CAS: 2490-91-7; (2R,4S,5R)-2,4,5,6-Tetrahydroxyhexanal

上下游产品

3-deoxy-D-ribo-hexono-1,4-lactone 2-Deoxy-D-ribose 5-hydroxymethyl-2-furfuraldehyde

📜双丙酮葡萄糖置于咪唑,硫酸,三正丁基氢锡,Sodium Hydride体系中,用 四氢呋喃,水,甲苯 用作溶剂,化学反应 5.0H,反应生成3-脱氧-D-葡萄糖
参考文献:Reactivity Of Thermally Treated α-Dicarbonyl Compounds
标题:Reactivity Of Thermally Treated α-Dicarbonyl Compounds
摘要:The Degradation Reaction Of Thermally Treated 3-Deoxy-D-Erythro-Hexos-2-Ulose And Methylglyoxal,Both Key Intermediates In Mail Lard Chemistry,Was Investigated. Different Analytical Strategies Were Accomplished To Cover The Broad Range Of Formed Products And Their Different Chemical Behavior. These Involved HPLC-Dad And Accordingly Lc/ms Analysis Of The Quinoxaline Derivates,Gc/ms Analysis Of The Acetylated Quinoxalines,And Gc-Fid Analysis Of The Decyl Ester Of Acetic Acid. As A Main Degradation Product Of 3-Deoxy-D-Erythro-Hexos-2-Ulose,5-(Hydroxymethyl)Furfural Could Be Identified. At Alkaline Ph Values,3-Deoxy-D-Erythro-Hexos-2-Ulose Generated Various Acids But No Colored Products. In Contrast,Thermal Treatment Of Methylglyoxal Yielded High Molecular Weight,Brownish Products. A Dimer Of Methylglyoxal,First Precursor For Aldol-Based Polymerization Of Methylglyoxal,Could Be Clearly Identified By Gc/ms.
Doi:10.1021/jf302959K

专利信息

专利号:US-2009076258-A1
优先权日:2005-03-22
标 题 :Method for synthesizing oligosaccharides and glycosylation
发明人：BUCHHOLZ KLAUS; SEIBEL JURGEN; JOERDENING HANS-JOACHIM; BEINE RAPHAEL
权利人:BUCHHOLZ KLAUS; SEIBEL JURGEN; JOERDENING HANS-JOACHIM; BEINE RAPHAEL
摘要:The invention relates to an enzymatic method for synthesizing oligosaccharides, whereby one saccharide group of a sucrose analogue each is transferred onto an acceptor molecule, for example for glycosylating a hydroxyl compound, a saccharide, peptide, or a drug. According to the inventive method, an enzymatic synthesis of β-D-fructofuranosyl-a-D-aldopyranoside is carried out in a first step, and in a second step one of the saccharide groups is enzymatically transferred onto the acceptor molecule.

专利号:US-2013337485-A1
优先权日:2010-12-20
标题:Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof

专利号:CA-2822331-A1
优先权日:2010-12-20
标 题:Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof

专利号:WO-2012095244-A2
优先权日:2010-12-20
标题 :Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof

专利号:EP-2655650-A2
优先权日:2010-12-20
标题 :Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof

专利号:CN-106520864-A
优先权日:2016-09-28
标题:A kind of method and application of enzymatic synthesis of sialic acid analogs