CAS: 23866-72-0; Ethyl 7-Hydroxy-4-Oxo-4H-Chromene-2-Carboxylate

上下游产品

CAS号89-84-9 2',4'-二羟基苯乙酮 | CAS号95-92-1 草酸二乙酯 | CAS号60-29-7 乙醚 | CAS号30113-83-8 7-hydroxy-4-oxo... | CAS号14736-31-3 4-氧代-4H-1-苯并吡喃-... | CAS号96566-25-5 阿鲁司特 | CAS号38322-74-6 ethyl 7-methoxy...

📜草酸二乙酯置于盐酸,Sodium Ethanolate体系中,用 乙醇,二氯甲烷,水 用作溶剂,以68%的收率获得7-羟基-4-氧代-4H-苯并吡喃-2-羧酸乙酯
参考文献:Chroman And Benzofuran Derivatives As 5-Hydroxytryptamine-6 Ligands
标题:Chroman And Benzofuran Derivatives As 5-Hydroxytryptamine-6 Ligands
摘要:本发明提供了一种i式化合物及其用途,用于治疗与或受5-Ht6受体相关的疾病.

专利信息

专利号:RU-2179556-C2
优先权日:1997-12-30
标 题 :DERIVATIVES OF 7-[3-[4-(6-FLUOROBENZO[D]ISOXAZOL-3-YL)-PIPERIDINE-1-YL]PROPOXY]- CHROMEN-4-ONE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION FOR INHIBITION OF D2-, 5-HT2a- AND H1-RECEPTORS AND METHOD OF INHIBITION OF D2-, 5-HT2a- AND H1-RECEPTORS IN TREATMENT OF PSYCHOSIS AND SCHIZOPHRENIA

专利号:US-4609744-A
优先权日:1983-04-21
标题 :4-oxo-benzopyran carboxylic acids
发明人：YOUNG ROBERT N; ROKACH JOSHUA; WILLIAMS HAYDN R; KAKUSHIMA MASATOSHI; GUINDON YVAN
权利人:MERCK FROSST CANADA INC
摘要:Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are leukotriene antagonists. These compounds inhibit SRS-A and leukotriene synthesis and are antagonists of SRS-A and are thus useful in the treatment of asthma, allergic disorders, inflammation, skin diseases and certain cardiovascular disorders.