CAS: 19351-63-4; Secologanin

上下游产品

methanol O,O,O,O-tetraacetylsecologaninn loganin (E)-4-(2',3',4',6'-Tetra-O-acetyl-β-D-glucopyranosyloxy)but-3-en-2-onesecologanin tetraacetate strictosidine O-acetyl-β-D-glucopyranosyloxy)-16α-vinyl-(3ξ,15β)-18-oxa-yohimb-19-en-21-one17β-(tetra-O-acetyl-β-D-glucopyranosyloxy)-16α-vinyl-(3ξ,15β)-18-oxa-yohimb-19-en-21-one cathenamine

📜马钱子苷置于cell Suspension Of Lonicera Tatarica体系中,用 水 用作溶剂,化学反应生成开联番木鳖苷
参考文献:放射免疫法测定马钱素和通过植物细胞培养物将马钱素生物转化为赛洛加宁
标题:放射免疫法测定马钱素和通过植物细胞培养物将马钱素生物转化为赛洛加宁
摘要:摘要 已经开发了一种放射免疫分析技术,用于定量测量来自整株植物和培养植物细胞的新鲜和干燥材料的粗提取物中的马钱素.该测定利用 6'-羧基多糖苷,其通过与牛血清白蛋白连接而具有免疫原性.示踪分子是通过马钱素的葡萄糖部分的高碘酸盐打开和随后用高比活性的硼酸化钠还原来合成的.兔抗体对马钱素具有高亲和力 (K A = 1.6 x 10 9 1/mol),并且允许每 0.05 Ml 样品检测低至 0.1 Ng.该抗血清对马钱素及其苷元具有高度特异性,只有 10-羟基马钱素和 7-表皮马钱素表现出显着的交叉反应性.测试了许多忍冬科细胞培养物将添加的马钱素转化为赛洛加宁的能力.通过标记前体喂养实验,发现威格利亚属,忍冬属,绣球属和红花属的成员打开马钱素的环戊烷环.马钱素生物转化的时间过程使用马钱素和二甲双胍的放射免疫测定法以及作为生物材料的忍冬属植物细胞培养物进行监测.
Doi:10.1016/s0031-9422(00)84941-9

专利信息

专利号:US-2025092433-A1
优先权日:2023-09-20
标 题:Polypeptides for use in the synthesis of kratom alkaloids
发明人：CASARETTO JOSE; AKTAR TARIQ A; ROTHSTEIN STEVEN; SOUBEYRAND ERIC
权利人:MITRADYNE CORP
摘要:Described herein are polypeptides encoding enzymes for the synthesis of monoterpene indole alkaloids. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1-68, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1-68, or a fragment of the polypeptide, or the variant thereof.

专利号:EP-1548006-B1
优先权日:2003-12-12
标题 :Synthesis of tetraazapentamethine derivatives, keratin fibers dyeing process which uses such synthesis
发明人：PEREIRA RUI; BURGAUD HERVE
权利人:OREAL
摘要:Producing tetraazapentamethine compounds (I) comprising reacting an azine compound with an oxidizing agent, is new. Producing tetraazapentamethine compounds of formula (I) comprises reacting an azine compound of formula (VI) or (VII) with an oxidizing agent; [Image] [Image] W1a cationic heteroaromatic group of formula (II) or (III); W2a heteroaromatic group of formula (IV) or (V); Z14Z7 or Z1; Z15Z8 or Z2; Z16Z13 or Z0; R25R5 or R1; Z17Z9 or Z3; Z18Z10 or Z4; Z19Z11 or Z5; Z20Z12 or Z6; R26R8 or R3; R27R7 or R4; R28, R29H, 1-6C alkyl or 1-6C alkoxy, but not both H; Z0CR2, N or NR21; Z1O, S or NR9; Z2N or CR10; Z3N or CR11; Z4N or CR12; Z5N or CR13; Z5N or CR13; Z6N or CR14; Z7O, S or NR15; Z8N or CR16; Z9N or CR17; Z10N or CR18; Z11N or CR19; Z12N or CR20; Z13CR6, N or NR22; R2, R6, R10, R16H; 1-4C alkyl substituted with 0-3 of OH, 1-2C alkoxy, 2-4C (poly)hydroxyalkoxy, NH2, 1-2C (di)alkylamino, COOH or SO3H; phenyl substituted with 0-2 of OH, 1-2C alkoxy, 2-4C (poly)hydroxyalkoxy, NH2, 1-2C (di)alkylamino; COOH; sulfonylamino; R1, R4, R5, R7, R9, R15, R21, R221-6C alkyl substituted with 0-3 of OH, 1-2C alkoxy, 2-4C (poly)hydroxyalkoxy, NH2, 1-2C (di)alkylamino, COOH or SO3H; R0, R3, R8, R11-R14, R17-R20H; 1-6C linear or branched hydrocarbyl with 0-3 unsaturations, optionally substituted with 1-3 of OH, 1-2C alkoxy, 2-4C (poly)hydroxyalkoxy, NH2, 1-2C (di)alkylamino, COOH, SO3H, sulfonylamino, 2-4C (poly)hydroxyalkylamino or halo and optionally interrupted by O, N, S or SO2; phenyl optionally substituted with 1-3 of OH, 1-2C alkoxy, 2-4C (poly)hydroxyalkoxy, NH2, 1-2C (di)alkylamino, COOH, SO3H, sulfonylamino, 2-4C (poly)hydroxyalkylamino or halo; pyrazolyl, pyrrolyl, imidazolyl, thiazolyl, oxazolyl, triazolyl, pyridyl, pyrimidinyl, triazinyl, pyrazinyl or pyridazinyl; X : an anion; R2+R10, R11+R12, R6+R16, R17+R18 can form a 5-6C aromatic ring substituted with 0-2 of OH, NH2, 1-2C (di)alkylamino, 1-2C alkoxy, 2-4C (poly)hydroxyalkylamino. An independent claim is also included for dyeing keratinic fibers by applying (VI) or (VII) onto the wet or dry fibers in the presence of an oxidizing agent. [Image].

