CAS: 719-59-5; (2-Amino-5-Chlorophenyl)(Phenyl)Methanone

上下游产品

CAS号1159372-20-9 rac-(2-amino-5-... | CAS号719-64-2 5-氯-3-苯基苯并[c]异唑 | CAS号106-47-8 对氯苯胺 | CAS号100-47-0 苯甲腈 | CAS号86230-82-2 7-chloro-9-phen... | CAS号98-88-4 苯甲酰氯 | CAS号5922-60-1 2-氨基-5-氯苯腈 | CAS号100-58-3 苯基溴化镁 | CAS号78823-09-3 2'-Benzoyl-4'-c... | CAS号1022-13-5 2-甲基氨-5-氯二苯甲酮 | CAS号10456-86-7 ethyl 2-(2-benz... | CAS号111044-20-3 2-(2-benzoyl-4-... | CAS号5958-24-7 6-氯-2-(氯甲基)-4-苯... | CAS号32580-26-0 2-(2-溴乙酰氨基)-5-氯二苯甲酮 | CAS号4016-85-7 2'-苯甲酰-2,4'-二氯乙酰苯胺 | CAS号21923-43-3 2-(4-bromopheny... | CAS号22609-01-4 6-Chloro-3-etho... | CAS号22609-02-5 6-氯-3-乙酰基-2-甲基-... | CAS号19144-20-8 ethyl 2-(2-benz... | CAS号22609-12-7 6-chloro-2-meth...

麦达西泮置于盐酸体系中,化学反应生成 2-氨基-5-氯二苯甲酮
参考文献:Schutz; Fitz,Arzneimittel-Forschung/drug Research,1982,Vol. 32,# 3,P. 177-183
标题:Schutz; Fitz,Arzneimittel-Forschung/drug Research,1982,Vol. 32,# 3,P. 177-183

专利信息

专利号:EP-3792250-A1
优先权日:2019-09-13
标题:Synthesis of alpha-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-3763171-A
优先权日:1969-02-26
标 题:Preparation of intermediates for the preparation of 1,3 - dihydro - 2h-1,4-benzodiazepin-1-ones
发明人：MC CAULLY R
权利人:AMERICAN HOME PROD
摘要:TWO ROUTES FOR THE PREPARATION OF 2-(2-ACYLAMINDO-2AMINO)-ACETAMIDOPHENYL ARYL KETONES, USED AS INTERMEDIATES IN THE SYNTHESIS OF PSYCHOLEPTIC 1,3-DIHYDRO-2H1,4-BENZODIAZEPIN-2-ONES ARE DESCRIBED. THE FIRST OF THESE ROUTES INVOLVES THE FORMATION OF A 2-N2,2-DIACYLOXY) ACETAMIDOPHENYL ARYL KETONE FROM GLYOXYLIC ACID AND AN ARYL PHENYL KETONE VIA EITHER A 2,2-DIACYLOXY ACETYL HALIDE OR A 2,2-DIACYLOXY ACETYL ANHYDRIDE, CONVERSION THEREOF TO THE CORRESPONDING 2-(2-ACYLAMIDO-2-HYDROXY)ACETAMIDOPHENYL ARYL KETONE DIRECTLY OR VIA THE 2-(2,2-DIHYDROXY) ACETAMIDOPHENYL ARYL KETONE, FORMATION OF THE CORRSPONDING 2-(2-ACYLAMIDO-2-HALO) ACETAMIDOPHENYL ARYL KETONE, AND CONVERSION TO THE 2-(2-ACYLAMIDO-2-AMINO) ACETAMIDOPHENYL ARYL KETONE. THE SECOND ROUTE FORMS THE 2-(2,2-DIHYDROXY) ACETAMIDOPHENYL ARYL KETONE BY REACTING A 2,3-DICARBOXYLICACYL TARTARIC ANHYDRIDE WITH A 2-AMINOPHENYL ARYL KETONE TO OBTAIN A 2-(3-CARBOXY-2,3ACYLOXY) PROPIONAMIDOPHENYL ARYL KETONE, SELECTIVELY HYDROLYZING THE SO-OBTAINED KETONE AND SELECTIVELY OXIDIZING THE PRODUCT WITH A VIX GLYCOL CLEAVING AGENT.

