CAS: 1126-46-1; Methyl 4-Chlorobenzoate

相似化合物

104-88-1 74-11-3 873-76-7

上下游产品

CAS号681-84-5 原硅酸四甲酯 | CAS号104-88-1 对氯苯甲醛 | CAS号75-91-2 叔丁基过氧化氢 | CAS号67-56-1 甲醇 | CAS号106-39-8 对氯溴苯 | CAS号201230-82-2 carbon monoxide | CAS号106-46-7 1,4-二氯苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号873-76-7 4-氯苄醇 | CAS号99768-12-4 4-甲酯基苯硼酸 | CAS号4068-78-4 5-氯水杨酸甲酯 | CAS号22717-55-1 4-氯水杨酸甲酯 | CAS号873-76-7 4-氯苄醇 | CAS号321-37-9 4'-氯-2,2,2-三氟苯乙酮 | CAS号49742-56-5 4’-甲基[1,1’-联苯]-... | CAS号53355-25-2 4-呋喃-2-苯甲酸甲酯 | CAS号35112-28-8 2,4-二氯苯甲酸甲酯 | CAS号4906-25-6 4-正丁氧苯甲酸甲酯 | CAS号3609-53-8 对乙酰基苯甲酸乙酯 | CAS号4018-82-0 4-氯-N-(4-甲氧基苯基)苯甲酰胺

4-Chloro-N-Methoxybenzamide置于n-Chloro-N-(Benzenesulfonyl)Benzenesulfonamide体系中,用 1,2-二氯乙烷 用作溶剂,以86 %的收率获得对氯苯甲酸甲酯
参考文献:使用 N-氯-N-(苯磺酰基)苯磺酰胺将 N-烷氧基酰胺转化为酯的温和方法
标题:使用 N-氯-N-(苯磺酰基)苯磺酰胺将 N-烷氧基酰胺转化为酯的温和方法
摘要:已经报道了一种从n-烷氧基酰胺合成酯的有效,快速的方法.该方案使用容易获得的n-氯-N-(苯磺酰基)苯磺酰胺 (Ncbsi) 将烷氧基酰胺转化为相应的酯.本方法不含金属和配体,在温和的反应条件下进行.这种转化结合了多种酰胺,由芳基或烷基羧酸制备,导致功能化酯的形成,突出了其多功能性,化学选择性和高产率方面.
Doi:10.1016/j.Tetlet.2023.154539

专利信息

专利号:US-8987504-B2
优先权日:2010-06-18
标题 :Aminohydroxylation of alkenes
发明人：MEE SIMON PETER HAROLD; LUXENBURGER ANDREAS; HARRIS LAWRENCE DANIEL
权利人:MEE SIMON PETER HAROLD; LUXENBURGER ANDREAS; HARRIS LAWRENCE DANIEL; VICTORIA LINK LTD
摘要:The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds.

专利号:US-8530689-B2
优先权日:2008-05-05
标 题 :Processes for the preparation of biphenyl compounds
发明人：PERCEC VIRGIL; ROSEN BRAD MATTHEW; WILSON DANIELA A; WILSON CHRISTOPHER J
权利人:PERCEC VIRGIL; ROSEN BRAD MATTHEW; WILSON DANIELA A; WILSON CHRISTOPHER J; UNIV PENNSYLVANIA
摘要:The invention concerns processes for the synthesis of a compound of the formula: wherein: R 1 and R 2 are each, independently, C 1 -C 12 alkyl, CO 2 R 3 , OR 4 , R 5 (OR 6 ), or C 6 -C 18 aryl; R 3 -R 6 are each, independently, C 1 -C 12 alkyl or C 6 -C 12 aryl; and n and m are each, independently, O or an integer from 1-5; said process comprising:—contacting a compound of the formula H0-R 7 -0H with BH 3 and a compound of the formula in the presence of a nickel-containing catalyst to produce a first product, where R 7 is a C 2 -C 12 hydrocarbon group and X is a halogen, OMs or OTs;—contacting the first product in situ with a compound of the formula: in the presence of a nickel-containing catalyst to produce a compound of formula I, where Z is a halogen.

专利号:WO-2014027658-A1
优先权日:2012-08-13
标题 :INTERMEDIATE FOR SYNTHESIS OF 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL) CYTOSINE, INTERMEDIATE FOR SYNTHESIS OF THIONUCLEOSIDE, AND METHODS FOR PRODUCING THESE INTERMEDIATES

专利号:ES-2718307-T3
优先权日:2012-08-13
标题 :Intermediate for the synthesis of 1- (2-deoxy-2-fluoro-4-thio-beta-d-arabinofuranosyl) cytosine, intermediate for the synthesis of thionucleoside and methods to produce these intermediates

专利号:US-2010035867-A1
优先权日:2006-07-11
标 题 :Inhibitors of Cyclic Nucleotide Synthesis and Their Use for Therapy of Various Diseases
发明人：GUERRANT RICHARD L; KOTS ALEXANDER Y; MURAD FERID; CHOI BYUNG-KWON
权利人:GUERRANT RICHARD L; KOTS ALEXANDER Y; MURAD FERID; CHOI BYUNG-KWON
摘要:We disclose a method of inhibiting activity of adenylyl cyclase or guanylyl cyclase in a mammal by administering to the mammal an amount of a composition effective to inhibit the activity, wherein the composition contains at least one compound selected from the group consisting of structural formulae (Ia) and (Ib) and salts thereof, wherein R1 is —H or has the structure —C(â•?O)R8; R2 is â•?O or has the structure —OC(â•?O)R9; and R3, R4, R5, R6, and R7 are each independently selected from the group consisting of —H, —NO 2 , formula (I), -halogen, —OC(â•?O)R9, —OR9, —OH, —R8OH, —CH 3 , —OC(â•?O)CH 2 Ph, formulae (II), (III), (IV), —OPh, —CF 3 , —R8, —C(â•?O)OR9, -Ph, —R8Ph, formulae (V), (VI), (VII), (VIII), (IX), (X), (XI), (XII), (XIII), (XIV), (XV), (XVI), (XVII), (XVIII), (XIX), (XX), and (XXI), wherein each R8 is independently a linear or branched hydrocarbon group having from 1 to 4 carbon atoms and each R9 is independently a hydrocarbon group having from 1 to 2 carbon atoms. Administering the composition can be used to treat a disease in a mammal mediated by activity of adenylyl cyclase or guanylyl cyclase and effected by a toxin produced by a pathogenic organism or to reduce cyclic AMP or cyclic GMP levels in a mammal in need of reduction thereof. The composition can also be administered to mammalian cells in vitro. The above methods of inhibiting activity of adenylyl cyclase or guanylyl cyclase and treating diseases via such inhibition can be effective without prolonged treatment, have reversible effects, have low or no toxicity, are highly potent, are unlikely to have side effects, do not act on purinergic recptors, or can negate pathogenic toxins independently of whether the pathogenic organism survives.

专利号:US-2023174496-A1
优先权日:2020-05-06
标 题:Synthesis of Vinylic Protected Alcohol Intermediates