合成目标产物 Teflubenzuron 主要起始原料 2,6-Difluorobenzoyl Isocyanate And 2,4-Difluoro-3,5-Dichloroaniline
83121-15-7 + 60731-73-9 = 83121-18-0 反应条件:1.1 Solvents: 1,2-Dichloroethane; 5 - 6 H,Reflux 标题:Synthesis Of The Benzoylurea Insecticide Teflubenzuron 作者:Lu,Yang; Et Al 参考文献:Xiandai Nongyao 日期:2006 卷标:5(2) 页码:14-16]
= 83121-18-0 反应条件:1.1 Catalysts: Dimethyl Sulfoxide 标题:Preparation Of Benzoylurea Insecticides Such As Teflubenzuron By Oxidation Of Benzoylthioureas 参考文献:United Kingdom]
18063-03-1 + 83121-16-8 = 83121-18-0 反应条件:1.1 Solvents: Toluene; Rt -> Reflux; 7 - 8 H,Reflux 标题:Synthesis Of The Benzoylurea Insecticide Teflubenzuron 作者:Tu,Sai-Fei; Et Al 参考文献:Guangzhou Huagong 日期:2013 卷标:41(4) 页码:107-108]
83121-15-7 + 333-20-0 + 18063-02-0 = 83121-18-0 反应条件:1.1 -2.1 Catalysts: Dimethyl Sulfoxide 标题:Preparation Of Benzoylurea Insecticides Such As Teflubenzuron By Oxidation Of Benzoylthioureas 参考文献:United Kingdom]
18063-03-1 = 83121-18-0 反应条件:1.1 Solvents: Toluene; 30 Min,Rt; 3 - 4 H,Reflux2.1 Solvents: 1,2-Dichloroethane; Rt -> Reflux; 5 - 6 H,Reflux 标题:New Technique For Synthesis Of Benzoylurea Insecticide Teflubenzuron 作者:Lu,Yang; Et Al 参考文献:Yingyong Huagong 日期:2006 卷标:35(1) 页码:54-56]
18063-03-1 = 83121-18-0 [标题:Reaction Conditions 标题:Urea Derivatives And Their Use 参考文献:European Patent Organization]
385-00-2 = 83121-18-0 反应条件:1.1 Reagents: Thionyl Chloride2.1 -3.1 Catalysts: Dimethyl Sulfoxide 标题:Preparation Of Benzoylurea Insecticides Such As Teflubenzuron By Oxidation Of Benzoylthioureas 参考文献:United Kingdom]
专利号:WO-2025056767-A1 优先权日:2023-09-15 标题 :Process for the preparation of enantiomerically enriched aliphatic amines 发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS 权利人:SYNGENTA CROP PROTECTION AG 摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.
专利号:WO-2011067757-A1 优先权日:2009-12-06 标题 :INSECTICIDAL COMPOSITIONS OF CHITIN SYNTHESIS INHIBITORS (CSIs) AND THE ENTOMOPATHOGENIC FUNGUS NOMURAEA RILEYI 发明人:APPLEBAUM SHALOM W; ICHELCZIK DANA; BARAZANI AVNER 权利人:MAKHTESHIM CHEM WORKS LTD; YISSUM RES DEV CO; APPLEBAUM SHALOM W; ICHELCZIK DANA; BARAZANI AVNER 摘要:The present invention discloses a pesticidal composition comprising a combination of a chitin synthesis inhibitor (CSI) and the fungus Nomuraea rileyi, wherein this composition is insecticidally effective and contains an insecticidally effective amount of a chitin synthesis inhibitor and an insecticidally effective amount of the fungus Nomuraea rileyi. Also are disclosed a method of treating or preventing pest infestation in a plant or in an environment in which this plant is grown, by contacting the plant or environment with the pesticidal composition of the invention, and a method for reducing the amount of CSI required to control insects, and the use of the pesticidal composition of the invention in controlling insects in a plant or an environment of the plant.
专利号:US-10906880-B2 优先权日:2016-01-26 标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application 发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI 权利人:UNIV NANKAI 摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.
