📜3-硝基-4-吡啶乙酸乙酯置于盐酸,Palladium 10% On Activated Carbon,氢气,二异丁基氢化铝,三乙胺体系中,用 四氢呋喃,乙醇,二氯甲烷,水 作为反应溶剂,20.0 °C,300.01 Kpa 条件下,反应 68.0H,反应生成 2,3-二氢-1H-吡咯并[2,3-C]吡啶 参考文献:Preparation Of Azaindolines And Benzoyl Substituted Azaindolines: Precursors Of Triazabenzo[cd]Azulen-9-One Pde4 Inhibitors 标题:Preparation Of Azaindolines And Benzoyl Substituted Azaindolines: Precursors Of Triazabenzo[cd]Azulen-9-One Pde4 Inhibitors 摘要:The Syntheses Of Various Substituted Azaindolines Are Described. Azaindolines Were Identified As Potential Key Intermediates Towards New Pde4 Inhibitors. (C) 2011 Elsevier Ltd. All Rights Reserved. DOI:10.1016/j.Tetlet.2011.08.009
专利号:US-2004146539-A1 优先权日:2003-01-24 标 题:Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits 发明人:GUPTA SHYAM K 摘要:I have discovered cosmetic or topical pharmaceutical compositions for external body part or organ slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that are in synergistic combination with benefits for the treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, spider veins reduction, blood microcirculation (venous insufficiency) improvement, UVA/UVB protection of skin, and skin redness reduction. These compositions thus provide multiple combinations of skin and external body part or organ enhancement benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, “love handlesâ€? in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a body beneficial composition selected from certain nutraceutical, cosmetic, and pharmaceutical ingredients, a composition to promote collagen and elastin synthesis in the skin, and a cosmetically or pharmaceutically acceptable delivery ystem.
专利号:WO-2024178332-A1 优先权日:2023-02-24 标题 :Compounds 发明人:COROPCEANU IGOR; IPPEN CHRISTIAN JUSTUS; BARRON ALAIN CHRISTOPHER 权利人:SHOEI CHEMICAL IND CO 摘要:Disclosed are examples of chemical compounds useful as ligands for photoluminescent particles, such as nanoparticles, populations of the particles comprising such ligands, films and other compositions comprising the ligated particles, and methods of synthesis.
专利号:US-8415400-B2 优先权日:2003-05-16 标题:Cross-linked ionic core micelles 发明人:BRONICH TATIANA K; KABANOV ALEXANDER V 权利人:BRONICH TATIANA K; KABANOV ALEXANDER V; UNIV NEBRASKA 摘要:The present invention provides polymer micelles with cross-linked ionic cores as delivery vehicles for therapeutics, diagnostics, nucleic acids, proteins, small molecules and the like. The present invention provides additionally methods of synthesis and uses for such micelles.