CAS: 10326-27-9; Barium Chloride Dihydrate

专利信息

专利号:US-12077484-B2
优先权日:2019-12-23
标 题 :Process for the synthesis of melphalan
发明人：ALLEGRINI PIETRO; BONETTI ANDREA; MOLINARI MARCO; GAMBINI ANDREA
权利人:INDENA SPA
摘要:The invention relates to a process for the preparation of Melphalan (4-[bis(2-chloroethyl)amino]-L-phenylalanine of formula (I)said process comprising the reaction of a 4-amino-L-phenylalanine protected at the carboxy and amino aminoacidic groups with an agent able to convert the aromatic amino group into a group of formula: —N(CH2CH2OS(O)nO−)2, wherein n is 1 or 2 followed by conversion of the —N(CH2CH2OS(O)nO−)2 group into a —N(CH2CH2Cl)2 group.The invention also provides novel intermediates useful for the preparation of Melphalan.

专利号:US-6319695-B1
优先权日:1991-10-15
标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
发明人：WONG CHI-HUEY; ICHIKAWA YOSHITAKA; SHEN GWO-JENN; LIU KUN-CHIN
权利人:SCRIPPS RES INSITUTE
摘要:This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein is the use of a disclosed method for fucosylation.

专利号:EP-3485971-A1
优先权日:2017-11-21
标 题:Catalyst and process for the synthesis of fatty acid esters
发明人：LAROCCA SUSANNA; CAVANI FABRIZIO; VELASQUEZ OCHOA JULIANA; MELLONI MATTIA
权利人:SO G I S IND CHIMICA S P A; UNIV BOLOGNA ALMA MATER STUDIORUM
摘要:The present invention relates to a heterogeneous catalyst comprising silica (SiO2) and a metal co-oxide selected from the group consisting of magnesium oxide (MgO), calcium oxide (CaO), barium oxide (BaO) and zinc oxide (ZnO) and having a metal co-oxide/SiO 2 molar ratio between 0.05 and 0.3. The invention also relates to a process for preparing esters of one or more fatty acids with one or more alcohols comprising the step of reacting the one or more fatty acids with the one or more alcohols in the presence of the heterogenous catalyst, and to a process for manufacturing the heterogeneous catalyst.

专利号:US-2023286901-A1
优先权日:2019-12-23
标题:Process for the synthesis of melphalan

专利号:US-7973109-B2
优先权日:2007-03-29
标 题 :Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution
发明人：OGATA SHIN-ICHI; FUKUSHIMA YOSHIAKI; KAWASUMI MASAYA
权利人:TOYOTA CHUO KENKYUSHO KK
摘要:A process for producing a crosslinked type or non-crosslinked type layered metal phosphonate compound including a reaction step of reacting two or more members selected from organic diphosphonic acids or monophosphonic acids, or derivatives thereof having predetermined conditions and a metal source capable of forming an ion of a hexacoordinate metal atom as a central atom (M) of a metal oxide octahedron upon reaction under the presence of a sulfuric acid catalyst, a crosslinked or non-crosslinked metal phosphonate compound obtained by the process, as well as a stock solution used for the synthesis of the crosslinked or non-crosslinked type layered metal phosphonate compound described above.

专利号:EP-4081503-B1
优先权日:2019-12-23
标题:A process for the synthesis of melphalan