CAS: 6968-72-5; 3-(Hydroxymethyl)Pyridine 1-Oxide

上下游产品

3-hydroxymethylpyridin tetramethlyammonium chloride 3-(chloromethyl)pyridine N-oxide 3-Acetoxymethylpyridine-N-oxide 3-hydroxymethylpyridin 3-pyridinecarboxaldehyde

📜3-吡啶甲醇置于间氯过氧苯甲酸体系中,用 氯仿 作为反应溶剂,化学反应 12.0H,以76%的收率获得产物3-吡啶甲醇氮氧化物
参考文献:Nagano,Hiroyuki; Nawata,Yoshiharu; Hamana,Masatomo,Chemical And Pharmaceutical Bulletin,1987,Vol. 35,# 10,P. 4068-4077
标题:Nagano,Hiroyuki; Nawata,Yoshiharu; Hamana,Masatomo,Chemical And Pharmaceutical Bulletin,1987,Vol. 35,# 10,P. 4068-4077

专利信息

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-3753970-A
优先权日:1970-08-04
标题:Cyclopeptides derived from polymyxins and their preparation
发明人：BOUCHAUDON J; JOLLES G
权利人:RHONE POULENC SA
摘要:THE NEW CYCLOPEPTIDES OF THE FORMULA: DAB<(-DAB(-G)-Y-Z-DAB(-G)-DAB(-G)-THR-) IN WHICH Y-Z REPRESENTS AN AMINO ACID CHAIN SELECTED FROM D-LEU-THR,D-PHE-LEU, D-LEU-LEU AND D-LEU-ILEU, G REPRESENTS AN AMINO-PROTECTING RADICAL OF THE FORMULA: PY-CH(-R)-OOC- IN WHICH PY REPRESENTS PYRIDYL, PYRIDYL-N-OXIDE, OR PYRIDYL OR PYRIDYL-N-OXIDE CARRYING A METHYL SUBSTITUENT, R REPRESENTS HYDROGEN, ALKYL OF 1 TO THROUGH 5 CARBON ATOMS, OR PHENYL, AND DAB REPRESENTS A,Y-DIAMINOBUTYRIC AID, THE AMINO ACIDS HAVING THE L-CONFFIGURATION UNLESS OTHERWISE INDICATED, SAID CYCLOPEPTIDES CONTAINING ONLY A SINGLE FREE AMINO GROUP, ARE USEFUL INTERMEDIATES FOR THE SYNTHESIS OF SEMI-SYNTHETIC PRODUCTS DERIVED FROM POLYMYXINS.