CAS: 551-09-7; N-(1-Naphthyl)Ethylenediamine

该化合物是一种有机化合物,其结构特征包括一个附于乙二胺协会的环,该化合物一般是晶状固体,以其作为各种化学反应,特别是染料和其他有机化合物合成中的试剂而闻名,其特性表现在有机溶剂中的溶性以及在标准条件下的中度稳定性. N-(1-纳phyl)乙二胺在分析化学中的潜在用途也得到承认,特别是在色度分析以及协调化学中的可能应用.此外,该化合物可能具有生物活动,已在各种研究中加以探讨.然而,处理该化合物需要谨慎,因为其潜在毒性以及在实验室环境中需要采取适当的安全措施.

结构式图片

MSDS等安全信息

    上下游产品

    Methyl 3-(Naphthalen-1-Ylamino)Propanoate 6580-20-7
    1-萘胺 1-Amino-Naphthalene 134-32-7

    合成工艺路线路线简述

      📜N-(1-Naphthyl)Ethylenediamine Dihydrochloride置于sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应 2.0H,反应生成 N-(1-萘基)乙二胺
      参考文献:一种胱氨酸胆固醇凝胶因子及其制备方法
      标题:一种胱氨酸胆固醇凝胶因子及其制备方法
      摘要:本发明涉及一种胱氨酸胆固醇凝胶因子及其制备方法,该凝胶因子是以天然产物胆固醇以及胱氨酸为原料,通过化学反应得到的.发明还公开了一种超分子凝胶,由上述的凝胶因子在苯类溶剂,正丙醇或环己烷等溶剂中自组装得到,微观形貌为规整的纳米带或纳米纤维网络结构.本发明的凝胶因子和超分子凝胶制备过程所采用原料属于天然小分子化合物,具有来源广泛,生物相容性好,结构独特等优点,并表现出较好的离子选择性识别和还原响应特性.这样的凝胶体系具有非常好的生物相容性和环境友好性,为智能响应凝胶材料的构建提供了新的思路,也为拓展胱氨酸和胆固醇天然小分子化合物在超分子领域的应用提供了新的参考.

      海关参考信息

      专利信息


      专利号:US-11833132-B1
      优先权日:2023-06-26
      标 题 :Method of synthesis of a nanocomposite including silymarin-loaded collagen nanoparticles
      发明人:ALI MAI MOSTAFA KHALAF; AHMED HANY MOHAMED ABD EL-LATEEF; MOHAMMED AHMED MOHAMMED ABU-DIEF; SHAHEEN HAZEM MOHAMED; BATIHA GABER ELSABER ABD EL-WANIS; SHALABY MANAL ALY; ALAMH AMANY MABROUK ABD ELHADY
      权利人:UNIV KING FAISAL
      摘要:A method of synthesizing silymarin-loaded collagen collagen nanoparticles can include dissolving silymarin in an alcohol to provide a solution, mixing the solution with acetic acid to provide an acetic acid mixture, and adding the glutaraldehyde to the mixture to provide silymarin nanoparticles. The silymarin nanoparticles can be dissolved in a further alcohol and mixed for a period of time to provide a silymarin nanoparticle mixture. Then, the silymarin nanoparticles can be mixed with collagen nanoparticles to provide a silymarin/collagen mixture. Glutaraldehyde can be added to the collagen mixture to provide the nanocomposite formulation.

      专利号:US-6153615-A
      优先权日:1991-12-26
      标 题 :Blocking induction of tetrahydrobioterin to block induction of nitric oxide synthesis
      发明人:GROSS STEVEN S
      权利人:CORNELL RES FOUNDATION INC
      摘要:Guanosine triphosphate pathway tetrahydrobiopterin synthesis antagonist and/or pterin salvage pathway tetrahydrobiopterin synthesis antagonists are administered to inhibit nitric oxide synthesis from arginine in vascular cells in a subject in need of such inhibition (e.g., for prophylactic or curative effect for endotoxin- or cytokine-induced hypotension or for restoration of vascular contractile sensitivity to pressor agents in the treatment of such hypotension). The tetrahydrobiopterin synthesis antagonist may be administered with α 1 -adrenergic agonist or with nitric oxide synthase inhibitor. The tetrahydrobiopterin synthesis antagonists are also administered to attenuate inflammation caused by induced nitric oxide production in immune cells. Unwanted counterproductive or side effects can be eliminated or ameliorated by administration additionally of levodopa with or without carbidopa and L-5-hydroxytryptophane.

