CAS: 95734-82-0; (Sp-4-3)-Diammine[2-(Hydroxy-?O)Acetato(2-)-?O]Platinum

上下游产品

CAS号41575-87-5 cis-Diamminedin... | CAS号25289-18-3 sodium glycollate | CAS号79-14-1 羟基乙酸 | CAS号63700-88-9 {Pt[a2](OH)2}

羟基乙酸,顺式-二氨基二硝酸基铂 以 水 作为反应溶剂,以43%的收率获得产物奈达铂
参考文献:Synthesis Of (Glycolato-O,O')Diammineplatinum(II) And Its Related Complexes
标题:Synthesis Of (Glycolato-O,O')Diammineplatinum(II) And Its Related Complexes
摘要:甘醇酸合铂(II)配合物[pt(ococh2O)L2]是一种具有新型五元环结构的化合物,通过将甘醇酸与水合顺式-[pt(Oh)2L2](l:Nh3,胺)等摩尔比混合并在水中加热制得.这些配合物也可通过顺式-[pt(No3)2L2]与甘醇酸钠在中性水溶液中反应反应生成.通过二次离子质谱,红外光谱和核磁共振波谱技术对这些配合物进行了表征.
DOI:10.1246/cl.1986.429

专利信息

专利号:US-8734846-B2
优先权日:2008-06-16
标 题 :Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles
发明人：ALI MIR M; HRKACH JEFF; ZALE STEPHEN E; ALVAREZ DE CIENFUEGOS LUIS
权利人:BIND BIOSCIENCES INC
摘要:This application provides nanoparticles and methods of making nanoparticles using pre-functionalized poly(ethylene glycol)(also referred to as PEG) as a macroinitiator for the synthesis of diblock copolymers. Ring opening polymerization yields the desired poly(ester)-poly (ethylene glycol)-targeting agent polymer that is used to impart targeting capability to therapeutic nanoparticles. This “polymerization fromâ€? approach typically employs precursors of the targeting agent wherein the reactivity of functional groups of the targeting agent is masked using protecting groups. Also described is a “coupling toâ€? that utilized the poly(ethylene glycol)-targeting agent conjugate where the targeting agent remains in its native un-protected form. This method uses “orthogonalâ€? chemistry that exhibit no cross reactivity towards functional groups typically found within targeting agents of interest.

专利号:TR-201815941-A2
优先权日:2018-10-25
标 题 :Synthesis of a new benzimidazolium salt with high anticancer effect in breast cancer treatment

专利号:US-8470965-B2
优先权日:2006-03-01
标题 :Methods and compositions related to cyclic peptide synthesis
发明人：SCHMIDT ERIC W; HATHAWAY BRIAN; NELSON JAMES T; DONIA MOHAMED S
权利人:SCHMIDT ERIC W; HATHAWAY BRIAN; NELSON JAMES T; DONIA MOHAMED S; UNIV UTAH RES FOUND
摘要:Disclosed are compositions and methods for prenylation of polymers such as peptides.

专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof

专利号:BR-102016028580-B1
优先权日:2016-12-06
标题 :SYNTHESIS AND APPLICATION OF MONONUCLEAR PLATINUM(II) COMPOUNDS AS CYTOTOXIC AGENTS MIMETIC TO CIS-PLATINUM

专利号:BR-102016028580-A2
优先权日:2016-12-06
标题:SYNTHESIS AND APPLICATION OF MONONUCLEAR PLATIN COMPOUNDS (II) AS CIM-PLATIN MIME CYTOTOXIC AGENTS