CAS: 14365-44-7; (2R,3R,4S,5R)-2-(6-Amino-9H-Purin-9-yl)-5-(Aminomethyl)Tetrahydrofuran-3,4-Diol

相似化合物

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上下游产品

CAS号737-76-8 Adenosine,5'-az... | CAS号57610-04-5 N6-benzoyl-5'-a... | CAS号68144-26-3 5'-azido-5'-deo... | CAS号4546-55-8 N6-苯甲酰基腺苷 | CAS号362-75-4 2',3'-异丙叉腺苷 | CAS号80860-44-2 2-(((3aR,4R,6R,... | CAS号21950-36-7 5'-氨基-5'-脱氧-2',...

📜N6-Benzoyl-2',3'-O-Isopropylidene-5'-O-Methylsulfonyladenosine置于lindlar'S Catalyst Sodium Azide,氢气,Sodium Methylate,三氟乙酸体系中,用 甲醇,N,N-二甲基甲酰胺 用作溶剂,化学反应 28.25H,反应生成5-氨基腺苷酸
参考文献:Design,Synthesis,And Molecular Modeling Studies Of 5'-Deoxy-5'-Ureidoadenosine: 5'-Ureido Group As Multiple Hydrogen Bonding Donor In The Active Site Of S-Adenosylhomocysteine Hydrolase
标题:Design,Synthesis,And Molecular Modeling Studies Of 5'-Deoxy-5'-Ureidoadenosine: 5'-Ureido Group As Multiple Hydrogen Bonding Donor In The Active Site Of S-Adenosylhomocysteine Hydrolase
摘要:5'-Deoxy-5'-Ureidoadenosine Was Designed And Synthesized As A Potent Inhibitor Of S-Adenosylhomocysteine Hydrolase (Sah),In Which 5'-Ureido Group Acted As Multiple Hydrogen Bonding Donor In Binding With Active Site Residues Of Sah In The Molecular Modeling Study. (C) 2007 Published By Elsevier Ltd.
Doi:10.1016/j.Bmcl.2007.06.013

专利信息

专利号:US-2003134303-A1
优先权日:2001-12-11
标 题:Adenine nucleotide-binding protein-directed probes, and methods of their synthesis and use
发明人：CAMPBELL DAVID A; WASH PAUL
权利人:ACTIVX BIOSCIENCES INC
摘要:The invention relates to compositions and methods for the synthesis and use of Adenosine nucleotide binding protein-directed affinity labels. Adenosine nucleotide binding proteins may be labeled with probes comprising adenosine, or an analogue thereof, functionalized at the 5′ position with reactive group capable of reacting with an amino acid side chain functionality at an adenosine nucleotide binding site, and at the 2′ or 3′ position with a TAG for sequestering and/or identifying the resulting conjugate. The probes may be used for determining the presence or amount of one or more adenosine nucleotide binding proteins in a complex mixture, particularly a cellular mixture, for screening for drugs, and other purposes associated with the presence of the adenine nucleotide-binding protein(s) in a cell or changes in the presence, amount, activity, or relative concentration of the active adenosine nucleotide-binding protein.

专利号:US-7999087-B2
优先权日:2006-11-15
标 题:2′-silyl containing thiocarbonate protecting groups for RNA synthesis
发明人：DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA; CARUTHERS MARVIN H; DELLINGER GERALDINE F
权利人:AGILENT TECHNOLOGIES INC
摘要:Nucleoside monomers, nucleic acids, e.g., oligonucleotides and polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein. Aspects of the invention include 2′ silyl containing thiocarbonate protecting groups. Corresponding compositions and methods are provided.

专利号:US-9067961-B2
优先权日:2007-05-10
标 题 :Thiocarbon-protecting groups for RNA synthesis
发明人：DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA B; TURNER JOHN; MYERSON JOEL; KUPIHAR ZOLTAN; FERREIRA FERNANDO; CARUTHERS MARVIN H; DELLINGER GERALDINE F
权利人:DELLINGER DOUGLAS J; SIERZCHALA AGNIESZKA B; TURNER JOHN; MYERSON JOEL; KUPIHAR ZOLTAN; FERREIRA FERNANDO; CARUTHERS MARVIN H; DELLINGER GERALDINE F; AGILENT TECHNOLOGIES INC; UNIV COLORADO DENVER
摘要:Aspects of the invention include 2′ protected nucleoside monomers that are protected at the 2′ site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.

专利号:EP-1578931-A4
优先权日:2002-07-16
标 题:METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE THE SYNTHESIS OF IL-4 RECEPTOR-MEDIATED IGE USING ADENOSINE KINASE

专利号:WO-2004007680-A2
优先权日:2002-07-16
标题:Methods of identifying compounds that modulate il-4 receptor-mediated ige synthesis utilizing an adenosine kinase

专利号:WO-03050248-A2
优先权日:2001-12-11
标 题:Adenine nucleotide-binding protein-directed probes and methods of their synthesis and use