CAS: 65185-58-2; 2-Bromophenethylamine

上下游产品

CAS号19472-74-3 邻溴氰苄 | CAS号65185-68-4 1-bromo-2-[(E)-... | CAS号6630-33-7 2-溴苯甲醛 | CAS号1074-15-3 1-溴-2-(2-溴乙基)苯 | CAS号75767-95-2 1H-Isoindole-1,... | CAS号496-15-1 二氢吲哚 | CAS号144631-04-9 N-[2-(2-bromoph... | CAS号2410-47-1 2-(2-bromopheny... | CAS号2861-59-8 1-甲酸基吲哚啉 | CAS号55268-74-1 吡喹酮 | CAS号61589-14-8 (2,3-二氢-1H-吲哚-1... | CAS号16078-30-1 N-已酰基吲哚啉 | CAS号1196-38-9 3,4-二氢异喹啉-1(2H)-酮 | CAS号171663-06-2 2-溴苯乙基氨基甲酸叔丁酯 | CAS号22990-19-8 1-苯基-1,2,3,4-四氢异喹啉

邻溴氰苄置于lithium Aluminium Tetrahydride,三氯化铝体系中,用 乙醚 作为反应溶剂,化学反应 18.0H,以90%的收率获得产物邻溴苯乙胺
参考文献:分子内钯催化的芳基胺化和芳基酰胺化
标题:分子内钯催化的芳基胺化和芳基酰胺化
摘要:在用钯催化剂和合适的碱处理后,芳族卤化物进行分子内取代以形成五元,六元和七元环.以类似的方式,将具有侧基酰胺或磺酰胺的芳基卤化物环化以形成五元和六元环.
DOI:10.1016/0040-4020(96)00266-9

专利信息

专利号:US-7078567-B2
优先权日:2001-03-07
标题:Amination process
发明人：JOHNSTON JEFFREY N; VISWANATHAN RAJESH
权利人:JOHNSTON JEFFREY N; VISWANATHAN RAJESH
摘要:The present invention provides methodology for carbon-nitrogen bond formation via vinyl or aryl amination. In the process of the invention, an sp 2 hybridized radical is reacted with an azomethine moiety to form pyrrolidine and indole compounds. The methodology provides a facile process for the synthesis of compounds having the pyrrolidine or indole subunit and is especially advantageous for compounds having acid or base labile functional groups and/or is comprised of chiral centers susceptible to acid/base epimerization.