专利号:US-3896170-A
优先权日:1969-02-26
标题 :Intermediates for the preparation of 1,3-dihydro-2h-1, -benzodiazepin-2-ones
发明人：MCCAULLY RONALD J
权利人:AMERICAN HOME PROD
摘要:Two routes for the preparation of 2-(2-acylamido-2-amino)acetamidophenyl aryl ketones, used as intermediates in the synthesis of psycholeptic 1,3-dihydro-2H-1,4-benzodiazepin-2-ones are described. The first of these routes involves the formation of a 2-(2,2-diacyloxy)acetamidophenyl aryl ketone from glyoxylic acid and an aryl phenyl ketone via either a 2,2-diacyloxy acetyl halide or a 2,2-diacyloxy acetyl anhydride, conversion thereof to the corresponding 2-(2-acylamido-2-hydroxy) acetamidophenyl aryl ketone directly or via the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone, formation of the corresponding 2-(2-acylamido-2halo)acetamidophenyl aryl ketone, and conversion to the 2-(2acylamido-2-amino)acetamidophenyl aryl ketone. The second route forms the 2-(2,2-dihydroxy) acetamidophenyl aryl ketone by reacting a 2,3-dicarboxylicacyl tartaric anhydride with a 2aminophenyl aryl ketone to obtain a 2-(3-carboxy-2,3acyloxy)propionamidophenyl aryl ketone, selectively hydrolyzing the so-obtained ketone and selectively oxidizing the product with a vic glycol cleaving agent.

专利号:US-3883591-A
优先权日:1969-02-26
标 题:Intermediates for the preparation of 1,3-dihydro-2H-1,4-benzodiazepin-2-ones
发明人：MCCAULLY RONALD J
权利人:AMERICAN HOME PROD
摘要:Two routes for the preparation of 2-(2-acylamido-2-amino)acetamidophenyl aryl ketones, used as intermediates in the synthesis of psycholeptic 1,3-dihydro-2H-1,4-benzodiazepin-2-ones are described. The first of these routes involves the formation of a 2-(2,2-diacyloxy)acetamidophenyl aryl ketone from glyoxylic acid and an aryl phenyl ketone via either a 2,2-diacyloxy acetyl halide or a 2,2-diacyloxy acetyl anhydride, coversion thereof to the corresponding 2-(2-acylamido-2-hydroxy) acetamidophenyl aryl ketone directly or via the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone, formation of the corresponding 2-(2-acylamido-2halo)acetamidophenyl aryl ketone, and conversion to the 2-(2acylamido-2-amino)acetamidophenyl aryl ketone. The second route forms the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone by reacting a 2,3-dicarboxylicacyl tartaric anhydride with a 2aminophenyl aryl ketone to obtain a 2-(3-carboxy-2,3acyloxy)propionamidophenyl aryl ketone, selectively hydrolyzing the so-obtained ketone and selectively oxidizing the product with a vic glycol cleaving agent.

专利号:US-3899527-A
优先权日:1969-02-26
标题:Intermediates for the preparation of 1,3-dihydro-2H-1,4-benzodiazepin-2-ones
发明人：MCCAULLY RONALD J
权利人:AMERICAN HOME PROD
摘要:Two routes for the preparation of 2-(2-acylamido-2-amino)acetamidophenyl aryl ketones, used as intermediates in the synthesis of psycholeptic 1,3-dihydro-2H-1,4-benzodiazepin-2-ones are described. The first of these routes involves the formation of a 2-(2,2-diacyloxy)acetamidophenyl aryl ketone from glyoxylic acid and an aryl phenyl ketone via either a 2,2-diacyloxy acetyl halide or a 2,2-diacyloxy acetyl anhydride, conversion thereof to the corresponding 2-(2-acylamido-2-hydroxy) acetamidophenyl aryl ketone directly or via the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone, formation of the corresponding 2-(2-acylamido-2halo)acetamidophenyl aryl ketone, and conversion to the 2-(2acylamido-2-amino)acetamidophenyl aryl ketone. The second route forms the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone by reacting a 2,3-dicarboxylicacyl tartaric anhydride with a 2aminophenyl aryl ketone to obtain a 2-(3-carboxy-2,3acyloxy)propionamidophenyl aryl ketone, selectively hydrolyzing the so-obtained ketone and selectively oxidizing the product with a vic glycol cleaving agent.

专利号:US-2005042149-A1
优先权日:1994-04-01
标 题 :Nanoscale chemical synthesis
发明人：BARD ALLEN J
权利人:INTEGRATED CHEMICAL SYNTHESIZE
摘要:A modular reactor system and method for synthesizing nanoscale quantities of chemical compounds characterized by a continuous flow reactor under high pressure having uniform temperature throughout the reaction mixture. The apparatus includes a number of generic components such as pumps, flow channels, manifolds, flow restrictors, valves and at least one modular reactor, as small as one nanoliter in volume, where larger quantities can be produced by either using larger nanoscale sized units or adding parallel and serially disposed nanoscale reactor units.