CAS: 77987-49-6; Benzyl (2-Hydroxyethyl)Carbamate

该化合物是乙醇胺的一种受保护衍生物,其特点是一个加强合成应用稳定性和选择性的苯氧碳基(Cbz)组,该组在丙二烯合成和有机化学方面特别有用,Cbz组在其中充当阿米因的临时保护组,能够在温和条件下进行控制反应.其晶状固体形式确保了处理和储存的便利性,而其明确界定的再活动特征则使它成为建造复杂分子结构的可靠中间体.产品与标准非保护方法的兼容性进一步凸显了其在多步合成工作流程中的实用性.

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欧盟法规

ECHA物质C&L通报

上下游产品

CAS号141-43-5 2-氨基乙醇 | CAS号501-53-1 氯甲酸苄酯 | CAS号1885-14-9 氯甲酸苯酯 | CAS号13139-17-8 苯甲氧羰酰琥珀酰亚胺 | CAS号2002-24-6 盐酸乙醇胺 | CAS号1138-80-3 N-苄氧羰基甘氨酸 | CAS号55378-79-5 2-(((benzyloxy)... | CAS号1145-80-8 |N|-苄氧羰基-L-丝氨酸 | CAS号100-51-6 苯甲醇 | CAS号18877-96-8 benzyl N-(2-cya... | CAS号226569-28-4 [2-(苄氧基羰基氨基)乙氧基]胺 | CAS号72080-83-2 N-Cbz-1,,2-二氨基乙烷 | CAS号103989-20-4 benzyl 2-oxo-1,... | CAS号67561-03-9 Benzyl (2-oxoet... | CAS号1138-80-3 N-苄氧羰基甘氨酸 | CAS号1170-76-9 N-苄氧羰基甘氨酰-L-苯丙氨酸 | CAS号141-43-5 2-氨基乙醇 | CAS号134307-72-5 2-(phenylmethox... | CAS号168827-96-1 N-[2-(苄氧基羰基氨基)乙...

合成工艺路线路线简述

    📜氯甲酸苄酯置于碳酸氢钠,C.I.酸性橙108体系中,用 水 作为反应溶剂,化学反应 3.0H,以71.1%的收率获得产物2-苄氧羰基氨基-1-乙醇
    参考文献:Combinations Of &bgr;3 Agonists And Growth Hormone Secretagogues
    标题:Combinations Of &bgr;3 Agonists And Growth Hormone Secretagogues
    摘要:这项发明涉及包括β3肾上腺素受体激动剂在内的药物组合物,其中包括(4-(2-(2-(6-氨基吡啶-3-基)-2(R)-羟乙基氨基)乙氧基)苯乙酸)和生长激素或生长激素促分泌剂,以及这些化合物或其前药的药用可接受盐.该发明还涉及使用这些组合物治疗动物中的肥胖,糖尿病,高血压和衰弱,特别是在人类中的方法.

    海关参考信息

    专利信息


    专利号:US-8673885-B1
    优先权日:2010-07-25
    标 题 :Compounds for the protection of sulfur containing linkers in nucleic acid synthesis
    发明人:DUFF ROBERT
    权利人:DUFF ROBERT
    摘要:Aromatic and alkyl thiocarbonates with and without a neighboring group that participates in the hydrolysis of a thiocarbonate are described. The aromatic or alkyl thiocarbonates can be used for the protection of sulfur during oligonucleotide synthesis. Their facile processes of manufacture and methods of using the same are provided.

    专利号:US-2005148042-A1
    优先权日:2002-03-29
    标 题 :Hybrid phosphoinositide phospholipids: compositions and uses
    发明人:PRESTWICH GLENN; RZEPECKI PIOTR W; FERGUSON COLIN G; NEILSEN PAUL O; BRANCH ANGIE M; CROSBY LEE R
    摘要:The methods and compositions disclosed herein concern the synthesis of a novel class of “two-headedâ€? phospholipid-phosphoinositide hybrids possessing a carbon backbone, such as 2,3-diacylthreitol, erythritol or a synthetic module. The second phospholipid head group allows introduction of a biochemical or chemical moiety in a position orthogonal in space to those occupied by the phosphoinositide head group and the two acyl chains. The diacyl moieties allow for the incorporation of Pea-PIP 2 into a lipid bilayer, while the Ptdlns(4,5)P 2 moiety in the aqueous layer is specifically recognized by lipid binding proteins. In alternative embodiments of the invention, reporters, for example biotin, fluorophores and/or spin labels, are attached to the free amino group of the head groups of such molecules to specifically target the reporters to the lipid-water interface.

    专利号:US-8450414-B2
    优先权日:2007-01-30
    标题 :Glycerol ester-free functionalized vegetable oil derivatives and their latex compounds
    发明人:THAMES SHELBY F; RAWLINS JAMES W; MENDON SHARATHKUMAR K; DELATTE DAVID
    权利人:THAMES SHELBY F; RAWLINS JAMES W; MENDON SHARATHKUMAR K; DELATTE DAVID; UNIV SOUTHERN MISSISSIPPI
    摘要:The present invention is directed to a fatty amide (meth)acrylate monomer, methods of making the monomer, and latex polymers comprising the fatty amide (meth)acrylate monomer. The monomers are derived by reacting unsaturated vegetable oils with ethanolamine or substituted ethanolamine. The vegetable oil derivative is then reacted with either (meth)acryloyl chloride or (meth)acrylic acid to form a fatty amide (meth)acrylate monomer or the product of the reaction of hydroxyethyl (meth)acrylate reacted with isophorone diisocyanate to form a urethane fatty amide (meth)acrylate monomer. The increased hydrophilicity of the fatty amide (meth)acrylate monomer facilitates the diffusion through the aqueous phase. The monomer synthesis is designed to be glycerol ester-free to increase long term stability for monomers and polymers.

    专利号:CN-115093365-A
    优先权日:2022-07-25
    标题:Synthesis method of lefenacin

    专利号:CN-116813518-A
    优先权日:2023-05-09
    标 题 :Synthesis method of nemaltevir chiral intermediate

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Alkyl 1-Chloroalkyl Carbonates: Reagents For The Synthesis Of Carbamates And Protection Of Amino Groups
    作者:Gérard Barcelo,Jean-Pierre Senet,Gérard Sennyey,Jean Bensoam,Albert Loffet
    摘要:The Synthesis Of 1-Chloroalkyl Carbonates And Their Reaction With Various Type Of Amines Are Described. This Reaction Is Useful For The Synthesis Of Carbamate Pesticides And For The Protection Of Various Amino Groups, Including Amino Acids.

    合成参考文献


    参考文献:10.1007/s12010-012-0056-3
    摘要:Sudar M, Valinger D, Findrik Z, Vasić-Rački Đ, Kurtanjek Ž. Effect of Different Variables on the Efficiency of the Baker's Yeast Cell Disruption Process to Obtain Alcohol Dehydrogenase Activity. Applied Biochemistry and Biotechnology. 2013 Jan 09;169(3):1039–55. doi: 10.1007/s12010-012-0056-3.
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