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专利信息
专利号:US-2005106689-A1
优先权日:2002-03-21
标 题:Synthesis of aminocrotonates
发明人:BRAUN MAX; BRAUKMUELLER SASKIA
权利人:SOLVAY FLUOR & DERIVATE
摘要:3-aminocrotonate compounds, e.g. diesters, which are substituted on the C-4 atom by at least two chlorine and/or fluorine atoms, are produced by reacting corresponding acetoacetate compounds with ammonia and primary and secondary amines while simultaneously or subsequently eliminating water. The reaction is carried out in the presence of onium salts formed from primary or secondary amines and carboxylic acids. Preferably, two phases are formed; one phase containing the crotonate compound product with a good degree of purity and the other phase containing the onium salt and water.
专利号:WO-2017072796-A1
优先权日:2015-10-30
标题 :2-pyridone based compounds useful as potential phosphodiesterase3a (pde3a)inhibitors and a process for the preparation thereof
发明人:KUMAR G JAGADEESH; MAHENDAR B; SAIDULU M; BANERJEE S K; RAO V JAYATHIRTHA
权利人:COUNCIL SCIENT IND RES
摘要:Formula A wherein X = COOCH 3 , COOC 2 H 5 , CN Y = Methyl, Phenyl R = alkyl, substituted phenyl, napthyl, furonyl, thiophenyl, substituted quinolinyl The present invention related to compounds of general FormulaA. The invention provides the synthesis of 2-pyridones useful as potential cardio tonic agents and a process for the preparation thereof.
专利号:CN-114989072-B
优先权日:2022-05-27
标 题 :Method for asymmetric catalytic synthesis of chiral 1, 4-dihydropyridine compound and application thereof
专利号:US-4358606-A
优先权日:1981-06-19
标 题:Esters of phenalkyloxycarbonylamino acids
发明人:LEE SHY-FUH; HENRICK CLIVE A
权利人:ZOECON CORP
摘要:Novel esters of phenylalkyloxy- or phenylalkylthioacylamino acids and pyridylalkyloxy- or pyridylalkylthioacylamino acids, synthesis thereof, intermediates therefor, and the use of said esters for the control of weeds.
专利号:US-5149814-A
优先权日:1987-09-30
标 题:Alkyl 2-benzylidene-4-(2-alkylimidazopyrid-1-yl) benzoylacetate esters as intermediate compounds
发明人:COOPER KELVIN; FRAY MICHAEL J; RICHARDSON KENNETH; STEELE JOHN
权利人:PFIZER
摘要:Intermediates useful in the synthesis of dihydropyridine platelet activating factor antagonists of the formula ##STR1## where R is phenyl or substituted phenyl; R 3 is lower alkyl; Y is 1,4-phenylene and X is 2-alkylimidazopyridyl.
专利号:EP-1532110-B1
优先权日:2002-07-01
标题 :Industrial process for the synthesis of isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridine dicarboxylate (nisoldipine)