专利号:US-9024030-B2 优先权日:2012-01-13 标题 :Process for the synthesis of etoricoxib 发明人:MAO ZHENMIN; LAN TIAN; LIU LANFANG; YAN LONG; BECKER STEFAN 权利人:TIEFENBACHER ALFRED E GMBH & CO KG; SHANGHAI GOLDEN PHARMATECH CO LTD; SHANGHAI GOLDEN PHARMATECH CO LTD 摘要:The present invention relates to a process for the synthesis of the anti-inflammatory agent 5-chloro-3-(4-methanesulfonylphenyl)-6′-methyl-[2,3′]bipyridine, referred to as compound of formula (1) or etoricoxib, which is a pharmaceutically active ingredient inhibiting cyclooxygenase-2. In particular, the application concerns a novel process of making the compound of formula (1) by oxidizing a compound of formula (4).
专利号:US-2015011771-A1 优先权日:2012-01-13 标题 :Process for the synthesis of etoricoxib
专利号:EP-2802564-B1 优先权日:2012-01-13 标 题:Process for the synthesis of etoricoxib
专利号:EP-2802564-A1 优先权日:2012-01-13 标 题:Process for the synthesis of etoricoxib
专利号:WO-2013104546-A1 优先权日:2012-01-13 标 题 :Process for the synthesis of etoricoxib
专利号:CN-103204803-A 优先权日:2012-01-13 标题 :Method for the synthesis of etoricoxib