CAS: 10344-93-1; Acrylate

📜丙烯酰胺,水 反应生成丙-2-烯酸酯,铵
参考文献:The Amie Aliphatic Amidase And Amif Formamidase Of Helicobacter Pylori: Natural Evolution Of Two Enzyme Paralogues
标题:The Amie Aliphatic Amidase And Amif Formamidase Of Helicobacter Pylori: Natural Evolution Of Two Enzyme Paralogues
摘要:Aliphatic Amidases (Ec 3.5.1.4) Are Enzymes Catalysing The Hydrolysis Of Short‐chain Amides To Produce Ammonia And The Corresponding Organic Acid. Such An Amidase,Amie,Has Been Detected Previously In Helicobacter Pylori. Analysis Of The Complete H. Pylori Genome Sequence Revealed The Existence Of A Duplicated Amidase Gene That We Named Amif. The Corresponding Amif Protein Is 34% Identical To Its Amie Paralogue. Because Gene Duplication Is Widely Considered To Be A Fundamental Process In The Acquisition Of Novel Enzymatic Functions,We Decided To Study And Compare The Functions Of The Paralogous Amidases Of H. Pylori. Amie And Amif Proteins Were Overproduced In Escherichia Coli And Purified By A Two‐step Chromatographic Procedure. The Two H. Pylori Amidases Could Be Distinguished By Different Biochemical Characteristics Such As Optimum Ph Or Temperature. Amie Hydrolysed Propionamide,Acetamide And Acrylamide And Had No Activity With Formamide. Amif Presented An Unexpected Substrate Specificity: It Only Hydrolysed Formamide. Amif Is Thus The First Formamidase (Ec 3.5.1.49) Related To Aliphatic Amidases To Be Described. Cys‐165 In Amie And Cys‐166 In Amif Were Identified As Residues Essential For Catalysis Of The Corresponding Enzymes. H. Pylori Strains Carrying Single And Double Mutations Of Amie And Amif Were Constructed. The Substrate Specificities Of These Enzymes Were Confirmed In H. Pylori. Production Of Amie And Amif Proteins Is Dependent On The Activity Of Other Enzymes Involved In The Nitrogen Metabolism Of H. Pylori (Urease And Arginase Respectively). Our Results Strongly Suggest That (I) The H. Pylori Paralogous Amidases Have Evolved To Achieve Enzymatic Specialization After Ancestral Gene Duplication; And (II) The Production Of These Enzymes Is Regulated To Maintain Intracellular Nitrogen Balance In H. Pylori.
Doi:10.1046/j.1365-2958.2001.02400.X

专利信息

专利号:US-6794534-B2
优先权日:2000-06-23
标题:Synthesis of functionalized and unfunctionalized olefins via cross and ring-closing metathesis
发明人：GRUBBS ROBERT H; CHATTERJEE ARNAB K; MORGAN JOHN P; SCHOLL MATTHIAS; CHOI TAE-LIM
权利人:CALIFORNIA INST OF TECHN
摘要:The invention is directed to the cross-metathesis and ring-closing metathesis reactions between geminal disubstituted olefins and terminal olefins, wherein the reaction employs a Ruthenium or Osmium metal carbene complex. Specifically, the invention relates to the synthesis of α-functionalized or unfunctionalized olefins via intermolecular cross-metathesis and intramolecular ring-closing metathesis using a ruthenium alkylidene complex. The catalysts preferably used in the invention are of the general formula n wherein: n M is ruthenium or osmium; n X and X 1 are each independently an anionic ligand; n L is a neutral electron donor ligand; and, n R, R 1 R 6 , R 7 , R 8 , and R 9 are each independently hydrogen or a substituent selected from the group consisting of C 1 -C 20 alkyl, C 2 -C 20 alkenyl, C 2 -C 20 alkynyl, aryl, C 1 -C 20 carboxylate, C 1 -C 20 alkoxy, C 2 -C 20 alkenyloxy, C 2 -C 20 alkynyloxy, aryloxy, C 2 -C 20 alkoxycarbonyl, C 1 -C 20 alkylthio, C 1 -C 20 alkylsulfonyl and C 1 -C 20 alkylsulfinyl.

