CAS: 953075-90-6; (2,6-Diethyl-4-Methylphenyl)Boronic Acid

该化合物是一种黄酸衍生物,其特点是其气态阻塞的芳香环,这在铃木-宫浦交织等交叉反应中加强了选择性.乙基和甲基替代成分分别存在于2,6和4个位置上,这提高了稳定性并减少了血清含量,使它成为建造复合芳烃框架的可靠试剂.其富含电子芳香系统进一步促进了催化循环中的高效转解.该化合物在制药和农用化学合成中特别有用,在其中,精确控制双子体债券形成至关重要.在温反应条件下的高纯度和持续性能强调了其在先进有机合成中的实用性.

英文名称(2,6-Diethyl-4-Methylphenyl)Boronic Acid
中文名称(2,6-二乙基-4-甲基苯基)硼酸
IUPAC名称(2,6-diethyl-4-methylphenyl)boronic acid
其它别名2,6-Diethyl-4-Methylphenylboronic Acid; Boronic Acid, B-(2,6-Diethyl-4-Methylphenyl)-; B-(2,6-Diethyl-4-Methylphenyl)Boronic Acid
CAS编号953075-90-6
MFCD编号:MFCD25563305
分子式:C11H17BO2分子量:192.07
产品CID: 2006198
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: RJIQZLJNCMHCCN-UHFFFAOYSA-N
InChI=1S/C11H17BO2/c1-4-9-6-8(3)7-10(5-2)11(9)12(13)14/h6-7,13-14H,4-5H2,1-3H3
计算化学: 氢键受体数2.0氢键供体数2可旋转键数3

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

上下游产品

Trimethyl borate 1-bromo-2,6-diethyl-4-methylbenzene 2-(2,6-diethyl-4-methylphenyl)-3-methoxy-cyclopent-2-en-1-one 2-(2,6-diethyl-4-methylphenyl)-5-([1,3]dioxolan-2-ylmethyl)cyclohexane-1,3-dione (2,6-diethyl-4-methylphenyl)acetic acid ethyl ester 2-(2,6-diethyl-4-methylphenyl)-5-[2-(ethylsulfinyl)propyl]-cyclohexane-1,3-dione

合成工艺路线路线简述

合成目标产物 2,6-Diethyl-4-Methylphenylboronic Acid 主要起始原料 Trimethyl Borate And 2,6-Diethyl-4-Methylbromobenzene
314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 10 Min,-78 °C; 10 Min,-78 °C1.2 Reagents: Trimethyl Borate; 30 Min,-78 °C; 1 H,-78 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water
标题:Cyclohexanedione Derivatives As Novel Herbicides And Their Preparation
参考文献:World Intellectual Property Organization]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 85 Min,-70 °C; 30 Min,-70 °C1.2 15 Min,-70 °C; 1 H,-70 °C; 18 H,Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; 10 Min,Rt; 4 H,Rt
标题:Compositions Comprising Pyridazinone Derivative,Glyphosate Or Salt Thereof,And Specific Herbicide
参考文献:Japan]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 85 Min,-70 °C; 30 Min,-70 °C1.2 Reagents: Trimethyl Borate; 15 Min,-70 °C; 1 H,-70 °C; 18 H,Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; 10 Min,Rt; 4 H,Rt
标题:Compositions Comprising Pyridazinone Derivative,Glyphosate Or Salt Thereof,And Specific Herbicide
参考文献:World Intellectual Property Organization]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Tert-Butyllithium Solvents: Tetrahydrofuran,Hexane; 85 Min,-70 °C; 30 Min,-70 °C1.2 Reagents: Trimethyl Borate; 15 Min,-70 °C; 1 H,-70 °C; 18 H,Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; 10 Min,Rt; 4 H,Rt
标题:Compositions Comprising Pyridazinone Derivative,Specific Herbicide,And Specific Safener
参考文献:World Intellectual Property Organization]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 50 Min,-65 °C; 0.5 H,-65 °C1.2 Reagents: Trimethyl Borate; 45 Min,-65 °C; 0.5 H,-65 °C1.3 Reagents: Hydrochloric Acid Solvents: Water
标题:Preparation Of 2,6-Diethyl-4-Methylphenylacetate
参考文献:China]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 10 Min,-78 °C; 10 Min,-78 °C1.2 Reagents: Trimethyl Borate; 30 Min,-78 °C; 1 H,-78 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water
标题:2-Aryl-5-Heterocyclylcyclohexane-1,3-Dione Compounds And Their Use As Herbicides And Their Preparation
参考文献:World Intellectual Property Organization]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 85 Min,-70 °C; 30 Min,-70 °C1.2 Reagents: Trimethyl Borate; 15 Min,-70 °C; 1 H,-70 °C; 18 H,Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; 10 Min,Rt; 4 H,Rt
标题:Use Of Pyridazinone Compound For Control Of Harmful Arthropod Pests
参考文献:World Intellectual Property Organization]

314084-61-2 = 953075-90-6
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 85 Min,-70 °C; 30 Min,-70 °C1.2 Reagents: Trimethyl Borate; 15 Min,-70 °C; 1 H,-70 °C; 18 H,Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; 10 Min,Rt; 4 H,Rt
标题:Herbicidal Composition Contains The Pyridazinone Compound
参考文献:Japan]

= 953075-90-6 [标题:Reaction Conditions
标题:Pyridazinone Compound And Use Thereof As Herbicides
参考文献:United States]

= 953075-90-6 [标题:Reaction Conditions
标题:Preparation Of Pyridazinones As Herbicides.
参考文献:World Intellectual Property Organization]

314084-61-2 = 953075-90-6 + 2050-24-0
反应条件:1.1 Reagents: Ethylmagnesium Bromide,Magnesium Solvents: 2-Methyltetrahydrofuran; 65 °C; 1 H,65 °C; 65 °C -> 25 °C; 25 °C -> 5 °C1.2 Reagents: Trimethyl Borate Solvents: Toluene; 0 - 5 °C; 8 - 10 °C; 10 °C -> 25 °C; 90 Min,20 - 25 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; 15 Min,< 35 °C
标题:Development Of A Practical Process For The Large-Scale Preparation Of The Chiral Pyridyl-Backbone For The Crabtree/pfaltz-Type Iridium Complex Used In The Industrial Production Of The Novel Fungicide Inpyrfluxam
作者:Jones,Michelle; Harris,Dave; Struble,Justin; Hayes,Michael; Koeller,Kevin; Et Al
参考文献:Organic Process Research & Development 日期:2022 卷标:26(8) 页码:2407-2414