CAS: 760919-39-9; 2,3-Dihydro-1H-Pyrrolo[2,3-C]Pyridine

该化合物是结合的热循环化合物,其特点是以部分饱和的丙烯菊酯形态凝结的火花环,具有独特的电子和消毒特性,使其成为制药和农用化学合成中有价值的中间体,其部分饱和性框架增强了稳定性,同时保持了进一步功能化的再现性,如通奸或交叉反应.该化合物的僵硬双环系统对设计生物活性分子很有优势,特别是在CNS瞄准药物或动脉抑制剂中.其多功能性作为胶囊可以精确地调节物理化学特性,改进溶性或将药物发现应用中的亲近性结合性.该产品通常以高纯度供应,确保研发工作流程的再生性.

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1610028-39-1 1196155-89-1 1432681-13-4

合成工艺路线路线简述

    📜3-硝基-4-吡啶乙酸乙酯置于盐酸,Palladium 10% On Activated Carbon,氢气,二异丁基氢化铝,三乙胺体系中,用 四氢呋喃,乙醇,二氯甲烷,水 作为反应溶剂,20.0 °C,300.01 Kpa 条件下,反应 68.0H,反应生成 2,3-二氢-1H-吡咯并[2,3-C]吡啶
    参考文献:Preparation Of Azaindolines And Benzoyl Substituted Azaindolines: Precursors Of Triazabenzo[cd]Azulen-9-One Pde4 Inhibitors
    标题:Preparation Of Azaindolines And Benzoyl Substituted Azaindolines: Precursors Of Triazabenzo[cd]Azulen-9-One Pde4 Inhibitors
    摘要:The Syntheses Of Various Substituted Azaindolines Are Described. Azaindolines Were Identified As Potential Key Intermediates Towards New Pde4 Inhibitors. (C) 2011 Elsevier Ltd. All Rights Reserved.
    DOI:10.1016/j.Tetlet.2011.08.009

    海关参考信息

    专利信息


    专利号:US-2004146539-A1
    优先权日:2003-01-24
    标 题:Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
    发明人:GUPTA SHYAM K
    摘要:I have discovered cosmetic or topical pharmaceutical compositions for external body part or organ slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that are in synergistic combination with benefits for the treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, spider veins reduction, blood microcirculation (venous insufficiency) improvement, UVA/UVB protection of skin, and skin redness reduction. These compositions thus provide multiple combinations of skin and external body part or organ enhancement benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, “love handlesâ€? in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a body beneficial composition selected from certain nutraceutical, cosmetic, and pharmaceutical ingredients, a composition to promote collagen and elastin synthesis in the skin, and a cosmetically or pharmaceutically acceptable delivery ystem.

    专利号:WO-2024178332-A1
    优先权日:2023-02-24
    标题 :Compounds
    发明人:COROPCEANU IGOR; IPPEN CHRISTIAN JUSTUS; BARRON ALAIN CHRISTOPHER
    权利人:SHOEI CHEMICAL IND CO
    摘要:Disclosed are examples of chemical compounds useful as ligands for photoluminescent particles, such as nanoparticles, populations of the particles comprising such ligands, films and other compositions comprising the ligated particles, and methods of synthesis.

    专利号:US-8415400-B2
    优先权日:2003-05-16
    标题:Cross-linked ionic core micelles
    发明人:BRONICH TATIANA K; KABANOV ALEXANDER V
    权利人:BRONICH TATIANA K; KABANOV ALEXANDER V; UNIV NEBRASKA
    摘要:The present invention provides polymer micelles with cross-linked ionic cores as delivery vehicles for therapeutics, diagnostics, nucleic acids, proteins, small molecules and the like. The present invention provides additionally methods of synthesis and uses for such micelles.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s11030-023-10641-7
    摘要:Neo AG, Ramiro JL, García-Valverde M, Díaz J, Marcos CF. Stefano Marcaccini: a pioneer in isocyanide chemistry. Mol Divers. 2023 Apr 12;28(1):335–418. doi: 10.1007/s11030-023-10641-7.
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