CAS: 2216-12-8; 1-Nitro-2-Phenoxybenzene
该化合物其结构特征为两枚苯基环,通过一个醚链接连接,并有一个硝基苯基组,该化合物一般是黄色至褐色固体,以水中的溶性较低而著称,同时在乙醇和丙酮等有机溶剂中更易溶解,显示出硝基化合物的典型特性,包括潜在的反应性能以及参与电子生物替代反应的能力. 2-硝基苯醚经常用于各种化学合成,并可作为染料,药品和其他有机化合物生产的中间体.由于硝基化合物的存在,该化合物还可能表现出一定程度的毒性和环境持久性,因此需要根据安全条例谨慎处理和处置.
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号88-73-3 邻氯硝基苯 | CAS号108-95-2 苯酚 | CAS号577-19-5 邻溴硝基苯 | CAS号609-73-4 邻硝基碘苯 | CAS号108-86-1 溴苯 | CAS号88-75-5 邻硝基苯酚 | CAS号1095-03-0 硼酸三苯酯 | CAS号15163-59-4 potassium ortho... | CAS号591-50-4 碘苯 | CAS号2688-84-8 2-氨基二苯醚 | CAS号39145-47-6 4’-氯-2-硝基二苯醚 | CAS号2244-56-6 11-Phenyl-10,11... | CAS号2688-85-9 2-苯氧基苯磺酰氯 | CAS号2868-49-7 11-Methyldibenz... | CAS号56966-62-2 1-(4-溴苯氧基)-2-硝基苯 | CAS号2770-11-8 4'-氯-2-氨基-二苯醚 | CAS号34883-46-0 2-碘二苯醚 | CAS号143359-96-0 N-(2-phenoxyphe... | CAS号15822-77-2 1-(2-硝基苯基)哌啶 | CAS号2592-95-2 1-羟基苯并三唑合成工艺路线路线简述
📜Potassium Phenolate置于硝酸,铜,溶剂黄146体系中,化学反应生成2-硝基苯基苯基醚
参考文献:Lock,Monatshefte Fur Chemie,1930,Vol. 55,P. 167,179
标题:Lock,Monatshefte Fur Chemie,1930,Vol. 55,P. 167,179
海关参考信息
- 2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸
2909199090-其他醚及其衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-4476315-A
优先权日:1982-04-30
标 题:Nucleophilic substitution process
发明人：STAHLY G PATRICK; STAHLY BARBARA C
权利人:ETHYL CORP
摘要:Nitroarylacetic acid esters are prepared by reacting a nitroaromatic compound which is devoid of halogen on the aromatic ring carrying a nitro group with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base so that the ester undergoes a nucleophilic substitution on an unsubstituted ring carbon of the nitroaromatic compound during which an alpha-substituent functions as a leaving group. Nitrobenzene acetic acids and their esters are useful intermediates for the synthesis of pharmaceuticals.
专利号:US-4499026-A
优先权日:1982-08-25
标题 :Nucleophilic substitution process
发明人：STAHLY BARBARA C; STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Nitroarylacetonitriles are prepared by reacting a nitroaromatic compound which is devoid of halogen on the aromatic ring carrying a nitro group with an alpha,alpha-disubstituted acetonitrile in an inert solvent and in the presence of a base so that the nitrile undergoes a nucleophilic substitution on an unsubstituted ring carbon of the nitroaromatic compound during which an alpha-substituent functions as a leaving group. Nitrobenzene acetic acids and their nitriles are useful intermediates for the synthesis of pharmaceuticals.
专利号:US-4511729-A
优先权日:1982-04-30
标 题 :Nucleophilic substitution process
发明人：STAHLY G PATRICK; STAHLY BARBARA C
权利人:ETHYL CORP
摘要:Nitrophenoxy- or nitrophenylthiobenzeneacetic acid esters are prepared by reacting a nitrophenoxy- or nitrophenylthiobenzene with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base. The products are useful as intermediates for the synthesis of pharmaceuticals, such as fenoprofen.
专利号:US-4502998-A
优先权日:1982-08-25
标题 :Nucleophilic substitution process
发明人：STAHLY BARBARA C; STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Nitrophenoxy- or phenylthiobenzeneacetonitriles are prepared by reacting a nitrophenoxy- or nitrophenylthiobenzene with an alpha,alpha-dinitrosubstituted acetonitrile in an inert solvent and in the presence of a base. The products are useful as intermediates for the synthesis of pharmaceuticals, such as fenoprofen.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Toxicology., 8(347), 1977 []
摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
摘要:Thomas, A. W., Science of Synthesis, (2007) 31, 512.
摘要:Thomas, A. W., Science of Synthesis, (2007) 31, 496.
摘要:Urgaonkar, S.; Verkade, J. G., Science of Synthesis, (2009) 42, 930.
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