专利号:US-7628979-B1 优先权日:2005-04-20 标题 :Use of calco oil blue V in bait formulations for marking and controlling subterranean termites 发明人:MORALES-RAMOS JUAN A; ROJAS MARIA G 权利人:US AGRICULTURE 摘要:Termite bait matrix containing cellulose, calco oil blue V (solvent blue 58 or 9,10-anthracenedione, 1,4-bis[(2-ethylhexyl)amino]), and optionally a termite toxicant (e.g., chitin synthesis inhibitor). Methods of monitoring termite activity in a region involving placing a termite bait matrix in the region and assessing the presence of termites at the site of the termite matrix, the termite bait matrix contains cellulose and 9,10-anthracenedione, 1,4-bis[(2-ethylhexyl)amino]. Methods of killing termites, involving placing a termite bait matrix in a termite habitat and allowing termites to feed on the bait matrix, the termite bait matrix contains cellulose, 9,10-anthracenedione, 1,4-bis[(2-ethylhexyl)amino], and a termite toxicant (e.g., chitin synthesis inhibitor).
专利号:WO-02087337-A3 优先权日:2001-05-01 标 题:Pesticidal compositions comprising a chitin synthesis inhibitor and piperonyl butoxide 发明人:VERBRUGGEN LUC ROSALIA MICHAEL 权利人:JANSSEN PHARMACEUTICA NV; VERBRUGGEN LUC ROSALIA MICHAEL 摘要:The present invention relates to pesticide compositions and particularly to compositions which are able to provide an improved protecting effect against invertebrates such as insects and acari. More particularly, the present invention relates to synergistic pesticide compositions comprising a chitin synthesis inhibitor and piperonyl butoxide for protecting any living or non-living material, such as crops, plants, fruits, seeds, building parts made of wood, thatch or the like, biodegradable material and textiles against deterioration due to the action of pests such as insects and for treating animals, especially mammals, gallinaceae and anatidae, against such harmful invertebrates. This invention thus relates to the field of protection of plants, crops, warm-blooded animals, food, building materials and textiles through the control of pests. The chitin biosynthesis inhibitors are specifically, bistrifluron, buprofezin, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, teflubenzuron or triflumuron. Preferred is flufenoxuron.
专利号:EP-1306084-B1 优先权日:1998-06-09 标 题 :Compositions for the control of parasitic infestations in fish 发明人:ALEXANDER SVEIN; EVENSEN OYSTEIN; SYVERTSEN CHRISTIAN; MARTINSEN BERNT 权利人:PHARMAQ AS 摘要:Injectable compositions comprising antiparasitically active chitin synthesis inhibitor substances are described, for controlling parasitic infestations including infestations with sea lice and isopod species in farmed fish. The compositions are optionally formulated in a fish vaccine. The antiparasitically active chitin synthesis inhibitor substances protect the fish against parasites for a substantial period of time after injection. Useful embodiments include compositions with lufenuron that confer protection against new parasitic infestation for an extended period of time after treatment.
1: Reshuffling of Aspergillus fumigatus Cell Wall Components Chitin and β-Glucan under the Influence of Caspofungin or Nikkomycin Z Alone or in Combination Patricia E. B. Verwer, M. L. van Duijn, M. Tavakol, Irma A. J. M. Bakker-Woudenberg, Wendy W. J. van de Sande Antimicrob Agents Chemother. 2012 Mar; 56(3): 1595–1598. doi: 10.1128/AAC.05323-11 An overview and outlook with emphasis on efficacy, usage and resistance Pablo Junquera, Barry Hosking, Marta Gameiro, Alicia Macdonald Parasite. 2019; 26: 26. Published online 2019 May 1. doi: 10.1051/parasite/2019026 2019; 14(9): e0222520. Published online 2019 Sep 23. doi: 10.1371/journal.pone.0222520 Toé, Laurence Gamet-Payrastre, Pierre I. Guissou Toxicol Rep. 2014; 1: 474–489. Published online 2014 Jul 25. doi: 10.1016/j.toxrep.2014.07.008 Poley, Laura M. Braden, Amber M. Messmer, Okechukwu O. Igboeli, Shona K. Whyte, Alicia Macdonald, Jose Rodriguez, Marta Gameiro, Lucien Rufener, Jacques Bouvier, Dorota W. Wadowska, Ben F. Koop, Barry C. Hosking, Mark D. Fast Int J Parasitol Drugs Drug Resist. 2018 Aug; 8(2): 174–188. Published online 2018 Mar 13. doi: 10.1016/j.ijpddr.2018.02.007 2013 Mar; 36(3): 171–194. Published online 2013 Jan 13. doi: 10.1111/jfd.12061 Meagher, Jr., Neil Miller, Lambert Kanga, Muhammad Haseeb, José Eduardo Serrão, Carlos Frederico Wilcken, José Cola Zanuncio PLoS One. 2018; 13(11): e0206789. Published online 2018 Nov 8. doi: 10.1371/journal.pone.0206789 2015;
合成参考文献
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