CAS: 2566-29-2; H-Deg-Oh

相似化合物

92398-53-3 139937-99-8 218926-46-6

上下游产品

CAS号5455-34-5 5,5-二乙基海因 | CAS号74-96-4 溴乙烷 | CAS号56-40-6 甘氨酸 | CAS号189631-96-7 Butanoic acid,2... | CAS号75-03-6 碘乙烷 | CAS号96-22-0 3-戊酮 | CAS号34451-66-6 2-乙基-2-羟基丁腈 | CAS号22374-51-2 2-amino-2-ethyl... | CAS号5456-23-5 2-溴-2-乙基丁酸 | CAS号139578-94-2 Butanoic acid,2... | CAS号19792-52-0 2-氨基-2-丁基己醇 | CAS号139937-99-8 2-叔丁氧基羰基氨基-2-乙基-丁酸 | CAS号139578-94-2 Butanoic acid,2... | CAS号84310-95-2 2-ethyl-2-(phen... | CAS号5462-56-6 2-benzamido-2-e...

2-乙基-2-羟基丁腈置于乙醇,氨体系中,化学反应生成2-氨基-2-乙基丁酸
参考文献:Tiemann; Friedlaender,Chemische Berichte,1881,Vol. 14,P. 1973
标题:Tiemann; Friedlaender,Chemische Berichte,1881,Vol. 14,P. 1973

专利信息

专利号:EP-1198478-B1
优先权日:2000-07-31
标 题 :Somatostatin analogs and their use for the treatment of cancer
发明人：BURMAN ANAND C; PRASAD SUDHANAND; MUKHERJEE RAMA; JAGGI MANU; SINGH ANU T; MATHUR ARCHNA
权利人:DABUR RES FOUNDATION
摘要:The present invention encompasses novel peptides that are agonists to somatostatin and the use of the agonists for treatment of cancer. The invention particularly relates to the design and synthesis of novel analogs of somatostatin incorporating alpha , alpha -dialkylated amino acids in a site specific manner. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.

专利号:US-9453037-B2
优先权日:2011-07-28
标 题 :Methylphenidate-prodrugs, processes of making and using the same
发明人：GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
权利人:KEMPHARM INC; KEMPHARM INC
摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

专利号:US-6596692-B1
优先权日:2000-07-31
标 题 :Substance P analogs for the treatment of cancer
发明人：BURMAN ANAND C; PRASAD SUDHANAND; MUKHERJEE RAMA; JAGGI MANU; SINGH ANU T
权利人:DABUR RES FOUNDATION
摘要:The present invention encompasses novel synthetic peptide analogs that are antagonists to Substance P, substance P like peptides and related peptides and are useful for the treatment of cancer. The invention particularly relates to the design and synthesis of the novel substance P antagonist analogs incorporating alpha,alpha-dialkylated amino acids in a site specific manner. The invention encompasses methods for the generation of these peptides, compositions containing these peptides and pharmacological applications of these peptides specifically in the treatment and prevention of cancer.

专利号:US-6989371-B1
优先权日:1996-08-16
标 题:Bombesin analogs for treatment of cancer
发明人：BURMAN ANAND C; PRASAD SUDHANAND; MUKHERJEE RAMA; JAGGI MANU; SINGH ANU T; MATHUR ARCHNA
权利人:DABUR RES FOUNDATION
摘要:The present invention encompasses novel peptides that are antagonists to bombesin and bombesin like peptides and are useful in the treatment of cancer. The invention particularly relates to the design and synthesis of the novel peptides incorporating α,α-amino acids in a site specific manner. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6177087-B1
优先权日:1994-06-24
标 题:Non-antigenic amine derived polymers and polymer conjugates
发明人：GREENWALD RICHARD B; MARTINEZ ANTHONY; PENDRI ANNAPURNA
权利人:ENZON INC
摘要:Substantially non-antigenic polymers containing pI and/or pH optimum modulating moieties are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of activated polymers for conjugation with nucleophiles. Conjugates and methods of preparation and treatment with the conjugates are also disclosed.