专利号:US-6515039-B1
优先权日:1998-08-28
标 题:Method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material
发明人：ULBRICHT MATHIAS; VOLKMER-ENGERT RUDOLF; GERMEROTH LOTHAR; WENSCHUH HOLGER
权利人:POLY AN GMBH
摘要:The invention relates to a method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material. According to the method, a continuous polymeric solid phase supporting material is prepared, the material comprising a matrix of a supporting polymeric material and graft copolymer chains covalently bound to the supporting matrix, the graft copolymer chains having reactive groups being able to react with organic compounds, thereby forming spatially defined reaction sites. The method then comprises the sequential spotting of synthesis building blocks or reagents at the various reaction sites on the continuous solid phase supporting material to yield a substrate library of compounds bound to the solid phase supporting material, whereby each reaction site on the continuous solid phase supporting material determines the composition of the synthesized compound, which is bound directly on the supporting matrix via the reactive groups of the graft polymer chain.

专利号:US-4720573-A
优先权日:1986-07-31
标 题:Process for synthesis of glutamic acid from acrylate, amide and synthesis gas
发明人：LIN JIANG-JEN
权利人:TEXACO INC
摘要:A process for the synthesis of glutamic acid intermediate from an acrylate, amide and syngas by reacting them in the presence of a catalyst comprising a cobalt-containing compound, a bis-phosphine ligand and a solvent at a pressure of at least 500 psi and a temperature of at least 50° C. and thereafter extracting the glutamic acid.

专利号:US-2021130543-A1
优先权日:2019-10-30
标 题:Synthesis of cyanurate and multifunctional alcohol-based polyether acrylate for uv curable materials
发明人：YUAN ZHONGSHUN; XU CHUNBAO; WU WEI
权利人:YUAN ZHONGSHUN; XU CHUNBAO; WU WEI
摘要:Polyether (meth)acrylates based on cyanuric acid or substituted cyanuric acid and multifunctional alcohol, which optionally include triethanolamine units, have wide applications in UV curable adhesives, coatings, inks, sealants, paints or 3D printing. These polyether acrylates have rigid cyanurate structure endowing the material with extra strength and thermal stability. Furthermore, triethanolamine unit, when present, endows the material with anti-oxygen inhibition property in UV curing process. These polyether (meth)acrylates have low viscosity and high reactivity towards UV curing. The cured resins have high resilience and strength. The process of making the polyether (meth)acrylates includes the synthesis of trifunctional polyether polyols through controlled polymerization of propylene oxide using multifunctional alcohol (such as glycerol and sucrose), cyanuric acid or substituted cyanuric acid, and optionally triethanolamine, in the presence of a catalyst, followed by the synthesis of polyether (meth)acrylates through transesterification or through direct esterification of the trifunctional polyether polyols.

专利号:US-6512081-B1
优先权日:1997-07-21
标题:Synthesis of dithioester chain transfer agents and use of bis(thioacyl) disulfides or dithioesters as chain transfer agents
发明人：RIZZARDO ENZIO; THANG SAN HOA; MOAD GRAEME
权利人:E I DUPONT NEMOURS AND COMPANY; COMMW SCIENT IND RES ORG
摘要:This invention relates to the synthesis of dithiocarboxylic acid esters by reaction of bis(thioacyl) disulphides, thioacetals or vinylidane bis(thioether) with free-radicals (optionally in the presence of monomers). The invention also relates to processes for the synthesis of polymers utilising these dithioesters as polymerisation regulators (chain transfer agents) or to the use of bis(thioacyl) disulphides to generate dithioester chain transfer agents in situ.

专利号:US-2012184653-A1
优先权日:2011-01-18
标 题:Synthesis of linear phosphorus-containing functional fluorocopolymer
发明人：WANG LIANG; WANG VIKTORIA
权利人:WANG LIANG; WANG VIKTORIA
摘要:This invention relates to a synthesis of a linear fluorocopolymer having a plurality of pendant phosphorus-containing functional groups. The synthesized phosphorus-containing fluorocopolymer has chain linearity and narrow molecular weight distributions. It has applications as a lubricant additive that provides friction-reduction, anti-wear, and corrosion protection properties.