CAS: 2040-95-1; Butylcyclopentane

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CAS号137-43-9 溴代环戊烷 | CAS号1556-18-9 碘环戊烷 | CAS号693-04-9 正丁基氯化镁 | CAS号109-72-8 正丁基锂 | CAS号3558-06-3 1-cyclopentylox... | CAS号120-92-3 环戊酮 | CAS号623-11-0 对硝基甲苯 | CAS号2423-01-0 1-butylcyclopentene | CAS号3637-15-8 5-氧代壬酸 | CAS号107-92-6 正丁酸 | CAS号109-52-4 正戊酸 | CAS号98-82-8 异丙基苯 | CAS号96-37-7 甲基环戊烷 | CAS号100-41-4 乙苯 | CAS号103-65-1 正丙苯溶液标准物质 | CAS号2234-75-5 1,2,4-三甲基环己烷 | CAS号611-14-3 邻乙基甲苯 | CAS号2216-34-4 4-甲基辛烷

📜碘代环戊烷置于li2[di-N-Butylcyanocuprate]体系中,用 四氢呋喃 用作溶剂,化学反应 2.0H,以82%的收率获得正丁基环戊烷
参考文献:Substitution Reactions Of Secondary Halides And Epoxides With Higher Order,Mixed Organocuprates,R2Cu(Cn)Li2: Synthetic,Stereochemical,And Mechanistic Aspects
标题:Substitution Reactions Of Secondary Halides And Epoxides With Higher Order,Mixed Organocuprates,R2Cu(Cn)Li2: Synthetic,Stereochemical,And Mechanistic Aspects
摘要:
Doi:10.1021/jo00195A009

专利信息

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:US-9845282-B1
优先权日:2016-08-12
标题 :Palladium catalyzed synthesis of ester compounds
发明人：EL ALI BASSAM M; IBRAHIM MANSUR B; SULEIMAN RAMI K
权利人:UNIV KING FAHD PET & MINERALS
摘要:A catalytic process for synthesizing an ester compound, and a catalytic process for synthesizing an amide compound, wherein a solid-supported palladium catalyst is used to catalyze an alkoxycarbonylation reaction of an aryl halide to form the ester compound, or to catalyze an aminocarbonylation reaction of an aryl halide to form the amide compound. Various embodiments of each of the processes are also provided.

专利号:EP-0458971-B1
优先权日:1989-12-05
标题:Inosine guanosine kinase
发明人：MORI HIDEO; IIDA AKIHIRO; TESHIBA SADAO; FUJIO TATSURO
权利人:KYOWA HAKKO KOGYO KK
摘要:A new inosine guanosine kinase (IGK) catalyses the synthesis of 5'-inosinic acid from inosine and ATP or from inosine and deoxyadenosine triphosphate (dATP); and the synthesis of 5'-guanylic acid from guanosine and ATP or from guanosine and dATP. The structure of the enzyme is given (454 amino acid residues); its mol.wt. is 48400. The working pH is 6.9-8.2 and working temp. 25-40 deg.C. The enzyme is stable over the range pH 6.6-9.0 for 16 hrs. at 4 deg.C and for 15 min. at 40 deg.C and pH 7.2. It is inhibited by Co2+, Cu2+ or Zn2+ but activated by K+/Mg2+ or K+/Mn2+. Also claimed is a DNA sequence coding for the enzyme; such DNA incorporated in a suitable vector; and transformant organisms (esp. of E. coli) incorporating the vector.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-5270301-A
优先权日:1989-05-08
标 题:Fluoro-amide derivatives
发明人：WOLANIN DONALD J
权利人:ICI AMERICA INC
摘要:The present invention relates to certain fluoro-amide derivatives, of the general formula which are human leukocyte elastase (HLE) inhibitors making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated, including treatment of tissue degenerative diseases such as pulmonary emphysema. The invention also includes intermediates useful in the synthesis of these fluoro-amide derivatives, processes for preparing them, pharmaceutical compositions containing such peptide derivatives and methods for their use.