CAS: 248593-16-0; Orysastrobin

该化合物是一种化学化合物,被归类为杀真菌剂,主要用于农业用途,以控制作物中各种真菌疾病;它属于Stubilin真菌杀菌剂类别,以其广泛频谱活动和抑制真菌中线粒体呼吸的行动方式而闻名;这个化合物的特点是它有能力对一系列病原体提供预防和治疗效应,使其有效保护作物免受疾病之害;Orysastrobin通常用作花生喷雾,在使用建议的准则时,因其对非目标生物,包括受益昆虫和哺乳动物的低毒性而受到估价;其化学结构包括有助于其生物活动和稳定性的具体功能组;与许多农业化学品一样,适当的处理和应用对于尽量减少环境影响和确保安全至关重要;

结构式图片

欧盟法规

C&L通报REACH预注册

合成工艺路线路线简述

    📜(E)-Methyl 2-(2-(Chloromethyl)Phenyl)-2-(Methoxyimino)Acetate,(2E,3Z)-Pentane-2,3,4-Trione O2,O3-Dimethyl Trioxime,甲胺置于sodium Methylate体系中,用 甲醇,N,N-二甲基甲酰胺 用作溶剂,化学反应 6.5H,以90.95%的收率获得
    参考文献: Method For Producing 2-Halogenomethylphenyl Acetic Acid Derivatives[fr] Procédé De Production De Dérivés D'Acide 2-Halogénométhylphénylacétique
    标题: Method For Producing 2-Halogenomethylphenyl Acetic Acid Derivatives[fr] Procédé De Production De Dérivés D'Acide 2-Halogénométhylphénylacétique

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-10906880-B2
    优先权日:2016-01-26
    标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
    发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
    权利人:UNIV NANKAI
    摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

    专利号:US-9968097-B2
    优先权日:2012-05-30
    标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
    发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
    权利人:BAYER CROPSCIENCE AG
    摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

    专利号:WO-2019218027-A1
    优先权日:2018-05-18
    标题:Core-shell particles
    发明人:MEANEY SHANE; TABOR RICHARD; FOLLINK BART
    权利人:UNIV MONASH
    摘要:The application relates to a core-shell particle having a) a cross-linked polyelectrolyte core, and b) a silica-based shell having covalently bound thereto one or more groups of formula –R–F, wherein R is an organic group and F is a functional moiety. The application also relates to a method of synthesis of a core-shell particle, the method comprising the steps of: a) providing a cross-linked polyelectrolyte core template, b) coating the core template with a silica-based shell, and c) introducing one or more groups of formula –R–F covalently bound to the silica-based shell, wherein R is an organic group and F is a functional moiety.

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    专利号:WO-2021074311-A1
    优先权日:2019-10-16
    标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)

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    主要参考文献


    1: Kwon CH, Lee YD, Im MH. Simultaneous determination of orysastrobin and its isomers in rice using HPLC-UV and LC-MS/MS. J Agric Food Chem. 2011 Oct 26;59(20):10826-30. doi: 10.1021/jf202228p. Epub 2011 Oct 4.
    113:161-167. doi: 10.1016/j.plaphy.2017.02.004. Epub 2017 Feb 7.
    48:152-65. doi: 10.1016/j.neuro.2015.03.013. Epub 2015 Apr 4. 45(4):223-229. doi: 10.1584/jpestics.D20-035.

    合成参考文献


    摘要:S69 | LUXPEST | Pesticide Screening List for Luxembourg | DOI:10.5281/zenodo.3862688
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