CAS: 7031-27-8; (Phenylthio)Acetyl Chloride

上下游产品

(phenylthio)acetic acid ethyl phenylsulfenylacetate thiophenol chloroacetyl chloride S)-1-methyl-2-phenyl-ethylamide)phenylsulfanyl-acetic acid-((S)-1-methyl-2-phenyl-ethylamide) t,5c-trimethyl-4-phenyl-[4r]piperidyl ester)(+/-)-phenylsulfanyl-acetic acid-(1,2t,5c-trimethyl-4-phenyl-[4r]piperidyl ester) 1-diazo-3-phenylthiopropan-2-one 1-chloro-3-phenylsulfanylpropan-2-one

📜苯硫基乙酸置于氯化亚砜,N,N-二甲基甲酰胺体系中,化学反应 12.0H,反应生成 (苯基硫醇)乙酰氯
参考文献:扭曲的半硫靛光开关:溶剂极性决定光致旋转的类型
标题:扭曲的半硫靛光开关:溶剂极性决定光致旋转的类型
摘要:通过外部刺激控制分子的内部运动是产生响应性和复杂的分子行为和功能的决定性任务.由于信号应用的简便性和高可重复性,光致开关的光致结构变化特别受到关注.通常,光开关在其切换过程中使用一个反应坐标,并在两个或多或少定义的状态之间变化.在这里,我们报告了新的扭曲半硫靛光开关,使两种不同的反应坐标可用于切换过程.根据溶剂的极性,可见光可以诱导完全单键(在 Dmso 中)或双键(在环己烷中)旋转.这种相互独立的开关在此类光开关中建立了前所未有的分子内旋转二维控制.机械解释涉及在激发态形成高度极性扭曲的分子内电荷转移物质,并基于大量实验量化,最显着的是在不同极性溶剂中的超快光谱和量子产率测量.在基态预扭曲以在激发态打开新的独立反应坐标的概念应该可以转移到其他光开关系统.最显着的是在不同极性溶剂中的超快光谱和量子产率测量.在基态预扭曲以在激发态打开新的独立反应坐标的概念应该可以转移到其他光开关系统.最显着
DOI:10.1021/jacs.6B05981

专利信息

专利号:US-7202370-B2
优先权日:2003-10-27
标 题 :Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
发明人：NAIDU RAGINA
权利人:CONOR MEDSYSTEMS INC
摘要:A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably protected baccatin III backbone from 9-dihydro-13-acetylbaccatin III, and the insertion of the phenylisoserine side chain onto the protected baccatin III from 9-dihydro-13-acetylbaccatin III to form the taxane derivatives, paclitaxel and docetaxel is disclosed.

专利号:US-2003004337-A1
优先权日:2000-05-04
标 题 :Efficient lactam synthesis
发明人：JUNG KYUNG WOON; YOON CHEOL HWAN
摘要:Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a γ-lactam, in which an a-diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C-H insertion, for example in the presence of a rhodium salt such as Rh 2 (OAc) 4 , n n n by which means lactams that are precursors in the synthesis of diverse natural and synthetic products, including pyrrolidinone compounds such as lactacystin, pramanicin, kainic acid, statine, AHPPA, and rolipram, are produced.

专利号:US-6689890-B2
优先权日:2000-05-04
标 题:Efficient lactam synthesis
发明人：JUNG KYUNG WOON; YOON CHEOL HWAN
权利人:UNIV SOUTH FLORIDA
摘要:Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a gamma-lactam, in which an alpha-diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C-H insertion, for example in the presence of a rhodium salt such as Rh2(OAc)4,by which means lactams that are precursors in the synthesis of diverse natural and synthetic products, including pyrrolidinone compounds such as lactacystin, pramanicin, kainic acid, statine, AHPPA, and rolipram, are produced.

专利号:US-4536334-A
优先权日:1979-06-28
标题 :Preparation of β-lactam derivatives
发明人：SUNAGAWA MAKOTO; MATSUMURA HARUKI; INOUE TAKAAKI; HIROHASHI TOSHIYUKI
权利人:SUMITOMO CHEMICAL CO
摘要:A process for preparing a β-lactam derivative having a hydrogen atom on the nitrogen atom of the β-lactam ring, which comprises reacting a β-lactam derivative having a mono- or diarylmethyl group on the nitrogen atom of the β-lactam ring with an acid or ceric ammonium nitrate to cleave the bond between the nitrogen atom and the mono- or diarylmethyl group; and novel β-lactam derivatives useful as intermediates for the synthesis of pharmaceutical agents.

专利号:US-4734495-A
优先权日:1985-07-17
标 题 :Process and intermediates for beta-lactam antibiotics
发明人：EVANS DAVID A; SJOGREN ERIC B
权利人:HARVARD COLLEGE
摘要:1-Benzyl(or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##