CAS: 594-60-5; 2,3-Dimethylbutan-2-Ol

该化合物是第三级酒精,其特点是其分支结构,包括两个附于丁醇链第二个碳的甲基组,其分子式为C6H14O,具有氢氧(OH)功能组,具有酒精特性.该化合物一般是一种无色液体,具有温和的气味,由于存在氢氧基,在水中可溶解,尽管其溶解性可能限于较简单的酒精. 2,3-二甲基-2-丁醇与其他酒精相比具有中等挥发性,其沸点相对较低,因此在各种应用中有用,包括作为一种溶剂和有机合成,其化学再活性包括典型的酒精反应,如形成脱水作用和氧化产生氯酮或藻类.安全考虑包括易燃性和对吸入或皮肤接触的潜在健康影响,需要适当的处理和储存措施.

结构式图片

相似化合物

3054-92-0 1517-67-5 76-09-5

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

trimethyloxirane diethyl ether methylmagnesium bromide 3-methyl-butan-2-one 3,5-dinitro-benzoic acid-(1,1,2-trimethyl-propyl ester) 2,3-Dimethyl-1-butene 2,3-dimethyl-2-butylamine 2,3-dimethyl-2,3-butane diol

合成工艺路线路线简述

    📜2,3-二甲基-1-丁烯置于三氟乙酸,三氟乙酸酐体系中,化学反应生成 2,3-二甲基-2-丁醇
    参考文献:Enthalpies Of Hydration Of Alkenes. 4. Formation Of Acyclic Tert-Alcohols
    标题:Enthalpies Of Hydration Of Alkenes. 4. Formation Of Acyclic Tert-Alcohols
    摘要:The Enthalpies Of Hydration Of A Series Of Acyclic Alkenes That Lead To Tert-Alcohols Were Determined. Several Pairs Of Alkenes That Give The Same Alcohol Were Studied And Gave The Differences In Enthalpy Of Formation Of The Alkenes. A Consistent Difference In Delta-H(F) Of 1.84 Kcal/mol Was Found Between Di-And Trisubstituted Alkenes. It Was Related To The Difference In Delta-H(F) For Pairs Of Exocyclic And Endocyclic Alkenes. The Enthalpies Of Formation Of The Alcohols Were Obtained And Were Related To Data For Primary And Secondary Alcohols.
    DOI:10.1021/jo00017A022

    海关参考信息

    专利信息


    专利号:WO-2024105700-A1
    优先权日:2022-11-18
    标 题:A method for the synthesis of anthranilic amide compounds and intermediates thereof
    发明人:MALVIYA NITIN; MAL SANJIB; KLAUSENER ALEXANDER G M
    权利人:PI INDUSTRIES LTD
    摘要:The present invention discloses a method for the synthesis of a compound of formula (V) or a salt thereof, wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The method further comprises the synthesis of an anthranilic diamide compound of formula (Z).

    专利号:US-2023339844-A1
    优先权日:2020-09-17
    标题:A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
    发明人:MAHAPATRA TRIDIB; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER G M; MAL SANJIB; SHARMA RAJU
    权利人:PI INDUSTRIES LTD; PI INDUSTRIES LTD
    摘要:The present invention disclosed a process for the synthesis of compound of formula (Z) or a salt thereof, n n n n n n n n n n wherein, R, R 1 , R 2 , R 3 and R 10 are as defined in the detailed description. The process further comprises the synthesis of an anthranilic diamide compound of formula (I).

    专利号:US-2023339906-A1
    优先权日:2020-09-26
    标 题 :A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
    发明人:SYTHANA SURESH KUMAR; NAGLE PRAMOD; KUMAR VIJAY KUMAR; KANAWADE SHRIKANT BHAUSAHEB; CHANDRE TUKARAM NIVRUTTI; THUBE VINAYAK KISAN; PATIL PRADEEP PRAKASH; SHUKLA SHALINI; SHENDE KANTILAL BALU; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER G M
    权利人:PI INDUSTRIES LTD; PI INDUSTRIES LTD
    摘要:The present invention discloses a process for the synthesis of compound of formula (VII) or a salt thereof,wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The process further comprises the synthesis of an anthranilic diamide compound of formula (I).

    专利号:US-10570114-B2
    优先权日:2016-05-19
    标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
    发明人:FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
    权利人:DOW AGROSCIENCES LLC
    摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.

    专利号:US-2013184465-A1
    优先权日:2010-09-30
    标 题:Process for the synthesis of thio-triazolo-group containing compounds
    发明人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
    权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
    摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

    专利号:US-9267213-B1
    优先权日:2005-03-25
    标题:Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
    发明人:MAURER KARL; COOPER JOHN J
    权利人:CUSTOMARRAY INC
    摘要:There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Gulseher Sarah Sirin, Et Al. Aging Mechanism Of Soman Inhibited Acetylcholinesterase. J Phys Chem B. 2012 Oct 11;116(40):12199-207.

    合成参考文献


    摘要:Herter, S.; Turner, N. J., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 107.
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