CAS: 632-15-5; 3,4-Dimethylthiophene

该化合物是有机化合物,其特点是五人组成的芳香环结构,包括硫磺原子和附属于硫苯环3和4位置的两个甲基组.其分子式为C6H8S,表明存在六个碳原子,八个氢原子和一个硫原子.该化合物一般是无色的,可粉色黄色液体,有独特的气味,经常被称为某些种类自然产品的甜味和某种微小的微粒.3,4-二甲基硫苯因其在有机合成中的作用和在生产各种化学品(包括制药和农用化学品)中的中间作用而闻名.该物质在水中表现出中等溶性,但在有机溶剂中更溶性.该混合物在正常条件下稳定,但可能会发生典型的硫苯反应,例如电药替代.安全数据表明,应当谨慎处理,因为它可能会刺激皮肤和眼睛.

结构式图片

上下游产品

CAS号513-81-5 2,3-二甲基-1,3-丁二烯 | CAS号19799-13-4 3,4-Dimethyl-2,... | CAS号3141-26-2 3,4-二溴噻吩 | CAS号917-64-6 甲基碘化镁 | CAS号23838-22-4 (Z,Z)-Bis(1-pro... | CAS号23838-23-5 trans,trans-dip... | CAS号30318-99-1 3-溴-4-甲基噻吩 | CAS号77-78-1 硫酸二甲酯 | CAS号121609-82-3 (E)-1-propenyl ... | CAS号1795-04-6 2,3,5-三甲基噻吩 | CAS号89639-74-7 3,4-二甲基噻吩-2-甲酸 | CAS号188290-36-0 Thiophene(SIV) | CAS号554-14-3 2-甲基噻吩 | CAS号638-00-6 2,4-二甲基噻吩 | CAS号108-88-3 甲苯 | CAS号632-16-6 2,3-二甲基噻吩 | CAS号638-02-8 2,5-二甲基噻吩 | CAS号616-44-4 3-甲基噻吩 | CAS号71-43-2 苯

合成工艺路线路线简述

    📜2,3-二甲基-1-丁烯置于aluminium Oxide-Chromium Oxide,二氧化硫体系中,化学反应生成 3,4-二甲基噻吩
    参考文献:Jurew; Chmelnizkii,Doklady Akademii Nauk Sssr,1953,Vol. 92,P. 101,103
    标题:Jurew; Chmelnizkii,Doklady Akademii Nauk Sssr,1953,Vol. 92,P. 101,103

    专利信息


    专利号:US-9802952-B2
    优先权日:2013-07-15
    标 题:Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives
    发明人:KOPETZKI DANIEL; MCQUADE DAVID TYLER; SEEBERGER PETER H; GILMORE KERRY
    权利人:MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V; MAX-PLANK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V
    摘要:The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C 1 -C 5 alcohol.

    专利号:US-8106031-B2
    优先权日:2006-05-02
    标题:Hydrolytically-resistant boron-containing therapeutics and methods of use
    发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
    权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC
    摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

    专利号:WO-2007007735-A1
    优先权日:2005-07-12
    标 题 :Synthesis of organic conductive polymerizable material onto metal oxide surface through light irradiation
    发明人:TACHIBANA YASUHIRO
    权利人:UNIV OSAKA; KANSAI TECH LICENSING ORG CO; TACHIBANA YASUHIRO
    摘要:Disclosed is a composite material having a nanostructure containing metal oxide fine particles and an organic conductive polymerizable material. In this composite material, the metal oxide fine particles are joined with one another and the organic conductive polymerizable material is contained in the spaces between the fine particles. In this connection, the organic conductive polymerizable material is a copolymer which is composed of a polythiophene derivative, a thiophene or a derivative thereof and pyrrole, aniline, fluorene, furan or a derivative thereof. Also disclosed is a method for producing such a composite material. This composite material is useful for display elements such as electronic paper.

    专利号:US-2429575-A
    优先权日:1944-09-16
    标 题:Synthesis of branched chain hydrocarbons
    发明人:APPLEBY WALTER G; LOVELL LAWRENCE L; LOVE MARK P L
    权利人:SHELL DEV

    专利号:US-8598166-B2
    优先权日:2008-03-21
    标 题:Polysubstituted derivatives of 6-heteroarylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof
    发明人:DE PERETTI DANIELLE; EVANNO YANNICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE
    权利人:DE PERETTI DANIELLE; EVANNO YANNICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; SANOFI SA
    摘要:Compounds of formula (I): n nwherein R 1 , R 2 , R 3 , R 4 , Het and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

    专利号:US-8338451-B2
    优先权日:2008-03-21
    标 题 :Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof
    发明人:DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO
    权利人:DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO; SANOFI SA
    摘要:Compounds of formula (I): n nwherein R, R 1 , R 2 , R 3 , R 4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Metal-Free Oxidative Coupling Reactions Via σ-Iodonium Intermediates: The Efficient Synthesis Of Bithiophenes Using Hypervalent Iodine Reagents
    作者:Koji Morimoto,Tomofumi Nakae,Nobutaka Yamaoka,Toshifumi Dohi,Yasuyuki Kita |发布日期:2011.11
    摘要:The Direct Oxidative Biaryl Coupling Reaction Is An Attractive Tool For Environmentally Benign Green Chemistry. A Novel Direct Method For The Synthesis Of Bithiophene Using A Hypervalent Iodine Reagent Has Been Developed. The Reaction Mechanism Has Also Been Investigated, Casting Light On The Reaction Intermediate And Revealing The Reactivity With Iodonium Salts.

    合成参考文献


    摘要:Sambiagio, C.; Maes, B. U. W., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 144.
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