Silver;Tris(4-Methylphenyl)Phosphane;Nitrate 以 水,乙腈 用作溶剂,化学反应生成三对苯甲基膦 参考文献:Solution Structure And Kinetic Study Of Metal-Phosphine And-Phosphite Complexes. I. Silver (I) System 标题:Solution Structure And Kinetic Study Of Metal-Phosphine And-Phosphite Complexes. I. Silver (I) System 摘要: Doi:10.1021/ja00773A022
专利信息
专利号:US-10889599-B2 优先权日:2018-02-27 标 题:1,1-diborylalkyl-1-metal compounds, preparation method thereof, and their applications toward synthesis of 1,1-diboronate ester compounds 发明人:CHO SEUNG HWAN; LEE YEOSAN 权利人:POSTECH ACAD IND FOUND 摘要:The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.
专利号:US-8642809-B2 优先权日:2007-09-25 标 题:Methods of synthesis of certain hydroxamic acid compounds 发明人:REISCH HELGE A; LEEMING PETER; RAJE PRASAD S 权利人:REISCH HELGE A; LEEMING PETER; RAJE PRASAD S; TOPOTARGET UK LTD 摘要:The present invention pertains to the general field of chemical synthesis, and more particularly to methods for the synthesis of certain hydroxamic acid compounds, and in particular, (E)-N-hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamide, also known as PXD101 and Belinostat®, comprising, for example, the steps of: (SAF) sulfonamide formation; (PUR C ) optional purification; (AAA) alkenyl-acid addition, comprising: either (i): the steps of, in order: (ACAEA) alkenyl-carboxylic acid ester addition; (PUR E ) optional purification; and (CAD) carboxylic acid deprotection; or (ii): the step of: (ACAA) alkenyl-carboxylic acid addition; (PUR F ) optional purification; (HAF) hydroxamic acid formation; and (PUR G ) optional purification.
专利号:US-4794199-A 优先权日:1984-07-05 标题:Process for synthesis of primary amines from olefins, syngas and ammonia 发明人:LIN JIANG-JEN; KNIFTON JOHN F 权利人:TEXACO INC 摘要:This invention concerns the synthesis of primary amines from olefins, synthesis gas and ammonia via an amination process in the presence of a cobalt catalyst, an ether solvent and a tertiary group VB donor ligand.
专利号:US-2023286918-A1 优先权日:2020-07-02 标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat 发明人:JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER 权利人:AKEBIA THERAPEUTICS INC 摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.
专利号:US-2022298136-A1 优先权日:2019-08-21 标题 :Process for synthesis of pyrazolidinone compounds 发明人:MATHUR SUCHET SARAN; JAIN NANDKUMAR JANARDAN; MORE MAHENDRA MAHIPAT 权利人:GHARDA CHEMICALS LTD 摘要:A process for the synthesis of pyrazolidinone, particularly alkyl 2-(3-chloropyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylate (pyrazolidinone) compound, is provided. The process is simple, economical, and produces alkyl 2-(3-chloropyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylate with a comparatively high yields.
专利号:WO-2021033165-A1 优先权日:2019-08-21 标 题:Process for synthesis of pyrazolidinone compounds 发明人:MATHUR SUCHET SARAN; MHATRE HRIDAYNATH VISHWANATH; PEDHAVI VISHAL PARSHURAM 权利人:GHARDA CHEMICALS LTD 摘要:The present disclosure relates to a process for the synthesis of pyrazolidinone, particularly alkyl 2-(3-chloropyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylate (pyrazolidinone) compound. The process of the present disclosure is simple, economical, and produces alkyl 2-(3-5 chloropyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylate with a comparatively high yields.
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