CAS: 548-82-3; (2R,3R)-3,5,7-Trihydroxy-2-Phenylchroman-4-One

上下游产品

(S)-2-Methyl-butyric acid (2R,3R)-5,7-dihydroxy-4-oxo-2-phenyl-chroman-3-yl ester 2,4,6-trihydroxyacetophenone 3,5,7-trihydroxy-2-phenylchroman-4-one 2,4,6-tri-MOM phloracetophenone

📜(S)-2-Methyl-Butyric Acid (2R,3R)-5,7-Dihydroxy-4-Oxo-2-Phenyl-Chroman-3-Yl Ester置于氢氧化钾体系中,用 甲醇 作为反应溶剂,以0.2 Mg的收率获得产物短叶松素
参考文献:Constituents Of Chinese Propolis And Their Antiproliferative Activities
标题:Constituents Of Chinese Propolis And Their Antiproliferative Activities
摘要:Two New Flavonoids,3-O-[(S)-2-Methylbutyroyl]Pinobanksin (1) And 6-Cinnamylehrysin (2),Were Isolated From The Etoac-Soluble Fraction Of The Meoh Extract Of Chinese Propolis,Along With 12 Known Compounds (3-14). The Structures Of The Isolated Compounds Were Elucidated On The Basis Of Spectroscopic And Chemical Analyses. The Isolated Compounds Were Tested For Their Antiproliferative Activity Toward Five Different Cancer Cell Lines. Benzyl Caffeate (13) And Phenethyl Caffeate (14) Showed Potent Antiproliferative Activity Toward Tested Cell Lines With A Selective Activity Toward Colon 26-L5 Carcinoma Cell Line (Ec50 Values: 13,1.01; 14,0.30 Mum).
DOI:10.1021/np010486C

专利信息

专利号:WO-2023149795-A1
优先权日:2022-02-07
标题:Method for producing an entomological compound with a keratolytic effect
发明人：CIUHRII CESLAV
权利人:CIUHRII CESLAV
摘要:The invention relates to the field of biotechnology and can be used in cosmetology and pharmaceutics for treating keratoses of various origins and in cosmetic exfoliating procedures. A method for producing an active entomological compound with a high degree of keratolytic activity consists in raising insects until the seventh larval instar (21-23 days after hatching) on a first nutrient medium having a specific composition, and subsequently transferring them to a second nutrient medium which differs from the first in that it contains a larger quantity of wax and a smaller quantity of honey and further contains zinc acetate as a protein synthesis stimulator. The insects are grown for 180 hours, after which the larvae are harvested, frozen at -18°С, washed and ground at a temperature of 20°С, lyophilized, re-ground at an extremely low temperature of -55°С, homogenized, packaged and stored in a freezer compartment at -18°С. The invention makes it possible to obtain a larger quantity of larval biomass and to increase the keratolytic activity of the target product.