CAS: 628-20-6; 4-Chlorobutyronitrile

相似化合物

627-00-9 2455-04-1 6139-84-0

上下游产品

CAS号2455-04-1 4-氯丁酰胺 | CAS号1119-46-6 5-氯戊酸 | CAS号109-70-6 1-溴-3-氯丙烷 | CAS号151-50-8 氰化钾 | CAS号109-74-0 正丁腈 | CAS号927-60-6 4-羟基丁酰胺 | CAS号77100-86-8 2,4-dichlorobut... | CAS号13435-20-6 氰化四乙基铵 | CAS号143-33-9 氰化钠 | CAS号96-48-0 γ-丁内酯 | CAS号40877-19-8 γ-氯-4-甲氧基苯丁酮 | CAS号3153-36-4 4-氯丁酸乙酯 | CAS号3153-37-5 4-氯丁酸甲酯 | CAS号35543-25-0 1-吡咯烷基丁腈 | CAS号5336-75-4 4-(二乙氨基)丁腈 | CAS号939-52-6 4-氯-1-羰基-1-苯基丁烷 | CAS号1859-29-6 4-[2-cyanoethyl... | CAS号22217-78-3 5-(4-氯苯基)-3,4-二... | CAS号21994-40-1 Butanenitrile, ... | CAS号2046-18-6 4-苯基丁腈

4-氯丁酰胺置于聚合甲醛,甲酸,乙腈体系中,化学反应 12.0H,以87%的收率获得产物4-氯丁腈
参考文献:通过醛催化的水转移将伯酰胺转化为腈.
标题:通过醛催化的水转移将伯酰胺转化为腈.
摘要:
DOI:10.1021/jo961128V

专利信息

专利号:US-2023312617-A1
优先权日:2020-07-25
标题 :Process for synthesis of organosilicon compounds from halosilanes
发明人：DOLAI SUKANTA; BHAT SHREEDHAR; TARAFDAR GOURAV
权利人:MOMENTIVE PERFORMANCE MAT INC
摘要:A process for synthesis of an organosilicon compound is provided herein. Also, novel organosilicon compounds prepared by the present process is provided herein. The process comprises the reaction of a halosilane with an organofunctional alkyl halide in the presence of a metal catalyst, a promoter, and an optional co-catalyst. The process provides an efficient synthetic route to produce organosilicon compounds. The process also allows synthesis of organosilicon compounds with a plurality of different functional groups.

专利号:US-5434152-A
优先权日:1993-11-08
标题:Asymmetric synthesis of (S)-(-)-6-chloro-4- cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone
发明人：HUFFMAN MARK A; YASUDA NOBUYOSHI; DECAMP ANN E; GRABOWSKI EDWARD J J
权利人:MERCK & CO INC
摘要:An asymmetric synthesis of (S)-(-)-6-chloro-4-cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone comprises the chiral addition of 2-pyridylacetylide to N 1 -protected 6-chloro-4-cyclopropyl-2-quinazolinone followed by removal of the protecting group.

专利号:US-9284343-B2
优先权日:2011-04-04
标 题:2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides
发明人：BEAUCAGE SERGE L; CIESLAK JACEK
权利人:BEAUCAGE SERGE L; CIESLAK JACEK; US HEALTH
摘要:Disclosed are O-protected compounds of the formula (I): n nwherein B is an optionally protected nucleobase, and R 1 -R 3 are as described herein, wherein at least one of R 1 -R 3 is —CH 2 —O—Nâ•?CHR. The compounds are useful as intermediates in oligonucleotide synthesis. Also disclosed is a method of preparing the compounds from nucleosides via a process comprising conversion of a hydroxyl group to a methylthiomethoxy group, and a method of preparing oligonucleotides such as RNA starting from the compounds. The —CH 2 —O—Nâ•?CHR group is stable during oligonucleotide synthesis and can be easily removed after synthesis via, for example, treatment with a base.

专利号:WO-2009140467-A1
优先权日:2008-05-15
标 题:Oxobenzindolizinoquinolines and uses thereof
发明人：CUSHMAN MARK S; CINELLI MARIS A; MORRELL ANDREW E; POMMIER YVES G
权利人:PURDUE RESEARCH FOUNDATION; CUSHMAN MARK S; US GOV HEALTH & HUMAN SERV; CINELLI MARIS A; MORRELL ANDREW E; POMMIER YVES G
摘要:The synthesis of aromathecins, substituted 12 H -5,l la-diazadibenzo[ b,h ]fluoren- 11 -ones is described. Use of these cytotoxic compounds and pharmaceutical compositions containing them for the treatment of cancer is described. Two novel processes for the synthesis of this system and a series of 14-substituted aromathecins as novel cytotoxic, topoisomerase I poisons are described.

专利号:US-8067460-B2
优先权日:2004-10-04
标 题 :5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel
发明人：WULFF HEIKE; SANKARANARAYANAN ANANTHAKRISHNAN; HAENSEL WOLFRAM; SCHMITZ ALEXANDER; SCHMIDT-LASSEN KRISTINA
权利人:WULFF HEIKE; SANKARANARAYANAN ANANTHAKRISHNAN; HAENSEL WOLFRAM; SCHMITZ ALEXANDER; SCHMIDT-LASSEN KRISTINA; UNIV CALIFONIA
摘要:Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).

专利号:WO-2012010644-A1
优先权日:2010-07-23
标 题:Process for the synthesis of isothiocyanates and derivatives thereof and uses of same