📜2,3-二甲基-1-丁烯置于aluminium Oxide-Chromium Oxide,二氧化硫体系中,化学反应生成 3,4-二甲基噻吩 参考文献:Jurew; Chmelnizkii,Doklady Akademii Nauk Sssr,1953,Vol. 92,P. 101,103 标题:Jurew; Chmelnizkii,Doklady Akademii Nauk Sssr,1953,Vol. 92,P. 101,103
专利信息
专利号:US-9802952-B2 优先权日:2013-07-15 标 题:Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives 发明人:KOPETZKI DANIEL; MCQUADE DAVID TYLER; SEEBERGER PETER H; GILMORE KERRY 权利人:MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V; MAX-PLANK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V 摘要:The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C 1 -C 5 alcohol.
专利号:US-8106031-B2 优先权日:2006-05-02 标题:Hydrolytically-resistant boron-containing therapeutics and methods of use 发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A 权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC 摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
专利号:WO-2007007735-A1 优先权日:2005-07-12 标 题 :Synthesis of organic conductive polymerizable material onto metal oxide surface through light irradiation 发明人:TACHIBANA YASUHIRO 权利人:UNIV OSAKA; KANSAI TECH LICENSING ORG CO; TACHIBANA YASUHIRO 摘要:Disclosed is a composite material having a nanostructure containing metal oxide fine particles and an organic conductive polymerizable material. In this composite material, the metal oxide fine particles are joined with one another and the organic conductive polymerizable material is contained in the spaces between the fine particles. In this connection, the organic conductive polymerizable material is a copolymer which is composed of a polythiophene derivative, a thiophene or a derivative thereof and pyrrole, aniline, fluorene, furan or a derivative thereof. Also disclosed is a method for producing such a composite material. This composite material is useful for display elements such as electronic paper.
专利号:US-2429575-A 优先权日:1944-09-16 标 题:Synthesis of branched chain hydrocarbons 发明人:APPLEBY WALTER G; LOVELL LAWRENCE L; LOVE MARK P L 权利人:SHELL DEV
专利号:US-8598166-B2 优先权日:2008-03-21 标 题:Polysubstituted derivatives of 6-heteroarylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof 发明人:DE PERETTI DANIELLE; EVANNO YANNICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE 权利人:DE PERETTI DANIELLE; EVANNO YANNICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; SANOFI SA 摘要:Compounds of formula (I): n nwherein R 1 , R 2 , R 3 , R 4 , Het and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.
专利号:US-8338451-B2 优先权日:2008-03-21 标 题 :Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof 发明人:DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO 权利人:DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO; SANOFI SA 摘要:Compounds of formula (I): n nwherein R, R 1 , R 2 , R 3 , R 4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.
参考标题:Metal-Free Oxidative Coupling Reactions Via σ-Iodonium Intermediates: The Efficient Synthesis Of Bithiophenes Using Hypervalent Iodine Reagents 作者:Koji Morimoto,Tomofumi Nakae,Nobutaka Yamaoka,Toshifumi Dohi,Yasuyuki Kita |发布日期:2011.11 摘要:The Direct Oxidative Biaryl Coupling Reaction Is An Attractive Tool For Environmentally Benign Green Chemistry. A Novel Direct Method For The Synthesis Of Bithiophene Using A Hypervalent Iodine Reagent Has Been Developed. The Reaction Mechanism Has Also Been Investigated, Casting Light On The Reaction Intermediate And Revealing The Reactivity With Iodonium Salts.
合成参考文献
摘要:Sambiagio, C.; Maes, B. U. W., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 144.