专利号:US-2025304985-A1
优先权日:2022-04-08
标题 :Genetically Engineered Plants for Increased Production of Vindoline
发明人：LEE-PARSONS CAROLYN; COLE LAUREN F
权利人:UNIV NORTHEASTERN
摘要:Two novel transcription factors, CrDELLA1 and CrDELLA2, are described in Catharanthus roseus plants. The DELLA transcription factors have a regulatory role in the synthesis of vinblastine and vincristine, two important anti-cancer compounds that have proved difficult to obtain in sufficient quantities. The present technology provides genetically modified C. roseus plants having enhanced DELLA activity, which leads to activation of multiple enzymes in the biosynthetic pathway leading to vinblastine and vincristine. The genetic modifications can be used together with activation of plant defense mechanisms and responses to light in order to boost vinblastine and vincristine synthesis.

专利号:US-7288120-B2
优先权日:2003-12-12
标题 :Synthesis of tetraazapentamethine compounds, and processes for dyeing keratin fibers using this synthesis
发明人：PEREIRA RUI; BURGAUD HERVE
权利人:OREAL
摘要:The present disclosure relates to processes for synthesizing tetraazapentamethine compounds that comprise reacting at least one compound of azine type with at least one oxidizing agent. The disclosure also relates to processes for dyeing keratin fibers, for example human keratin fibers, that comprise using such synthetic processes.

专利号:US-5843682-A
优先权日:1995-11-20
标题 :N-1-carboxyalkyl derivatives of LSD
发明人：SIGLER GERALD F; ROUHANI RIAZ; DAVOUDZAHEH DAVID
权利人:BOEHRINGER MANNHEIM CORP
摘要:Novel derivatives of LSD having the formula wherein R1 is an alkyl, cycloalkyl or aryl group having 1 to 10 carbon atoms, preferably an alkyl group having 1 carbon atom; R2 is a bond or wherein R3 is alkyl, cycloalkyl or aryl group having 2 to 10 carbon atoms, preferably an alkyl group having 2 or 5 carbon atoms; Z is an immunogenic carrier substance, an enzyme donor polypeptide or a label selected from the group consisting of an enzyme, a substance having fluorescent or luminescent properties and a radioactive substance; and n is 1 to p where p equals MW of Z/1000. The derivatives include maleimide conjugates of an immunogenic poly(amino acid), an enzyme donor polypeptide or a labeling substance such as an enzyme, a fluorescent substance or a radioactive substance. Novel activated hapten intermediates useful in the preparation of the conjugates and methods for synthesis of the hapten intermediates and their conjugate derivatives are also disclosed.

专利号:US-2005198744-A1
优先权日:2003-12-12
标 题:Synthesis of tetraazapentamethine compounds, and processes for dyeing keratin fibers using this synthesis