CAS: 5392-12-1; 2-Methoxy-1-Naphthaldehyde

相似化合物

947-62-6 40696-22-8 13343-92-5

上下游产品

hydrogen cyanide 2-Methoxynaphthalene 2,2,2-trichloro-1-(2-methoxy-[1]naphthyl)-ethanol (2-methoxy-[1]naphthyl)-glyoxylic acid 2-methoxy-1-methylnaphthalene (2-methoxy-[1]naphthyl)-pyruvic acid 4-(2-methoxy-5,6-benzobenzylidene)-2-phenyl-5-oxazolone 2-methoxy-1-naphthoic acid

2-甲氧基-1-萘甲醇置于pyridinium Chlorochromate体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 2-甲氧基-1-萘醛
参考文献:Evaluation Of Synthetic Naphthalene Derivatives As Novel Chemical Chaperones That Mimic 4-Phenylbutyric Acid
标题:Evaluation Of Synthetic Naphthalene Derivatives As Novel Chemical Chaperones That Mimic 4-Phenylbutyric Acid
摘要:The Chemical Chaperone 4-Phenylbutyric Acid (4-Pba) Has Potential As An Agent For The Treatment Of Neurodegenerative Diseases. However,The Requirement Of High Concentrations Warrants Chemical Optimization For Clinical Use. In This Study,Novel Naphthalene Derivatives With A Greater Chemical Chaperone Activity Than 4-Pba Were Synthesized With Analogy To The Benzene Ring. All Novel Compounds Showed Chemical Chaperone Activity,And 2 And 5 Possessed High Activity. In Subsequent Experiments,The Protective Effects Of The Compounds Were Examined In Parkinson'S Disease Model Cells,And Low Toxicity Of 9 And 11 Was Related To Amphiphilic Substitution With Naphthalene. (C) 2015 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2014.12.080

专利信息

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-5175302-A
优先权日:1987-07-13
标 题 :Nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:US-4837327-A
优先权日:1987-07-13
标 题 :Process for nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to alkehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:US-4999429-A
优先权日:1989-01-09
标 题 :Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:WO-9710221-A1
优先权日:1995-09-15
标 题:Synthesis of quinazolinone libraries
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TORREY PINES INST
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-7056348-B2
优先权日:2001-04-19
标题:5-aryl-1,3,3-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibers
发明人：SAUTER GUIDO; BRAUN HANS-JUERGEN; REICHLIN NADIA
权利人:WELLA AG
摘要:A method for the synthesis of 5-aryl-1,3,3,-trimethyl-2-methylene-indoline derivatives of Formula (I) or its salts of Formula (Ia) wherein 1 mole of a 5-aryl-2,3,3-trimethyl-3H-indole derivative of Formula (VII) is reacted for 1 to 44 hours at a temperature of 20° to 180° C. in an apolar, aprotic or polar, protic or polar aprotic solvent with 1 to 50 moles of a compound of Formula R1-A; new compounds of Formulas (I)/(Ia) and (V), obtainable by this method as well as an agent containing at least one compound of Formula (I)/(Ia) and a carbonyl/imine compound for dyeing keratinic fibers and a method for temporarily dyeing keratin fibers, for which the keratin fiber is dyed with the aforementioned agent and the dyeing, so obtained, is removed again at any later time by a sulfite preparation.