CAS: 177756-62-6; 3-Fluoro-4-Methylbenzaldehyde

上下游产品

CAS号104-87-0 对甲基苯甲醛 | CAS号95-52-3 邻氟甲苯 | CAS号201230-82-2 carbon monoxide | CAS号350-28-7 3-氟-4-甲基苯甲酸 | CAS号192702-79-7 3-氟-4-甲基苯甲醇 | CAS号261951-67-1 3-氟-4-甲基苄胺 | CAS号170572-49-3 3-氟-4-甲基苯甲腈 | CAS号503824-88-2 Benzenemethanol...

对甲基苯甲醛置于硫酸,Fluorine体系中,化学反应 1.75H,以60%的收率获得3-氟-4-甲基苯甲醛
参考文献:元素氟第12部分.1,4-二取代芳族化合物的氟化
标题:元素氟第12部分.1,4-二取代芳族化合物的氟化
摘要:在酸性反应介质中,在方便的温度下,将一系列的1,4-二取代的苯衍生物进行直接氟化,在许多情况下,会以制备上有用的转化率和收率选择性地氟化芳族产物.
Doi:10.1016/s0022-1139(99)00238-9

专利信息

专利号:US-9701686-B2
优先权日:2009-12-04
标题:Tricyclopyrazole derivatives
发明人：DISINGRINI TERESA; MANTEGANI SERGIO; VARASI MARIO
权利人:NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are tricyclopyrazole derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.