CAS: 3571-88-8; (2E)-2-[(2E,4E)-3,5-Bis(3-Heptyl-4-Methyl-1,3-Thiazol-3-Ium-2-yl)Penta-2,4-Dienylidene]-3-Heptyl-4-Methyl-1,3-Thiazole,Diiodide
该化合物是一种复杂的有机化合物,其特征是其硫化物核心,即五人组成的含有硫磺和氮的热循环环.这种化合物具有双硫化物结构,表明存在两个由丙烯链连接的硫化物单位.七基和甲基替代元素有助于其防水特性,使其在各种应用中,包括有机电子和染色,具有潜在用途.碘化成分表明它可能表现出离子特性,影响其溶解剂的溶解性和再活性.此外,多种功能组的存在表明多种化学反应的潜力,可在合成化学化学中加以利用.
- 英文名称(2E)-2-[(2E,4E)-3,5-Bis(3-Heptyl-4-Methyl-1,3-Thiazol-3-Ium-2-yl)Penta-2,4-Dienylidene]-3-Heptyl-4-Methyl-1,3-Thiazole,Diiodide
- 中文名称普拉通宁
- IUPAC名称2,2'-(3-((3-Heptyl-4-methyl-2(3H)-thiazolylidene)ethylidene)-1-propene-1,3-diyl)bis(3-heptyl-4-methylthiazolium)diiodide
- 其它别名2,2'-[3-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)ethylidene]propenylene]bis[3-heptyl-4-methylthiazolium] diiodide; PLATONIN; platonin J; 2-[5-(2,3-Dihydro-3-heptyl-4-methylthiazole-2-ylidene)-3-[(3-heptyl-4-methylthiazole-3-ium)-2-yl]-1,3-pentadiene-1-yl]-3-heptyl-4-methylthiazole-3-ium・diiodide; NK 19; NK-19; Platonin iodide
- CAS编号3571-88-8
- MFCD编号:MFCD01680758
- EINECS号:222-681-5
- FDA UNII编号:0X9JDS6MF1
- 分子式:C38H61I2N3S3分子量:909.91498
- 产品CID: 1365764
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2901241000-1,3-丁二烯
2921199090-其他无环单胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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主要参考文献
1: Yeh CT, Kao MC, Chen CH, Huang CJ. Platonin preserves blood-brain barrier integrity in septic rats. Acta Anaesthesiol Taiwan. 2015 Mar;53(1):12-5. doi: 10.1016/j.aat.2015.02.001. Epub 2015 Mar 17. doi: 10.1016/j.jss.2017.08.054. Epub 2017 Sep 26. doi: 10.1038/srep42277.
4: Lee JJ, Chang CF, Sheu JR, Jayakumar T. Pharmacology and Clinical Effect of Platonin, a Cyanine Photosensitizing Dye: Potential Molecular Targets. Curr Pharm Biotechnol. 2014;15(8):700-11. doi: 10.1038/aps.2011.105. Epub 2011 Sep 5.
6: Hsu KY, Chen CH, Shih PC, Huang CJ. Adverse effects of bilateral lower limb ischemia-reperfusion on inducing kidney injuries in rats could be ameliorated by platonin. Acta Anaesthesiol Taiwan. 2012 Jun;50(2):63-8. doi: 10.1016/j.aat.2012.05.010. Epub 2012 Jun 26. Erratum in: Acta Anaesthesiol Scand. 2007 Feb;51(2):269. doi: 10.1007/s00011-008-8053-2. pii: E1100. doi: 10.3390/ijms19041100.
合成参考文献
参考文献:10.1038/srep42277
摘要:Sheu JR, Chen ZC, Jayakumar T, Chou DS, Yen TL, Lee HN, Pan SH, Hsia CH, Yang CH, Hsieh CY. A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice. Sci Rep. 2017 Feb 06;7():42277.
参考文献:10.1097/01.shk.0000184284.49752.38
摘要:Lee JJ, Lin MT, Wang NL, Lin CL, Chang CK. Platonin, a cyanine photosensitizing dye, causes attenuation of circulatory shock, hypercoagulable state, and tissue ischemia during heat stroke. Shock. 2005 Dec;24(6):577–82. doi: 10.1097/01.shk.0000184284.49752.38.
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