CAS: 109-29-5; 16-Hexadecanolide

该化合物是化学配方C16H30O2的圆形酯,其特点是长碳链,其特性是长碳链,它有助于其蜡质质质和疏水特性.该化合物一般是无色的黄色液体或固体,视温度而定.Hexadecanolide以其令人愉快,脂肪味闻而闻名,使其在香味工业中有用.它也用于制造各种化妆品产品,因为其化学特性.该物质在正常条件下相对稳定,但在有强酸或碱的情况下可能进行水解,其溶解作用限于水中,但在乙醇和乙醇等有机溶剂中可溶解.Hexadecanolide没有被归类为危险物质,但在处理该物质时应注意标准的安全防范措施.

结构式图片

欧盟法规

欧盟化妆品法规附录三-限用物质清单REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号506-13-8 16-羟基十六烷酸 | CAS号2536-36-9 ihda | CAS号28645-51-4 (Z)-氧代环十七碳-8-烯-2-酮 | CAS号2536-35-8 16-溴十六烷酸 | CAS号2550-52-9 环十二酮 | CAS号85258-69-1 ethyl 16-hydrox... | CAS号67-63-0 异丙醇 | CAS号85115-85-1 potassium salt ... | CAS号107223-88-1 oxacycloheptade... | CAS号506-13-8 16-羟基十六烷酸 | CAS号1220909-16-9 N-oleyl-16-hydr... | CAS号2536-36-9 ihda | CAS号59101-28-9 16-溴-1-十六烷醇 | CAS号7735-42-4 1,16-十六烷二醇 | CAS号2536-35-8 16-溴十六烷酸 | CAS号36575-67-4 methyl 16-hydro... | CAS号26825-89-8 16-溴十六烷酸甲酯 | CAS号824404-34-4 19-[tert-butyl(...

合成工艺路线路线简述

  • 合成目标产物 16-Hexadecanolide 主要起始原料 Ambrettolide
  • (文献来源)合成步骤主要原料 Ambrettolide
📜15-Hexadecenoic Acid置于氢溴酸,Potassium Carbonate,丁酮,Petroleum Ether,过氧化苯甲酰体系中,化学反应生成氧杂环十七烷-2-酮
参考文献:Plesek,Collection Of Czechoslovak Chemical Communications,1957,Vol. 22,P. 49,51
标题:Plesek,Collection Of Czechoslovak Chemical Communications,1957,Vol. 22,P. 49,51

海关参考信息

专利信息


专利号:US-5981240-A
优先权日:1996-11-27
标题:Enzyme-catalyzed synthesis of macromolecules in organic solvents
发明人:AKKARA JOSEPH A; BRUNO FERDINANDO F
权利人:US ARMY
摘要:A method is described for a simple, fast and efficient synthesis of homopolymers and copolymers by the enzymatic ring opening polymerization of lactones and lactides. The enzyme used is an ion paired protease. The advantage of this enzymatic system is in using small amount of enzyme per monomer and lower reaction time. Homopolymers and copolymers are synthesized with molecular weights between 1000 and 4600 daltons, and dispersity as low as 1.1. The monomer conversion after 4 days, for reactions catalyzed by protease S, has reached 100%. Different initiators are used to control the rate and degree of polymerization. Synthesis of block copolymers with defined block size and crystallinity are described in this invention. These biodegradable and bioerodable polyesters and copolyesters with controlled molecular weight, dispersity and crystallinity have applications in medical, drug, cosmetic and food industries.

专利号:US-7893286-B2
优先权日:2007-06-01
标题 :Method for the synthesis of phospholipid ethers
发明人:PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
权利人:CELLECTAR INC
摘要:Disclosed are improved methods for the synthesis of phospholipid ether analogs and alkyl phosphocholine analogs. The methods allow greater versatility of the reactants used and greater ease in synthesizing alkyl chains of varying length while affording reaction temperatures at room temperature or below. The methods disclosed herein provide reactants and conditions using alkyl halides and organozinc reagents and do not utilize Gringard reactions thus, allowing greater ease of their separation and purity of products. The PLE compounds synthesized by the methods disclosed herein can also be used for synthesizing high specific activity phospholipid ether (PLE) analogs, for use in treatment and diagnosis of cancer.

专利号:US-5502226-A
优先权日:1994-11-14
标 题:Process of preparing ω-hydroxy acids
发明人:CHO SUK H; DEFLORIO VICTOR
权利人:ARDEN ELIZABETH CO
摘要:A new synthesis of omega -hydroxy acids, which employs commercially available starting materials and lowers the cost of production. The process involves coupling a fatty acyl group by enamine chemistry, followed by a ring expansion and selective reduction of ketoacid.

专利号:US-9567430-B2
优先权日:2011-12-02
标 题 :Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
发明人:SALTZMAN W MARK; JIANG ZHAOZHONG; ZHOU JIANGBING; LIU JIE
权利人:UNIV YALE
摘要:Poly(amine-co-ester) polymers, methods of forming active agent-load nanoparticles therefrom, and methods of using the nanoparticles for drug delivery are disclosed. The nanoparticles can be coated with an agent that reduces surface charge, an agent that increases cell-specific targeting, or a combination thereof. Typically, the loaded nanoparticles are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the nanoparticles are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition.

专利号:WO-2013082529-A1
优先权日:2011-12-02
标题 :Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
发明人:SALTZMAN W MARK; JIANG ZHAOZHONG; ZHOU JIANGBING
权利人:UNIV YALE
摘要:Poly(amine-co-ester) polymers, methods of forming active agent-load nanoparticies therefrom, and methods of using the nanoparticies for drug delivery are disclosed. The nanoparticies can be coated with an agent that reduces surface charge, an agent that increases cell-specific targeting, or a combination thereof. Typically, the loaded nanoparticies are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the nanoparticies are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition.

专利号:US-8022235-B2
优先权日:2007-06-01
标 题 :Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use
发明人:PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
权利人:CELLECTAR INC
摘要:The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1007/b14130
摘要:Food and Cosmetics Toxicology., 13(452), 1975
摘要:Maier, M. E., Science of Synthesis, (2007) 20, 1465.
摘要:Maier, M. E., Science of Synthesis, (2007) 20, 1456.
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