CAS: 2396-65-8; 1,8-Nonadiyne

该化合物是分子式C9H14的线性烷,其特点是在链中第一和第八碳原子上存在两三重保证,该化合物是多环体大家庭的一部分,因其多环体结层而具有独特的特性,有助于其反应和在有机合成和材料科学中的潜在应用. 1.8-Nonadiyne一般是一种无色液体,在室温下,其沸点相对类似分子重量的饱和碳氢化合物较低.其结构允许与其他分子进行有趣的互动,使其成为各种化学反应,包括聚合和协调化学反应的研究对象.此外,由于存在多种不饱和结合体,1,8-Nondidy可以参与各种附加反应,这些反应可在合成有机化学中加以利用.在处理该化合物时,应采取安全防范措施,因为如果吸入或摄取,它可能是易燃的,而且可能有害.

结构式图片

相似化合物

1720-38-3 764-93-2 765-10-6

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号111-24-0 1,5-二溴戊烷 | CAS号74-86-2 乙炔 | CAS号1066-26-8 乙炔化钠,二甲苯溶液 | CAS号7664-41-7 氨 | CAS号4900-30-5 1,8-壬二烯 | CAS号184846-57-9 11-benzylidenec... | CAS号24829-11-6 2,2'-(1,5-Penta... | CAS号30502-73-9 nonane-2,8-dione | CAS号1540-80-3 1,8-环十四二炔 | CAS号6237-59-8 苯六甲酸六甲酯 | CAS号1141757-09-6 tetramethyl 5-(... | CAS号1785-53-1 2,9-十一二炔 | CAS号7092-91-3 7,8,9,10-tetrah... | CAS号66031-49-0 non-1-en-8-yne

合成工艺路线路线简述

    📜1,5-二溴戊烷,乙炔钠置于氨体系中,化学反应生成1,8-壬二炔
    参考文献:Lespieau; Journaud,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1929,Vol. 188,P. 1410
    标题:Lespieau; Journaud,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1929,Vol. 188,P. 1410

    海关参考信息

    专利信息


    专利号:US-7109377-B2
    优先权日:1996-10-16
    标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
    发明人:SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
    权利人:HARVARD COLLEGE
    摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

    专利号:US-9006345-B2
    优先权日:2011-03-25
    标题 :Heterotrifunctional molecules and methods for the synthesis of dendrimeric materials
    发明人:LANCASTER JEFFREY; KOBERSTEIN JEFFREY T; TURRO NICHOLAS J
    权利人:LANCASTER JEFFREY; KOBERSTEIN JEFFREY T; TURRO NICHOLAS J; UNIV COLUMBIA
    摘要:In one aspect, the present invention is directed to dendrimers comprised of macromolecules and trifunctional branches. In another aspect, the invention relates to methods for generating dendrimeric compositions comprising macromolecules and trifunctional branches. In certain embodiments, the radial density of the dendrimeric composition is controlled by selective incorporation of branches.

    专利号:US-3578724-A
    优先权日:1968-03-04
    标 题:Migration and isomerization of acetylenes
    发明人:HUBERT ANDRE JULES
    权利人:UNION CARBIDE CORP
    摘要:PROCESS FOR THE MIGRATION OF ACETYLENIC BONDS AND A PROCESS FOR THE ISOMERIZATION OF HYDROCARBONS CONTAINING ACETYLENIC BONDS TO HYDROCARBONS CONTAINING CONJUGATED UNSATURATION, BY CONTACTING A COMPOUND CONTAINING ONE OR TWO ACETYLENIC BONDS WITH POTASSIUM AMIDE ON ALUMINA. THE UNSATURATED COMPOUNDS PRODUCED BY THE PROCESS OF THE INVENTION ARE USEFUL AS ULTRAVIOLET LIGHT ABSORBERS, AS CROSS-LINKING AGENTS FOR POLYOLEFINIC ELASTOMERS, AND AS INTERMEDIATES IN THE SYNTHESIS OF NEW COMPOUNDS.

    专利号:US-2003082830-A1
    优先权日:1996-10-16
    标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

    专利号:US-5977394-A
    优先权日:1998-03-13
    标题:Silyl thioalkene compound and method for the preparation thereof
    发明人:HAN LI-BIAO; TANAKA MASATO
    权利人:AGENCY IND SCIENCE TECHN
    摘要:Disclosed is a silyl thioalkene compound, as a class of organosilicon compounds, represented by the general formula n n R(--CSArâ•?CHSiX.sub.3).sub.n, n n in which the subscript n is 1 or 2, R is, when n is 1, a hydrogen atom or unsubstituted or substituted monovalent hydrocarbon group or, when n is 2, a divalent hydrocarbon group, Ar is an unsubstituted or nucleus-substituted aromatic monovalent aromatic hydrocarbon group and X is a halogen atom, a monovalent hydrocarbon group or hydrocarbyloxy group, having usefulness as an intermediate in the synthesis of various precision organic chemicals. The compound, of which X is a halogen atom X 1 , can be prepared, for example, by the reaction of an alkyne compound of the general formula n n R(--C.tbd.CH).sub.n, n n with a silyl sulfide compound of the general formula n n ArS--SiX.sup.1.sub.3, n n in the presence of a platinum complex catalyst. The compound, of which X is a monovalent hydrocarbon group or a hydrocarbyloxy group, can be derived from the above obtained halogen-containing compoud.

    专利号:US-10183955-B2
    优先权日:2015-07-21
    标题:Molecules for isolation of polyribosomes, ribosomes, uses and kits thereof
    发明人:CLAMER MASSIMILIANO; VIERO GABRIELLA; GUELLA GRAZIANO; QUATTRONE ALESSANDRO
    权利人:IMMAGINA BIOTECHNOLOGY S R L
    摘要:Molecules of general Formula (I): able to bind to native polyribosomes engaged in active protein synthesis. The disclosure relates also to the use of the molecules of general Formula (I) for isolating at least one active ribosome from a biological sample, and for ribosome profiling, as well as kits for isolating at least one active ribosome from a biological sample.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Enantioselective Synthesis Of Axially Chiral Biaryls By Diels-Alder/retro-Diels-Alder Reaction Of 2-Pyrones With Alkynes
    作者:Meng-Meng Xu,Xin-Yu You,Yu-Zhen Zhang,Yang Lu,Kui Tan,Limin Yang,Quan Cai |发布日期:2021.6.23
    摘要:The Enantioselective Synthesis Of Axially Chiral Biaryls By A Copper-Catalyzed Diels-Alder/retro-Diels-Alder Reaction Of 2-Pyrones With Alkynes Is Reported Herein. Using Electron-Deficient 2-Pyrones And Electron-Rich 1-Naphthyl Acetylenes As The Reaction Partners, A Broad Range Of Axially Chiral Biaryl Esters Are Obtained In Excellent Yields (Up To 97% Yield) And Enantioselectivities (Up To >99% Ee)

    合成参考文献


    摘要:Agrahari, A. K.; Mishra, A.; Tiwari, V. K., Science of Synthesis, (2021) , 170.
    参考文献:10.1007/s11745-006-5124-4
    摘要:Carballeira NM, Sanabria D, Cruz C, Parang K, Wan B, Franzblau S. 2,6-hexadecadiynoic acid and 2,6-nonadecadiynoic acid: novel synthesized acetylenic fatty acids as potent antifungal agents. Lipids. 2006 May;41(5):507–11.
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