CAS: 55314-30-2; 2,4-Dimethylpyridine-3-Carboxylic Acid

相似化合物

37669-78-6 194151-96-7 168072-32-0

上下游产品

CAS号37669-78-6 乙基2,4-二甲基吡啶-3-羧化物 | CAS号52199-37-8 2,4-二甲基-1,4-二氢吡... | CAS号1073-21-8 3-氨基-2,4-二甲基吡啶 | CAS号372156-99-5 2,4-二甲基吡啶-3-羧酸N-氧化物 | CAS号82776-24-7 3-Pyridinecarbo...

📜乙基2,4-二甲基吡啶-3-羧化物置于sodium Hydroxide,水,盐酸体系中,用 乙醇,甲醇,水 作为反应溶剂,化学反应 24.0H,以99%的收率获得产物2,4-二甲基吡啶-3-羧酸
参考文献:Derivatives Of 4-(N-Azacycloalkyl) Anilides As Potassium Channel Modulators
标题:Derivatives Of 4-(N-Azacycloalkyl) Anilides As Potassium Channel Modulators
摘要:这项发明提供了钾通道调节剂,其化合物为公式i,其中w和z中至少有一个是n;其中基团为下面的a或b之一: A 其中ar是一个1,2-融合的六元环芳香基团,带有以下定义的取代基r1和r2,并含有零个或一个环氮原子;其他取代基在此处定义. 该发明还提供了一种组合物,包括一种药学上可接受的载体和以下至少一种:I) 公式i的化合物的药学有效量,以及ii) 其药学上可接受的盐,酯或前药. 该发明还提供了一种预防或治疗受钾通道活动影响的疾病或紊乱的方法,包括向有需要的患者施用公式i的化合物或其盐,酯或前药的治疗有效量.

专利信息

专利号:US-6992189-B2
优先权日:2002-03-29
标 题 :Synthesis of piperidine and piperazine compounds as CCR5 antagonists
发明人：LEONG WILLIAM; CHEN MINZHANG; D SA BOSCO A; ZHU MAN; XIAO TONG; SHI XIONGWEI; TANG SUHAN; GALA DINESH; GOODMAN ANDREW J; NIELSEN CHRISTOPHER M; LEE GARY M; GAMBOA JUAN A; JONES ANDREW D
权利人:SCHERING CORP
摘要:In its several embodiments, this invention discloses novel processes to prepare the compounds of formula II and formula IV:

专利号:US-2004024217-A1
优先权日:2002-03-29
标题 :Synthesis of piperidine and piperazine compounds as CCR5 antagonists

专利号:JP-2005521743-A
优先权日:2002-03-29
标 题 :Synthesis of piperidine and piperazine compounds as CCR5 antagonists

专利号:US-2005187248-A1
优先权日:2002-03-29
标题 :Synthesis of piperidine and piperazine compounds as CCR5 antagonists

专利号:CA-2480482-A1
优先权日:2002-03-29
标 题:Synthesis of piperidine and piperazine compounds as ccr5 antagonists

专利号:ZA-200406546-B
优先权日:2002-03-29
标 题:Synthesis of piperidine and piperazine compounds as CCR5 antagonists.