polyurethans (A) in einer Additionsreaktion miteinandernreagieren, 1,5 bis 2,2 beträgt. Aqueous dispersions containing a polyurethane (A) with structural units which differ from compounds of the formula (I) in which the substituents have the following meaning: R 1 , R 2 , R 3 in each case hydrogen, C 1 - to C 24 -alkyl or C 6 - to C 24 -alkenyl R 4 hydrogen R 5 , R 6 a) together C 4 - to C 10 -alkanediyl, b) in each case C 2 to C 10 alkyl, C 5 to C 8 cycloalkyl or C 7 to C 20 aralkyl, c) in each case a hydroxyl-terminated poly (C 2 - to C 4 -alkylene oxide), or d) a radical R 5 or R 6 has the meaning given under (a) to (c) and the other radical is hydrogen or a radical of the formula II in the X C 2 - to C 6 -alkanediyl means and R 7 is equivalent to R 5 or R 6 with the exception that R 7 does not represent a radical of the formula II, in which the radicals R 5 and R 6 in each of cases (a) to (d) carry a total of one (1) hydroxyl groups bonded to an aliphatic carbon atom, optionally the radical R 5 and / or R 6 carries 1 or 2 aromatically bound hydroxyl groups or 1 nitrile, tertiary amino, carboxylic acid or sulfonic acid group, which are optionally present in the form of their salts, and the average functionality (F) of all structural components of the polyurethane (A), based on the functionalities which react with one another during the synthesis of the polyurethane (A) in an addition reaction, is 1.5 to 2.2.

    专利号:US-2017266326-A1
    优先权日:2011-09-09
    标题:Compositions, methods, and systems for the synthesis and use of imaging agents

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    合成参考文献


    摘要:Braverman, S.; Cherkinsky, M.; Birsa, M. L., Science of Synthesis, (2005) 18, 192.
    摘要:Kantlehner, W., Science of Synthesis, (2006) 24, 358.
    摘要:Bingham, M. J.; Greaney, M. F., Science of Synthesis, (2008) 36, 1015.
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