      专利号:US-6274581-B1
      优先权日:1991-12-26
      标 题 :Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis
      发明人:GROSS STEVEN S
      权利人:CORNELL RES FOUNDATION INC
      摘要:Guanosine triphosphate pathway tetrahydrobiopterin synthesis antagonist and/or pterin salvage pathway tetrahydrobiopterin synthesis antagonist are administered to inhibit nitric oxide synthesis from arginine in vascular smooth muscle cells in a subject in need of such inhibition (e.g. for prophylactic or curative effect for cytokine-induced hypotension or for restoration of vascular contractile sensitivity to pressor agents in the treatment of such hypotension).

      专利号:US-12012375-B2
      优先权日:2018-05-17
      标 题:Prostaglandin F2 alpha derivatives for decreasing intraocular pressure
      发明人:BEZUGLOV VLADIMIR VILENOVICH; SERKOV IGOR VIKTOROVICH; Lyubimov Igor Ivanovich; GRETSKAYA NATALIYA MIKHAILOVNA
      权利人:GURUS BIOPHARM LLC
      摘要:The invention relates to clinical chemistry, in particular, to new biologically active compounds—amide derivatives of prostaglandin F2α. These compounds have low cytotoxicity and are capable of stimulating formation of endogenous nitrogen oxide in mammal cells. Synthesis of such compounds promotes expansion of nomenclature of biologically active derivatives of prostaglandin F2α capable of reducing intraocular pressure.

      专利号:US-8323929-B2
      优先权日:1999-06-17
      标题 :Methods for detecting nucleic acid sequence variations
      发明人:WANG SHA-SHA; THORNTON KEITH; NADEAU JAMES G; HELLYER TOBIN J
      权利人:WANG SHA-SHA; THORNTON KEITH; NADEAU JAMES G; HELLYER TOBIN J; BECTON DICKINSON CO
      摘要:The invention employs an unlabeled signal primer comprising a 5′ adapter sequence for detection of variations in nucleic acid target sequences. The detection system further comprises a reporter probe, the 3′ end of which hybridizes to the complement of the 5′ adapter sequence of the signal primer to produce a 5′ overhang. Polymerase is used to fill in the overhang and synthesize the complement of the 5′ overhang of the reporter probe. Synthesis of the reporter probe complement is detected, either directly or indirectly, as an indication of the presence of the target.

      专利号:WO-2024219698-A1
      优先权日:2023-04-19
      标 题 :Composition for preventing, ameliorating, or treating arthritis, containing potentilla chinensis extract or apigenin-7-o-glucuronide as active ingredient
      发明人:JUNG BYUNG CHAN; LEE SUN HEE; LEE KYUNG-TAE; LEE SANG OK; SHIN DONG MIN
      权利人:BELABELBIO INC
      摘要:The present invention discloses a composition for preventing, ameliorating, or treating arthritis, the composition containing a Potentilla chinensis extract or apigenin-7-O-glucuronide as an active ingredient. The present invention inhibits the expression of MMP-1 and MMP-9, increases the synthesis of procollagen type 2, and not only alleviates inflammation but also inhibits inflammatory pain, and thus has the effect of preventing, ameliorating, or treating arthritis.

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      合成参考文献


      参考文献:10.1186/1471-2261-11-43
      摘要:Ajmani P, Yadav HN, Singh M, Sharma PL. Possible involvement of caveolin in attenuation of cardioprotective effect of ischemic preconditioning in diabetic rat heart. BMC Cardiovascular Disorders. 2011 Jul 12;11(1):43. doi: 10.1186/1471-2261-11-43.
      参考文献:10.1155/2011/385780
      摘要:Burnett BP, Bitto A, Altavilla D, Squadrito F, Levy RM, Pillai L. Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant. Mediators Inflamm. 2011;2011():385780.
      参考文献:10.1186/1748-717x-6-86
      摘要:He Z, Zhang H, Yang C, Zhou Y, Zhou Y, Han G, Xia L, Ouyang W, Zhou F, Zhou Y, Xie C. The interaction between different types of activated RAW 264.7 cells and macrophage inflammatory protein-1 alpha. Radiation Oncology. 2011 Jul 22;6(1):86. doi: 10.1186/1748-717x-6-86.
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