CAS: 19819-95-5; 2-(2-Chlorophenyl)Ethanol

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CAS号2444-36-2 2-氯苯乙酸 | CAS号2039-87-4 2-氯苯乙烯 | CAS号26059-40-5 2-(2-碘苯基)-1-乙醇 | CAS号40400-15-5 2-碘苯基乙腈 | CAS号18698-96-9 2-碘苯乙酸 | CAS号40061-54-9 邻氯苯乙酸乙酯 | CAS号4251-63-2 2-氯苯乙醛 | CAS号89-98-5 邻氯苯甲醛 | CAS号496-16-2 2,3-二氢苯并呋喃 | CAS号95-49-8 邻氯甲苯 | CAS号2039-87-4 2-氯苯乙烯 | CAS号7315-17-5 邻氯苯丙腈 | CAS号6809-91-2 1-氰基苯并环丁烯 | CAS号1005-06-7 1-(2-Chloroethy... | CAS号1643-28-3 3-(2-氯苯基)丙酸 | CAS号16793-91-2 2-氯苯乙基溴

邻氯苯乙酸乙酯置于lithium Aluminium Tetrahydride体系中,用 甲醇 用作溶剂,化学反应 1.0H,反应生成2-氯苯乙醇
参考文献:二羟基嘧啶化合物及其应用
标题:二羟基嘧啶化合物及其应用
摘要:本发明提供了一种二羟基嘧啶化合物,其结构通式为:其中,R1为含有取代基的芳基,含有取代基的杂环或c1‑c6的烷基;R2为c1‑c6的烷基,C1‑c6的烷基芳基,C1‑c6的烷基杂环或氢原子;X,Y各自为介于0‑6之间的任意自然数.本发明还提供了一种二羟基嘧啶化合物在制备抗流感病毒的药物中的应用.本发明提供的二羟基嘧啶类化合物对流感病毒活性有较好的抑制作用,能显著降低流感病毒的毒性,且细胞毒性较低,从而可以将这类化合物用于制备抗流感病毒药物.

专利信息

专利号:US-4713383-A
优先权日:1984-10-01
标 题:Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
发明人：FRANCIS JOHN E; GELOTTE KARL O
权利人:CIBA GEIGY CORP
摘要:[1,2,4]triazolo[1,5-c]quinazoline compounds of the formula wherein R1 is optionally substituted phenyl, pyridyl, furyl thienyl, dihydro or tetrahydro furanyl or thienyl, pyranyl, or 0-ribofuranosyl; R2 is hydrogen or lower alkyl; X is oxygen or NR3, R3 is as defined in the claims, and ring A is unsubstituted or substituted as set forth in the claims. The compounds wherein X is N-R3 are especially useful as adenosine antagonists and for the treatment of asthma. The compounds wherein X is oxygen are useful as benzodiazepine antagonists and as intermediates in the synthesis of the compounds wherein X is N-R3.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:CN-117821525-A
优先权日:2024-02-20
标题:A method for the enzymatic synthesis of chiral building blocks of halogen alcohol drugs

专利号:US-5145865-A
优先权日:1989-04-19
标 题 :Phenylcarboxylic acid derivatives having hetero ring
发明人：FUJII SETSURO; FUJII ADMINISTRATOR BY SHINICH; TAKADA ADMINISTRATOR BY KAORUK; KAWAMURA HIROYUKI; WATANABE SHINICHI
权利人:OTSUKA PHARMA CO LTD
摘要:Phenylcarboxylic acid derivatives having a hetero ring in the substituent of the formula: ##STR1## wherein R 1 is halogen, alkyl, cycloalkyl, hydroxy, alkoxy, phenoxy which has a substituent selected from halogen and alkyl, carboxyl, alkylsulfonyloxy, phenylsulfonyloxy optionally substituted by halogen, alkylsulfonyloxyalkoxy, amino, alkanoylamino, benzoylamino, alkenyloxy, phenylalkoxyalkoxy, hydroxyalkoxy, phenylalkoxy having optionally 1 to 3 substituents selected from halogen, alkyl and alkoxy, halogenoalkyl, cycloalkyloxy optionally substituted by hydroxy, alkoxy substituted by cycloalkyl having optionally hydroxy substituent, imidazolylalkyl or imidazolylalkoxy; k is 0 or 1 to 3; or (R 1 ) k is alkylenedioxy; A is alkylene or alkylenoxy; l is 0 or 1; B is methylene or carbonyl; m is 0 or 1; D is alkylene; E is alkylene or alkenylene; n is 0 or 1; and R 2 is hydrogen or alkyl, or a salt thereof, which have fatty acid synthesis-inhibitory activity, cholesterol synthesis-inhibitory activity and are useful as antilipidemic agent, prophylactic and treating agent of arteriosclerosis, prophylactic and treating agent of obesity, antidiabetics.

专利号:CN-114369248-B
优先权日:2020-10-15
标题 :A kind of chiral silicon-containing polyester and its synthesis method