CAS: 1225-20-3; Iothalamate Sodium

该化合物是一种主要用于医疗成像的放射性对比剂,特别是在静脉脉冲成像和计算成色扫描等程序中使用的抗辐射剂;一种含碘的可溶水化合物,由于原子数量高,提高了X射线成像内部结构的可见度;该物质是白色的,是白色的,一般是静脉喷发的;异丙氨酸钠的特征是能够吸收X光,使其对血管和器官具有可视效果;必须指出,它与其他碘化反光剂一样,可能会对某些病人造成过敏反应,并可能影响肾功能,特别是在有肾病前症状的病人中,该化合物一般都具有良好的调理作用,但医务人员必须评估使用前的风险和好处;此外,必须遵守适当的剂量准则,以尽量减少可能的副作用.

结构式图片

MSDS等安全信息

    合成工艺路线路线简述

      海关参考信息

      专利信息


      专利号:US-7048907-B2
      优先权日:2001-02-05
      标题 :Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products
      发明人:GROMAN ERNEST V; REINHARDT CHRISTOPHER P
      权利人:BIOPHYSICS ASSAY LAB INC
      摘要:Stable isotope labeling and neutron activation to measure biological functions are provided, as are the use and method of adding a chemical monitor to correct for neutron flux to sample vials prior to the addition of sample is presented, and the use of stable isotopes as a chemical bar code for vials and other items. Methods are provided also for measuring glomerular filtration rate and glomerular sieving function in a subject, and for measuring other physiological functions.

      专利号:US-2003059368-A1
      优先权日:2001-02-05
      标 题 :Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products

      专利号:WO-2011059609-A9
      优先权日:2009-10-13
      标 题 :Dendrimer compositions and methods of synthesis

      专利号:WO-2011028334-A2
      优先权日:2009-08-26
      标题:Synthesis and isolation of dendrimer systems

      专利号:US-2006067881-A1
      优先权日:2001-02-05
      标题 :Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products

      专利号:US-2014315720-A1
      优先权日:2012-10-24
      标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
      发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
      权利人:CELANESE ACETATE LLC
      摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      主要参考文献


      1: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Iothalamate. 2018 Oct 31. 67(1):49-55. doi: 10.1053/j.ajkd.2015.08.020. Epub 2015 Oct 9. 67(6):991. doi: 10.1053/j.ajkd.2015.12.035. 68(2):329-330. doi: 10.1053/j.ajkd.2016.01.007. Epub 2016 Feb 3. 2006–. Iothalamate Sodium I 125. 2019 Jun 30. 37(17-18):2363-7. doi: 10.1002/elps.201600084. Epub 2016 Jul 4.
      10:80. doi: 10.1186/s13065-016-0227-3.
      8: Capuano V, Quintiliani M, Sapora O, Simone G. Radiation chemical and physical mechanisms of radiosensitization of single cell systems by iothalamate. Int J Radiat Biol Relat Stud Phys Chem Med. 1986 Sep;50(3):481-90. doi: 10.1080/09553008614550891. 67(6):991-2. doi: 10.1053/j.ajkd.2016.02.055. 56(4):568-74. doi: 10.1373/clinchem.2009.133751. Epub 2010 Feb 18.

      合成参考文献


      摘要:Journal of Medicinal Chemistry., 6(24), 1963
      参考文献:10.1007/bf02551958
      摘要:Rajani M, Shrivastava S, Tandon R, Bhargava S. Right ventricular cineangiography in tetralogy of Fallot. CardioVascular and Interventional Radiology. 1980 Feb;3(1):13–7. doi: 10.1007/bf02551958.
      📝 需求与反馈
      尽可能描述清楚需求与问题信息
      ×

      通知