CAS: 56613-81-1; (S)-2-Amino-1-Phenylethanol

上下游产品

CAS号5468-37-1 2-氨基苯乙酮盐酸盐 | CAS号51096-49-2 S-(-)-2-苄基氨基-1-苯基乙醇 | CAS号70111-05-6 (S)-(+)-2-氯-1-苯乙醇 | CAS号69-96-5 DL-β-苯基丝氨酸 | CAS号25779-13-9 (S)-1-苯基-1,2-乙二醇 | CAS号40435-14-1 (S)-(+)-1-苯基-1,... | CAS号174500-20-0 2,6-双[|4S|-4-苯基... | CAS号14769-73-4 左旋咪唑

2-(Benzoylamino)-1-Phenylethanol置于盐酸,4 A Molecular Sieve体系中,用 四氢呋喃,甲醇,正己烷 作为反应溶剂,化学反应 120.0H,反应生成 (S)-2-氨基-1-苯乙醇
参考文献:Baker's Yeast Reduction Ofα-(Acylamino)Acetophenones And Lipase Catalyzed Resolution Of 2-Acylamino-1-Arylethanols
标题:Baker's Yeast Reduction Ofα-(Acylamino)Acetophenones And Lipase Catalyzed Resolution Of 2-Acylamino-1-Arylethanols
摘要:使用发酵的面包酵母对α-酰氨基苯乙酮进行酶促还原,得到了光学活性的(R)-2-酰氨基-1-芳基乙醇.进一步地,使用醋酸乙烯酯作为酰基供体,通过脂肪酶催化的拆分反应,反应生成了(S)-1-乙酰氧基-2-酰氨基-1-芳基乙醇和(R)-2-酰氨基-1-芳基乙醇.
DOI:10.1246/bcsj.66.1216

专利信息

专利号:US-2018312463-A1
优先权日:2015-10-22
标题:Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products
发明人：YELM KENNETH EDWARD; WOS JOHN AUGUST; BUNKE GREGORY MARK; FREDERICK HEATH; HAUGHT JOHN CHRISTIAN; HOKE STEVEN HAMILTON; SREEKRISHNA KOTI TATACHAR; LIN YAKANG
权利人:PROCTER & GAMBLE
摘要:Synthesis methods to produce a series of carboxamides built off of an (S)-2-amino acid backbone or an (R)-2-amino acid backbone, depending upon the desired diastereomer of the end product.

专利号:US-2008287407-A1
优先权日:2003-12-10
标题 :Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use
发明人：GARVEY DAVID S; FANG XINQIN; KHANAPURE SUBHASH P; RANATUNGA RAMANI R; WEY SHIOW-JYI
权利人:NITROMED INC
摘要:The invention describes novel nitrosated and/or nitrosylated pyruvate compounds and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated pyruvate compound, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one pyruvate compound and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one pyruvate compound, that is optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating diseases resulting from oxidative stress, diabetes, reperfusion injury following ischemia, preservation of tissues, organs, organ parts and/or limbs.

专利号:US-6414180-B1
优先权日:1998-03-04
标 题:Synthesis of chiral β-amino acids
发明人：COLSON PIERRE-JEAN; AWASTHI ALOK K; NAGARAJAN SRINIVASAN R
权利人:SEARLE & CO
摘要:The invention herein is directed to a process for the preparation of chiral beta-amino acids and esters of the formulawherein X and Y are the same or different halo groups, R2 is H or lower alkyl and isomers and pharmaceutically acceptable salts thereof.

专利号:US-2022048879-A1
优先权日:2020-08-13
标 题:Synthesis of small molecules inspired by Phomoxanthone A
发明人：ALI RAMEEZ; MATTSON ANITA
权利人:WORCESTER POLYTECH INST
摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

专利号:US-5932749-A
优先权日:1996-03-22
标 题:Asymmetric synthesis of R-α-propyl-piperonyl amine and its analogs
发明人：LI HUI-YIN; ANZALONE LUIGI; WALTERMIRE ROBERT EUGENE
权利人:DU PONT PHARM CO
摘要:Processes for the preparation of R- alpha -propyl-piperonyl amine and its analogs, such compounds being useful intermediates in the preparation of elastase inhibitors, and intermediates useful for making R- alpha -propyl-piperonyl amine are described.

专利号:US-5840961-A
优先权日:1996-07-12
标 题:Asymmetric synthesis of chiral beta-amiNo acids
发明人：BEHLING JAMES RICHARD; BOYS MARK LAURENCE; CAIN-JANICKI KIMBERLY JO; COLSON PIERRE-JEAN; DOUBLEDAY WENDEL WILLIAM; DURAN JOSEPH EDWARD; FARID PAYMAN N; KNABLE CARL MATTHEW; MUELLNER FRANK WALTER; NUGENT SEAN THOMAS; TOPGI RAVINDRA S
权利人:SEARLE & CO
摘要:The invention herein is directed to a process for the preparation of ethyl 3S-amino-4-pentynoate which involves treating 3-(trimethylsilyl)-2-propynal with L-phenylglycinol in toluene to produce αS- 3-(trimethylsilyl)-2-propynylidene amino!benzenethanol; reacting αS- 3-(trimethylsilyl)-2-propynylidene!amino!benzenethanol with BrZnCH 2 CO 2 t-Bu in THF/NMP to produce 1,1-dimethylethyl 3S- (2-hydroxy-1S-phenylethyl)amino!-5-(trimethylsilyl)-4-pentynoate; reacting the 1,1-dimethylethyl 3S- (2-hydroxy-1S-phenylethyl)amino!-5-(trimethylsilyl)-4-pentynoate with sodium periodate to form 1,1-dimethylethyl 3S- (phenylmethylene)amino!-5-(trimethylsilyl)-4-pentynoate; hydrolyzing 1,1-dimethylethyl 3S- (phenylmethylene)amino!-5-(trimethylsilyl)-4-pentynoate to produce 1,1-dimethylethyl 3S-amino-5-(trimethylsilyl)-4-pentynoate; transesterifying 1,1-dimethyl 3S-amino-5-(trimethylsilyl)-4-pentynoate and desilylating to produce ethyl 3S-amino-4-pentynoate.