CAS: 1595-05-7; 1-Butyl-4-Methylbenzene

上下游产品

n-butyllithium para-bromotoluene 1-(4-methylphenyl)butan-1-one 1-butyl-4-(chloromethyl)benzene 5-n-butyl-8-methyl-1,2,3,4-tetraphenylnaphthalene methyl (S)-2-(4-bromophenyl)-3-(4-butylphenyl)propanoate

📜4-碘苄醇置于盐酸,三乙胺体系中,用 四氢呋喃,二氯甲烷 用作溶剂,化学反应 0.5H,反应生成4-正丁基甲苯
参考文献:苄基位置带有离去基团的芳基锌酸酯的新的1,2-迁移:应用于对位碘苄基衍生物,三烷基锌酸酯和亲电试剂的三组分偶联,导致官能化的对位取代苯
标题:苄基位置带有离去基团的芳基锌酸酯的新的1,2-迁移:应用于对位碘苄基衍生物,三烷基锌酸酯和亲电试剂的三组分偶联,导致官能化的对位取代苯
摘要:描述了对碘苄基衍生物,三烷基锌酸酯和亲电试剂的三组分偶联.三烷基锌酸锂(r 3 Znli)与对碘苄基甲烷磺酸酯反应,得到苄基锌试剂对-Rc 6 H 4 Ch 2 Zn(l).该反应通过涉及初始碘/锌交换和所得芳基锌酸酯的1,2-迁移的机理进行.如此制得的苄锌试剂随后用于与亲电子试剂如醛,酮,酰氯,甲苯磺酰氰和氯硅烷的偶合反应,得到各种官能化的p取代的苯.在barbier条件下的反应,其中在亲电子试剂的存在下生成相应的苄基锌试剂,对于me 3 Znli和衍生自grignard试剂的锌酸镁r 3 Znmgbr效果很好.从二乙基1-(对碘苯基)乙基磷酸酯开始的仲苄基锌试剂的产生以及它们与亲电试剂的反应也在巴比尔条件下实现.在这些条件下,酮,烯丙基溴和氯硅烷已成功用作亲电子试剂.
Doi:10.1016/s0040-4020(98)00569-9

专利信息

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:US-2015336866-A1
优先权日:2013-01-01
标题:Synthesis of difluoromethyl ethers and sulfides
发明人：HARTWIG JOHN; FIER PATRICK
权利人:UNIV CALIFORNIA
摘要:The synthesis of difluoromethyl ethers and sulfides with a simple, non-ozone-depleting reagent is described. The difluoromethylation of phenols with this reagent occurs at room temperature within minutes with exceptional functional group tolerance. The mild conditions makes possible tandem processes for the conversion of aryl boronic acids, aryl halides and arenes to difluoromethyl ethers. Mechanistic studies support a reaction pathway involving nucleophilic attack of the phenolate to difluorocarbene.

专利号:US-6245937-B1
优先权日:1996-11-29
标题 :Liquid phase parallel synthesis of chemical libraries
发明人：CHENG SOAN; SAUNDERS JOHN
权利人:DUPONT PHARMACEUTICALS RES LAB
摘要:This invention features methods of biphasic synthesis for synthesizing combinatorial libraries and combinatorial libraries of chemical compounds utilizing the template, and combinatorial libraries of chemical compounds formed by the methods of this invention.

专利号:US-6608196-B2
优先权日:2001-05-03
标题 :Process for solid supported synthesis of pyruvate-derived compounds
发明人：WANG BING; JANAGANI SATYANARAYANA; CALLAWAY WYETH B; SESSLER JONATHAN L
权利人:GALILEO PHARMACEUTICALS INC
摘要:Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.

专利号:US-10940467-B2
优先权日:2014-01-27
标 题 :Synthesis of molecular sieves having MWW framework structure
发明人：JOHNSON IVY D; HRYCENKO NADYA A
权利人:EXXONMOBIL CHEMICAL PATENTS INC
摘要:The present invention provides an improved method for making molecular sieves having MWW framework structure using precipitated aluminosilicates (PAS), and the use of molecular sieves so made in processes for catalytic conversion of hydrocarbon compounds.

专利号:US-7833926-B2
优先权日:2005-07-01
标题 :Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins
发明人：WOO TAE WOO; OK MYUNG AHN; HAHN JONG SOK; LEE MAL-OU; KANG SANG OOK; KO SUNG-BO; KIM TAE-JIN; KIM SUNG-KWAN
权利人:SK ENERGY CO LTD
摘要:The present invention relates to an arylphenoxy catalyst system producing an ethylene homopolymer or copolymers of ethylene and α-olefins, and a method of producing an ethylene homopolymer or copolymers of ethylene and α-olefins having a high molecular weight under a high temperature solution polymerization condition using the same. The catalyst system includes a group IV arylphenoxy-based transition metal catalyst and an aluminoxane cocatalyst or a boron compound cocatalyst. In the transition metal catalyst, a cyclopentadiene derivative and arylphenoxide as fixed ligands are located around the group IV transition metal, arylphenoxide is substituted with at least one aryl derivative and is located at the ortho position thereof, and the ligands are not crosslinked to each other. The catalyst includes an environmentally-friendly raw material, synthesis of the catalyst is economical, and thermal stability of the catalyst is excellent. It is useful for producing an ethylene homopolymer or copolymers of ethylene and α-olefins having various physical properties in commercial polymerization processes.