CAS: 2039-87-4; 1-Chloro-2-Vinylbenzene

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CAS号54509-73-8 ethene | CAS号615-41-8 邻氯碘苯 | CAS号4026-05-5 3-叔丁基邻苯二酚 | CAS号865-47-4 叔丁醇钾 | CAS号105871-20-3 N-[2-(2-chlorop... | CAS号19819-95-5 2-氯苯乙醇 | CAS号60973-59-3 1-(dichlorometh... | CAS号2065-66-9 甲基三苯基碘化 | CAS号89-98-5 邻氯苯甲醛 | CAS号3867-18-3 2-乙烯基苯胺 | CAS号4251-63-2 2-氯苯乙醛 | CAS号89-98-5 邻氯苯甲醛 | CAS号62717-50-4 2-氯苯基环氧乙烷 | CAS号32345-65-6 (DL)-o-chloroph... | CAS号50-00-0 甲醛 | CAS号70599-64-3 Z-1-chloro-2-(2... | CAS号70599-65-4 (E)-1-chloro-2-... | CAS号4209-25-0 2-氯-1-(2-氯苯基)乙酮 | CAS号22014-99-9 1-丁基吲哚

1-(2-氯苯基)乙醇置于aluminum (III) Chloride,三苯基膦体系中,用 硝基甲烷 用作溶剂,化学反应 2.0H,以73%的收率获得2-氯苯乙烯
参考文献:路易斯碱辅助路易斯酸催化选择性烯烃形成,通过醇脱水和由 2-芳基-3,4-二氢吡喃合成 2-肉桂基-1,3-二羰基化合物
标题:路易斯碱辅助路易斯酸催化选择性烯烃形成,通过醇脱水和由 2-芳基-3,4-二氢吡喃合成 2-肉桂基-1,3-二羰基化合物
摘要:摘要 醇的酸催化脱水已广泛用于烯烃的合成.然而,当在脱水反应中用作底物时,活化的醇经常受到缺乏烯烃选择性的困扰.在这项工作中,通过与路易斯碱结合提高路易斯酸催化剂在活化醇脱水中的性能,可以显着改善反应体系.对反应机理的观察表明,路易斯碱组分可能改变了反应速率顺序.尽管主反应速率和副反应速率均降低,但在后一反应中观测到的影响明显更多.因此,提高了脱水反应的选择性.在此观察的基础上,一条合成 2-Cinnamyl-1 的新途径,
Doi:10.1016/s1872-2067(15)61084-1

专利信息

专利号:US-8669356-B2
优先权日:2009-10-21
标 题 :Linker and support for solid phase synthesis of nucleic acid
发明人：HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA
权利人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA; NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP
摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae n nwherein each symbol is as defined in the specification.

专利号:US-11512303-B2
优先权日:2017-05-27
标 题 :Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids
发明人：CHEN HAIBIN; BONG YONG KOY; XU QING; ZHOU AMENG; SHEN TIANRAN; YANG JIADONG; YANG ZHUHONG
权利人:ENZYMASTER NINGBO BIO ENG CO LTD
摘要:The present invention provides engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The engineered polypeptides disclosed in this invention were developed through directed evolution based on the ability of catalytic synthesis of (2S, 3R)-2-amino-3-hydroxy-3-(4-nitrophenyl) propanoic acid. The present disclosure also provides polynucleotides encoding engineered polypeptides, host cells capable of expressing engineered polypeptides, and methods of producing β-hydroxy-α-amino acids using engineered polypeptides. Compared to other processes of preparation, the use of the engineered polypeptides of the present invention for the preparation of β-hydroxy-α-amino acids results in high purity of the desired stereoisomers, mild reaction conditions, low pollution and low energy consumption. So, it has good industrial application prospects.

专利号:US-11725070-B2
优先权日:2018-05-09
标 题:Polymerization process for the synthesis of vinyl aromatic polymers with a controlled structure
发明人：GHELFI FRANCO; FERRANDO ANGELO; LONGO ALDO; BUFFAGNI MIRKO
权利人:VERSALIS SPA
摘要:The present invention relates to a polymerization process for the synthesis of vinyl aromatic polymers, in which the sequence of monomers in the chain and the linear, branched soluble, or crosslinked insoluble structure, with reactive or different polarity functions, are controlled. Said process comprises the step of polymerizing vinyl aromatic monomers by means of an Atom Transfer Radical Polymerization (ATRP) reaction with an Activator ReGenerated by Electron Transfer (ARGET), the reaction being carried out at a temperature comprised between 25° C. and 110° C. in an inert gas atmosphere in the presence of a complex catalyst containing a cupric halide and a multidentate amine ligand, feeding to the reaction an organic initiator having two geminal halogens, an alkali metal (bi)carbonate, a solvent pair of an aliphatic alcohol and an acetic ester of the same aliphatic alcohol and possibly ascorbic acid, provided that no initiator is used with three or more active halogens, or polyvinyl monomers or inimers.

专利号:US-6610802-B2
优先权日:2001-05-29
标题 :Process for synthesis of polymer compositions, polymer compositionS obtainable by the process, and use of the same
发明人：ROOS SEBASTIAN; EISENBERG BORIS; HARPE CAROLIN
权利人:ROHMAX ADDITIVES GMBH
摘要:The present invention relates to a process for synthesis of polymer compositions with reduced catalyst content, wherein ethylenically unsaturated monomers containing less than 0.5 wt % of ethylenically unsaturated monomers with at least one carboxylic group, sulfonic acid group and/or at least one phosphonic acid group relative to the total weight of the ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts and, after the polymerization, the catalyst contained in the polymer is at least partly separated. For this purpose, the polymer composition is filtered, after the polymerization, in the presence of at least one filter aid which contains at least 0.5 wt %, relative to the total weight of the filter aid, of repeating units that contain at least one carboxylic acid group, sulfonic acid group and/or at least one phosphonic acid group.

专利号:US-6610801-B1
优先权日:2000-11-13
标题:Processes for synthesis of polymer compositions
发明人：SCHERER MARKUS
权利人:ROHMAX ADDITIVES GMBH
摘要:The present invention relates to processes for synthesis of poly(meth)acrylate compositions, wherein ethylenically unsaturated monomers are transformed to polymers by means of initiators containing a transferable group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, wherein ethylenically unsaturated monomers containing 50 to 100 wt %, relative to the total weight of ethylenically unsaturated monomers, of (meth)acrylates of formula (I) are polymerizedwherein R denotes hydrogen or methyl, R1 denotes a straight-chain or branched alkyl group with 8 to 40, carbon atoms, R2 and R3 independently denote hydrogen or a group of the formula -COOR1, wherein R' denotes hydrogen or a straight-chain or branched alkyl group with 8 to 40, carbon atoms, in the presence of copper, the total concentration of copper of oxidation numbers (I) and (II) in the polymerization composition being <=200 ppm relative to the total weight of the composition.

专利号:US-6639029-B1
优先权日:2000-11-13
标 题 :Process for continuous synthesis of polymer compositions as well as use of same
发明人：SCHERER MARKUS; BOLLINGER JOSEPH MARTIN; COOPER JR DAVID J; TILLERY LARRY STEPHEN; WOODRUFF ROBERT
权利人:ROHMAX ADDITIVES GMBH
摘要:The present invention relates to a process for synthesis of polymer compositions, wherein ethylenically unsaturated monomers are polymerized by means of initiators containing a transferable atom or group of atoms and of one or more catalysts comprising at least one transition metal in the presence of ligands which can form a coordination compound with the metal catalyst or catalysts, the process being characterized in that the polymerization takes place by means of continuous process operation.